AJT Highlights American Journal of Transplantation

Host Roz is joined by AJT Executive Guest Editor Nadim Mahmud, MD, MPH (University of Pennsylvania) and AJT Editorial Fellow Tina Marinelli, MBBS, MPH&TM,  FRACP (Royal Prince Alfred Hospital).

 
[03:10] Semidirected Living Donors in Israel: Sociodemographic Profile, Religiosity, and Social Tolerance
 
[11:54] TCRseq Reveals Selected Donor-reactive CD8+ T cell Clones Resist Anti-Thymocyte Globulin Depletion after Kidney Transplantation
 
[18:47] Natural killer cell functional genetics and donor-specific antibody-triggered microvascular inflammation
 
[26:36] Surgical site infections after kidney transplantation are independently associated with graft loss
 
[38:26] Introduction to Virtual Special Issue, Insights into ACLF: From Pathogenesis to Interventions
 
[39:21] Immunopathogenesis of acute on chronic liver failure
 
[43:43] Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!

Host Roz is joined by AJT Editor-in-Chief Emeritus Allan Kirk, MD, PhD, (Duke University) and AJT Editorial Fellow Laura Binari, MD (Vanderbilt University).
[2:34] Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates
[14:09] A2/A2B to B deceased donor kidney transplantation in the Kidney Allocation System era
[24:01] Xenotransplantation Papers
[25:07] Xenotransplantation experiments in brain-dead human subjects–A critical appraisal
[28:11] The decedent model: A new paradigm for de-risking high stakes clinical trials like xenotransplantation
[32:45] Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

Host Roz is joined by AJT Editorial Board Member Alexandre Loupy, MD, PhD (Necker Hospital) and AJT Editorial Fellow Thiago J Borges, PhD (Massachusetts General Hospital).
[2:39] Transplanting old organs promotes senescence in young recipients
[11:33] The Banff 2022 Kidney Meeting Report: Reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics
[15:45] The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts
(Editorial) [18:12] The Banff process—Reloaded: A joint initiative from the Banff Foundation for Allograft Pathology and the American Journal of Transplantation
[20:25] Antiobesity pharmacotherapy to facilitate living kidney donation
[27:04] Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients

Host Roz is joined by AJT Editorial Board Member John Greenland, MD, PhD (University of California, San Francisco) and AJT Editorial Fellow David Cron, MD, MS (Massachusetts General Hospital).
[2:53] Pure laparoscopic donor hepatectomy: Experience of 556 cases at Seoul National University Hospital
[11:26] Smoking exposure-induced bronchus-associated lymphoid tissue in donor lungs does not prevent tolerance induction after transplantation & Aging exacerbates murine lung ischemia-reperfusion injury by excessive inflammation and impaired tissue repair response
[20:28] Augmenting the Unites States transplant registry with external mortality data: A moving target ripe for further improvement
(Editorial) How hard are the hard outcomes reported in national transplant registries?
[32:25] Maintaining the permanence principle of death during normothermic regional perfusion in controlled donation after the circulatory determination of death: Results of a prospective clinical study

The podcast discusses the impact and implications the kidney allocation system (KAS 250) has had over kidney allocation in the United States, focusing on the effect on operational challenges, cold ischemic times, delayed graft function, and organ discard rates.
Guest speakers include Joel Adler (Dell Medical School, University of Texas in Austin) and John Friedewald (Northwestern Memorial Hospital).

Host Roz is joined by AJT Editorial Board Member Michael Mengel, MD (University of Alberta) and AJT Editorial Fellow Kazem Fallahzadeh, MD (Emory University).
[2:43] Recurrent atypical antiglomerular basement membrane nephritis in the kidney transplant
[14:26] Pretransplantation coronavirus disease 2019 vaccination requirements: A matched case-control study of factors associated with waitlist inactivation
(Editorial) Coronavirus disease 2019 vaccine mandates and the Owl of Minerva
[21:45] Incomplete tissue product tracing during an investigation of a tissue-derived tuberculosis outbreak
[29:48] Risk for graft loss in pediatric and young adult kidney transplant recipients due to recurrent IgA nephropathy
[37:07] De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy