It's in the Air: Silica exposure and the risk of autoimmunity, Part 4

What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out!

·       Intro 0:12

·       In the previous episodes 0:28

·       The Ajax incident of 1979 1:15

·       Silica and its association with autoimmune disease 4:11

·       The history of silica and the health risks 5:21

·       Rheumatoid scleroderma, etc. 8:14

·       Cardiff pneumoconiosis medical panel 9:49

·       Databases 12:51

·       Silica exposure and the development of serologies 15:02

·       What would happen if you injected silica into the veins? 16:51

·       Anca vasculitis 18:33

·       Thanks for listening 23:23

Disclosures: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum.

References:

Blanc PD, et al. Am J Med. 2015;doi:10.1016/j.amjmed.2015.05.001.

Boudigaard SH, et al. Int J Epidemiol. 2021;doi:10.1093/ije/dyaa287.

Conrad K, et al. Lupus. 1996;doi:10.1177/096120339600500112.

Hoy RF, et al. Allergy. 2020;doi:10.111/all.14202.

Klockars M, et al. Br Med J (Clin Res Ed). 1987;doi:10.1136/bmj.294.6578.997.

Park CG, et al. Environ Health Perspect. 1999;doi:10.1289/ehp.99107s5793.

Pollard KM. Front Immunol. 2016;doi:10.3389/fimmu.2016.00097.