22 episodi
Yale Center for Clinical Investigation Yale University
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- Salute e benessere
Faculty associated with the Yale Center for Clinical Investigation talk about their efforts to put knowledge to work for patients. They tell stories of research that helps obese children achieve a healthy body weight, addresses the root causes of cardiovascular disease in African Americans and offers the parents of autistic children proven strategies to help their children – in other words, research with real-life benefits.
The Yale Center for Clinical Investigation was launched in 2006 to support and promote clinical research, which works directly with patients, and translational research, which applies basic laboratory science to clinical problems. It was one of the first 12 centers awarded a Clinical and Translational Science Award by the National Institutes of Health. Its mission is to help scientists and doctors bring research discoveries from the laboratory to the clinic to patients in New Haven and around the world.
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The Dangers of "Everyday" Discrimination
Dr. Lewis has found that African-Americans who report a high rate of slights and mistreatments also show metabolic indicators that they are at risk for cardiovascular disease. Her future work will look at coping skills to help people avoid the dangerous health effects of discrimination, while also probing ways to reduce that discrimination.
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Translators Wanted
Dr. Robert Sherwin draws upon his career doing landmark research in diabetes to help new investigators pursue science that improves health care. Reflecting on his role as primary investigator of Yale’s NIH Clinical and Translational Science Award, he sees a need to educate “translators,” researchers who can connect basic scientists and clinicians.
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Vision for Clinical and Translational Research at Yale
William Tamborlane’s groundbreaking research changed the way diabetes is managed, but he says that research of that kind is becoming increasingly difficult to do. As YCCI Deputy Director for Clinical Research and Director of the Office of Research Services, Dr. Tamborlane works to remove barriers for the next generation of clinical researchers.
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Removing Barriers to Innovation
Kathleen Uscinski of Yale’s Office of Human Research Protection is streamlining clinical research by working at Yale and with institutions around the country to find ways to ensure safety without creating unnecessary bureaucracy.
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Heal Thyself
Erik Shapiro’s lab is working to manipulate dormant stem cells to migrate to sites of injury or disease so that the body can effect its own repairs. He terms this out-of-the-box approach “high risk/high reward” science.
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A Measured Approach
Associate Dean for Scientific Affairs Sara Rockwell talks about the pragmatic approach that Yale takes in evaluating the effectiveness of the Yale Center for Clinical Investigation.