Two Brad For You

Bradley van Paridon
Podcast: Two Brad For You

A science show that doesn't sound like all the others. Join science journalist Brad van Paridon as he explores all manner of weird science topics with friends from all walks of life and through discussions with scientists and science journalists.

  1. 22 AGO

    Episode 98 - How does science go mainstream and how to respond when it does

    The great science broadcaster and author Jay Ingram joins me once again to talk about science that goes mainstream. Why does do some topics jump out of dedicated science news channels and how should critics respond? Is there any good way to present the process behind science and why is that crucial for critiques of misleading stories. These are some of the topics we explore and Jay provides some positive examples of efforts to communicate the changing nature and long term vision of scientific research. We pose many questions about how best to tell science stories and not all were answered but just like research, communication is an ever evolving thing as well. Let me know what you think about science media and where you'd like to see change. This is the only link you need to subscribe to Two Brad For You. Please do rate and review it really helps us out. If you'd like to support the show with currency click here. We are grateful for that too. Finally, you can check out the website here. Many thanks to Freak Motif for the music and Sebastian Abboud for the logo. Dementia prevention, intervention, and care: 2024 report of the Lancet standing CommissionYes, Social Media Really Is a Cause of the Epidemic of Teenage Mental Illness - Jonathan HaidtThe great rewiring: is social media really behind an epidemic of teenage mental illness?Unsettled science on social media - ScienceDefy Dementia Podcast

    1 h 5 min
  2. 15 LUG

    Episode 97 - An unexpected hurdle for MDMA assisted therapy. What now?

    In June an independent advisory committee recommended the FDA not approve MDMA assisted therapy for PTSD. This came as a surprise to many working in and following the field of psychedelic assisted therapy. It also raised questions as to where the field is at and what challenges still exist. To provide some context and perspective on this decision and some of the specific criticism raised during the hearing Henrik Jungaberle, a psychedelic and public health researcher in Berlin joined the show. This is the only link you need to subscirbe and never miss an episode of Two Brad For You. Please do rate and review it really helps us out. If you'd like to support the show with currency click here. We are grateful for that too. Finally, you can check out the website here. Many thanks to Freak Motif for the music and Sebastian Abboud for the logo. The MIND FoundationMethodological challenges in psychedelic drug trials: Efficacy and safety of psilocybin in treatment-resistant major depression (EPIsoDE) – Rationale and study design - ScienceDirectTreatment with psychedelics is psychotherapy: beyond reductionism - The Lancet PsychiatryMeasuring psychotherapeutic processes in the context of psychedelic experiences: Validation of the General Change Mechanisms Questionnaire (GCMQ) - Journal of Psychopharmacologyent...Was the FDA Panel Right to Recommend Against MDMA Approval? - MedPage TodayPsychiatric Drug Developers Make Recommendations Following Lykos Adcomm - BioSpaceAn emotional public hearing on MDMA: ‘Today you will vote on whether my friends live or die’

    58 min
  3. 22 FEB

    Episode 94 - What do ants teach us about living in groups and with disease?

    Ants and other eusocial insects have taken group living to the extreme and while we may not think of these animals as representative of human societies studying the fundementals of the evolution of and consequences of social living using ants makes a lot of sense. My guest Yuko Ulrich is a behavioral ecologist and group leader at the Max Planck Institute for Chemical Ecology in Jena, Germany. She joined me to discuss how she uses a unique ant species, commonly known as the clonal raider ant, to ask basic questions regarding evolution and behavior. She explains why the clonal raider ants are such a useful model system and discusses the results from two studies that look at the evolution of group living itself and how an individuals behavior within a group affects their risk for disease. This conversation really highlights the importance of experimental biology for asking and answering questions that may seem obvious but that must answered before we can discover exactly why group living is so succesful or understand how groups evolved to defend against disease. It was also a nice reminder that working together in the face of an outbreak offers unique defenses solitary individuals don't have. Finally, we touch on what happens when the parasite takes things to the extreme and manipulates host behavior. That's right, zombie parasites. Links to both of the studies discussed can be found below. Fitness benefits and emergent division of labour at the onset of group living | NatureBehavioural individuality determines infection risk in clonal ant colonies | Nature Communications This is the only link you need to subscirbe and never miss an episode of Two Brad For You. Please do rate and review it really helps us out. If you'd like to support the show with currency click here. We are grateful for that too. Finally, you can check out the website here. Many thanks to Freak Motif for the music and Sebastian Abboud for the logo. Listen to Two Brad For You Support this Podcast

    1 h 10 min
  4. 22/12/2023

    Episode 92 - Gene Editing Cures Cholesterol and Sickle Cell Diseases But At What Cost?

    Two major breakthroughs in gene editing recently occurred and show how our ability to edit the human genome is rapidly increasing. This episode we dive into how these technologies work and how they were able to treat two diseases. One a rather mundane sounding cholesterol problem and the other an exteremely painful and potentially deadly condition known as sickle cell disease. Both stories invovle a combination of new technologies, mRNA techniques and gene editing either using or inspired by CRISPER. These stories highlight how all of these technologies are combining to open new possibilities, that gene editing may become just a regular treatment as we age, and the less talked about downsides or hidden trade-offs that come with these treatments. Sources Base editing, a new form of gene therapy, sharply lowers bad cholesterol in a clincal trial - Science A Closer Look at the Approval of CRISPR/Cas9 Gene Therapy for Sickle Cell Disease - MedPage Today New gene therapies confront many sickle cell patients with an impossible choice: a cure or fertility - STAT WE WANT TO HEAR FROM YOU! Head to www.twobradforyou.wordpress.com to subscribe to, donate to and follow the show on social media. You can also leave a comment, send an email or voice message. We read/listen to them all and will put them on air. This is your show too so get involved and don't let Brad have all the fun.

    1 h 5 min

Descrizione

A science show that doesn't sound like all the others. Join science journalist Brad van Paridon as he explores all manner of weird science topics with friends from all walks of life and through discussions with scientists and science journalists.

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