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In this episode, Nick and Nathan go over the endotoxemia hypothesis of atherogenesis and the major knowns and unknowns in heart disease. This episode is also available in video form on the Root Causing Health YouTube.

In this episode, Nick goes over the key characteristics of atherogenesis and the observations we have to explain. He also discusses the characterization of the disease and the transient behavior of coronary calcium scores (and therefore the difficulty of using them in the short term). Here’s a transcript of the episode.

Nick gives an overview of the state of atherosclerosis research and explains why we haven’t identified what’s going on.

Today we’re discussing Sean’s research on optimizing health. Sean uses MRIs to view people’s internal fat or Visceral Adipose Tissue (VAT). We discuss Sean’s personal journey through health, discovery of MRIs as a viable marker, and experience helping people obtain optimal health.

Join us as we deep dive into the nuance of plaque progression with Nadir Ali. We get Nadir’s take on the endotoxemia hypothesis of plaque formation and atherogenesis, discuss the lipoprotein’s role in the body and immune system, and identify some key areas of focus for future research in holistic management of cardiovascular disease.

Gabor discusses his research into immune health with Root Causing Health.