Onc Now: Episode 3: Redefining Breast Cancer

This week, Jonathan Sackier is joined by Prof. Carlos Caldas, a world-leading expert in breast cancer research and clinician scientist at the University of Cambridge. Together, they explore how genomic-based classifications of breast cancer are transforming treatment strategies and improving patient outcomes. 

Timestamps:

(00:00) – Introduction 

(02:00) – Carlos’s favourite cuisine  

(03:32) – Carlos’s journey into oncology  

(08:30) – The redefinition of breast cancer  

(14:30) – How this taxonomy influences clinical care  

(20:15) - Patient-derived xenografts for breast cancer  

(28:00) - Circulating plasma cell-free tumour DNA as a marker of tumour burden  

(33:00) – Patient derived tumour cells for drug screening  

(35:00) – Vitamin B5 and environmental factors in oncology  

(38:44) – Current developments in breast cancer aetiology, diagnosis or treatment   

(44:00) – The three wishes for the future of healthcare  

(45:00) – Outro