Medizin - Open Access LMU - Teil 08/22

Ludwig-Maximilians-Universität München
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Medizin - Open Access LMU - Teil 08/22

Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 8. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)

  1. 01/01/1991

    10 years of experience with autogenous microsurgical lymphvessel-transplantation

    The authors report their experience with the autogenous microsurgical lymphvessel transplantation for the treatment of upper (n = 60, 55 females and 5 males) and lower (n = 35, 10 females and 25 males, primary lyphredemas = 11, secondary lymphredemas = 24) limb edemas. Regarding the volume measurements before and after lymphvessel - transplantation in 58 patients there was a reduction of volume differences between healthy and affected arms of more than the half in 76 % of the patients after a mean follow-up period of 2 1/2 years. In 28 patients with unilateral redemas of the lower extremities the volume reduction after a mean follow-up period of I 1/2 year compared to the healthy legs was more than 50 % in 20 patients. As complications in the early period 2 postoperative erysipelas were seen. One patient developed a Iymph cyst in the groin and one patient had a postthrombotic lower leg rederna. The authors conclude that lymphvessel transplantations therefore seem to be a method to enhance significantly the lymphatic transport if by conservation me ans alone no long term success is seen.

  2. 01/01/1991

    61-jähriger Patient mit massiven, rezidivierenden gastrointestinalen Blutungen und Aortenstenose

    Medizin - Open Access LMU - Teil 08/22

  3. 01/01/1991

    A Nonparametric Method for the Derivation of α/β Ratios from the Effect of Fractionated Irradiations

    Multifractionation isoeffect data are commonly analysed under the assumption that cell survival determines the observed tissue or tumour response, and that it follows a linear-quadratic dose dependence. The analysis is employed to derive the α/β ratios of the linear-quadratic dose dependence, and different methods have been developed for this purpose. A common method uses the so-called Fe plot. A more complex but also more rigorous method has been introduced by Lam et al. (1979). Their method, which is based on numerical optimization procedures, is generalized and somewhat simplified in the present study. Tumour-regrowth data are used to explain the nonparametric procedure which provides α/β ratios without the need to postulate analytical expressions for the relationship between cell survival and regrowth delay.

  4. 01/01/1991

    A chloride channel in rat and human axons

    Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at negative membrane potentials and 65 pS at positive potentials (symmetrical 150 mM CsCl). They were measurably for cations (PNa/PCs/PCl=0.1/0.2/1). Channel currents were independent of cytoplasmatic calcium concentration. Inactivation was not observed and gating was weakly voltage dependent. Cl− channels in human axons showed similar gating behavior but had a lower conductance.

  5. 01/01/1991

    A compilation of geometric reduction factors for standard geometries

    Medizin - Open Access LMU - Teil 08/22

  6. 01/01/1991

    A porous implant system (Porecon) for facial reconstruction and augmentation

    Medizin - Open Access LMU - Teil 08/22

  7. 01/01/1991

    Altered bile composition during gallstone formation

    Medizin - Open Access LMU - Teil 08/22

  8. 01/01/1991

    Altered density of glomerular binding sites for atrial natriuretic factor in bile duct-ligated rats with ascites

    The renal response to atrial natriuretic factor is blunted in cirrhosis with ascites. This might be due to alterations of renal receptors for atrial natriuretic factor. Therefore density and affinity of glomerular atrial natriuretic factor binding sites of bile duct-ligated rats with ascites (n = 10) and of sham-operated controls (n = 10) were determined. Glomerular atrial natriuretic factor binding sites were identified to be of the B-(biologically active) and C-(clearance) receptor type. Discrimination and quantitative determination of B and C receptors for atrial natriuretic factor were achieved by displacement experiments with atrial natriuretic factor(99-126) or des(18-22)atrial natriuretic factor(4-23), an analogue binding to C receptors only. Density of total glomerular atrial natriuretic factor binding sites was significantly increased in bile duct-ligated rats (3,518 ± 864 vs. 1,648 ± 358 fmol/mg protein; p 0.05). This was due to a significant increase of C-receptor density (3,460 ± 866 vs. 1,486 ± 363 fmol/mg protein; p 0.05), whereas density of B receptors was not significantly different in bile duct-ligated rats (58 ± 11 vs. 162 ± 63 fmol/mg protein). Affinity of atrial natriuretic factor to its glomerular binding sites did not differ significantly between both groups. These data suggest that an altered glomerular atrial natriuretic factor receptor density could be involved in the renal resistance to atrial natriuretic factor in cirrhosis with ascites.

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Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 8. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)

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