OPENPediatrics

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Unveiling MIS-C's Immune Response: Molecular Mimicry by A. Randolph and A. Bodansky | OPENPediatrics

In this World Shared Practice Forum Podcast, Drs. Adrienne Randolph and Aaron Bodansky explore the groundbreaking research findings that uncover the pathophysiological mechanism behind multisystem inflammatory syndrome in children (MIS-C). These findings shed light on the characteristic immune response of patients who develop MIS-C, and provide insight into the development of post-infectious auto-immune disease phenotypes. LEARNING OBJECTIVES - Describe the pathophysiology of MIS-C, including the clinical features and molecular immune response - Describe the immune dysregulation that results in MIS-C, including the role of autoantibodies and T-cell responses - Identify the potential connections between SARS-CoV-2 infection and the development of autoimmune responses - Recognize the implications of the study findings for other related conditions such as long COVID and sepsis AUTHORS Adrienne Randolph, MD, MSc Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anaesthesia and Pediatrics Harvard Medical School Aaron Bodansky, MD Assistant Professor Pediatric Critical Care University of California, San Francisco School of Medicine DATES Initial publication: September 24, 2024. ARTICLES REFERENCED Bodansky A, Mettelman RC, Sabatino JJ Jr, et al. Molecular mimicry in multisystem inflammatory syndrome in children. Nature. 2024;632(8025):622-629. doi:10.1038/s41586-024-07722-4. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Randolph AG, Bodansky A, Burns JP. Unveiling MIS-C's Immune Response: Molecular Mimicry. 09/2024. OPENPediatrics. https://soundcloud.com/openpediatrics/unveiling-mis-cs-immune-response-molecular-mimicry-by-a-randolph-and-a-bodansky-openpediatrics

24 min
9 SEPT

Drop the Jargon: Improving Written Communication to Families After Multidisciplinary Care

In this Complex Care Journal Club podcast episode, Ms. de Pins and Dr. Lin discuss a quality improvement initiative to standardize post-visit written communication in a multidisciplinary clinic. They describe stakeholder involvement in defining project goals, effective interventions to reduce the use of medical jargon in after-visit summaries, and next steps from this work. SPEAKERS Agathe de Pins, BSc, MSc Medical Student Icahn School of Medicine at Mount Sinai Elaine Lin, MD Co-Director, Cerebral Palsy and Spasticity Center Pediatrician, Complex Care Service, Boston Children's Hospital HOST Kristina Malik, MD Assistant Professor of Pediatrics, University of Colorado School of Medicine Medical Director, KidStreet Pediatrician, Special Care Clinic, Children's Hospital Colorado DATE Initial publication: September 9, 2024. JOURNAL ARTICLE de Pins AM, Adu-Amankwah D, Shadman KA, Hess SM, Elaiho CR, Butler LR, Ranade SC, Shah BJ, Fields R, Lin EP. A Quality Improvement Project to Improve After-visit Summary Patient Instructions in a Pediatric Multidisciplinary Neuromuscular Program. Pediatr Qual Saf. 2024 Jul 10;9(4):e743. doi: 10.1097/pq9.0000000000000743. PMID: 38993270; PMCID: PMC11236396. OTHER REFERENCES Gidengil C, Parast L, Burkhart Q, Brown J, Elliott MN, Lion KC, McGlynn EA, Schneider EC, Mangione-Smith R. Development and Implementation of the Family Experiences With Coordination of Care Survey Quality Measures. Acad Pediatr. 2017 Nov-Dec;17(8):863-870. doi: 10.1016/j.acap.2017.03.012. Epub 2017 Mar 31. PMID: 28373108. Hess SM, Adu-Amankwah D, Elaiho CR, Butler LR, Ranade SC, Shah BJ, Shadman K, Fields R, Lin EP. Qualitative feedback from caregivers in a multidisciplinary pediatric neuromuscular clinic. J Pediatr Rehabil Med. 2024;17(2):237-246. doi: 10.3233/PRM-230011. PMID: 38427510; PMCID: PMC11306999. TRANSCRIPT https://op-docebo-images.s3.amazonaws.com/Transcripts/Drop+the+Jargon_Lin+and+de+Pins_090924.pdf Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: forms.gle/Bdxb86Sw5qq1uFhW6 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION de Pins AM, Lin EP, Malik K. Drop the Jargon: Improving Written Communication to Families After Multidisciplinary Care. 9/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/drop-the-jargon-improving-written-communication-to-families-after-multidisciplinary-care

19 min
4 SEPT

Anesthesia for Non-Cardiac Surgeries: Unrepaired TOF | OPENPediatrics

This podcast discusses anesthetic considerations for patients with unrepaired tetralogy of Fallot who are undergoing non-cardiac surgeries. LEARNING OBJECTIVES Upon listening to this podcast, learners will be able to: - Explain preoperative considerations - Provide an anesthetic management plan - Describe specific non-cardiac surgical procedures and the considerations that need to be addressed when performing them - Anticipate the postoperative considerations AUTHORS Annette Schure, MD Senior Associate in Cardiac Anesthesia Boston Children's Hospital Assistant Professor of Anesthesia Harvard Medical School Christian Refakis, MD Clinical Fellow Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital Robert Soohey Medical Student Tufts University School Of Medicine DATES Initial publication: September 4, 2024. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Refakis C, Marcley S, Soohey R, Marques B, Wolbrink TA, Schure AY. Anesthesia for Non-Cardiac Surgeries: Unrepaired TOF. 09/2024. OPENPediatrics. Podcast: https://soundcloud.com/openpediatrics/anesthesia-for-non-cardiac-surgeries-unrepaired-tof-openpediatrics.

26 min
26 AUG

Collaborative Care Models to Optimize Care of HSCT Patients by T. Wolbrink et al. | OPENPediatrics

In this World Shared Practice Forum Podcast, experts from three large pediatric hospitals discuss their collaborative care models designed to optimize care for patients undergoing hematopoietic stem cell transplant. This global panel reviews the history, structure, and current state of these models, and offers insight into how clinicians can develop and improve their own collaborative care models. LEARNING OBJECTIVES - Identify the importance of collaborative care models for hematopoietic stem cell transplant patients - Discuss the status of current care models in three pediatric stem cell transplant programs - Apply insights on how clinicians develop collaborative care models and steps that can be taken to make ongoing improvements AUTHORS Asya Agulnik, MD, MPH Associate Member, St. Jude Faculty Director, Global Critical Care Program Director, Euro Regional Program St. Jude Children’s Research Hospital Indira Jayakumar, MD Lead Pediatric Intensivist Apollo Specialty Cancer Hospitals Co Convenor- IAP Transplant Critical Care, Chairman- Pediatric wing, ECMO Society of India Chennai, Tamil Nadu, India Leslie Lehmann, MD Attending Physician, Pediatric Stem Cell Transplant Center Boston Children's Hospital/Dana Farber Cancer Institute Associate Professor of Pediatrics Harvard Medical School Revathi Raj, MBBS, DCH, PLAB, MRCP, FRCPath Senior Consultant Department of Pediatric Hematology and Oncology and Blood and Marrow Transplantation Apollo Hospitals Chennai, Tamil Nadu, India Adrienne Randolph, MD, MSc Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anaesthesia and Pediatrics Harvard Medical School Aimee C. Talleur, MD Assistant Member, Department of Bone Marrow Transplantation and Cellular Therapy Fellowship Director, BMTCT Fellowship Program St. Jude Children's Research Hospital DATES Initial publication: August 26, 2024. ARTICLES REFERENCED • Zinter MS, McArthur J, Duncan C, et al. Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network’s Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. Pediatr Crit Care Med. 2022;23(3):205-213. doi:10.1097/PCC.0000000000002865 (13:04) • St. Jude Global Critical Care program, https://global.stjude.org/en-us/programs/transversal-programs/critical-care.html, Email: globalcriticalcare@stjude.org (25:49) Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Agulnik A, Jayakumar I, Lehmann L, Raj R, Randolph AG, Talleur AC, Wolbrink TA. Collaborative Care Models to Optimize Care of Hematopoietic Stem Cell Transplant Patients. 08/2024. OPENPediatrics. Podcast https://soundcloud.com/openpediatrics/collaborative-care-models-to-optimize-care-of-hsct-patients-by-t-wolbrink-et-al-openpediatrics.

42 min
5 AUG

Choice and Voice: Family Perspectives on Decision-making for Children with Medical Complexity

In this Complex Care Journal Club podcast episode, Dr. Kate Nelson discusses a qualitative study exploring decision-making skills developed by family caregivers of children with medical complexity. She describes the impact of contextual factors and relationships within care teams on decision-making, family partnership in research, and the next steps from this work. SPEAKER Kate Nelson, MD, PhD Staff Pediatrician, Paediatric Advanced Care Team The Hospital for Sick Children Scientist SickKids Research Institute Assistant Professor University of Toronto HOST Kathleen Huth, MD, MMSc Pediatrician, Complex Care Service, Division of General Pediatrics Boston Children's Hospital Assistant Professor of Pediatrics Harvard Medical School DATE Initial publication date: August 5, 2024. Journal Club Article Finlay M, Chakravarti V, Buchanan F, Dewan T, Adams S, Mahant S, Nicholas D, Widger K, McGuire KM, Nelson KE. Learning to Trust Yourself: Decision-Making Skills Among Parents of Children With Medical Complexity. J Pain Symptom Manage. 2024 May 28:S0885-3924(24)00792-9. doi: 10.1016/j.jpainsymman.2024.05.023. Epub ahead of print. PMID: 38810951. TRANSCRIPT https://op-docebo-images.s3.amazonaws.com/Transcripts/Choice+and+Voice+Family+Perspectives+on+Decision-making+for+Children+_nelson_080524.pdf Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Nelson K, Huth K. Choice and Voice: Family Perspectives on Decision-making for Children with Medical Complexity. 8/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/choice-and-voice-family-perspectives-on-decision-making-for-children-with-medical-complexity

26 min
10 JUL

Tonsillectomy | OPENPediatrics

This podcast discusses the preoperative, operative, and postoperative considerations for patients undergoing tonsillectomy, including anatomy and pathophysiology, preoperative evaluation, anesthetic management, operative approach, and postoperative care. LEARNING OBJECTIVES Upon listening to this podcast, learners will be able to: • Explain the anatomy and pathophysiology • Describe key considerations for the preoperative anesthetic evaluation and intraoperative anesthetic management plan • Review common operative approaches • Discuss postoperative considerations AUTHORS Haley Moulton, BA MS4 Geisel School of Medicine at Dartmouth Eelam Adil, MD, MBA, FAAP Associate Department of Otolaryngology and Communication Enhancement Boston Children's Hospital Assistant Professor of Otolaryngology Harvard Medical School Ashish Ankola, MD Assistant Professor of Pediatrics Texas Children's Hospital Sonya Mathews Pre-Medical Student Jue Wang, MD Associate in Perioperative Anesthesia Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital DATES Initial publication date: July 10, 2024 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Moulton H, Adil E, Ankola A, Mathews S, Wang JT, Marcley S, McFee AM, Wolbrink TA. Tonsillectomy. 07/2024. OPENPediatrics. Podcast. https://soundcloud.com/openpediatrics/tonsillectomy-openpediatrics

21 min
1 JUL

Upholding Human Dignity for Children with Medical Complexity and their Families

In this Complex Care Journal Club podcast episode, Ms. Bethlyn Vergo Houlihan and Ms. Meg Comeau discuss a qualitative study of the perspectives of families of children with medical complexity on what is needed to promote their quality of life and well-being. They describe the family-led approach to designing and conducting the study, the importance of upholding human dignity as a major theme, and next steps to translate their findings into systems change. SPEAKERS Bethlyn Vergo Houlihan, MSW, MPH Project Director, Principal Investigator Center for Innovation in Social Work & Health Boston University School of Social Work Meg Comeau, MHA Senior Project Director/Principal Investigator Center for Innovation in Social Work and Health Boston University School of Social Work HOST Kristina Malik, MD Assistant Professor of Pediatrics, University of Colorado School of Medicine Medical Director, KidStreet Pediatrician, Special Care Clinic, Children's Hospital Colorado DATE Initial publication date: July 1, 2024. JOURNAL CLUB ARTICLES Houlihan BV, Coleman C, Kuo DZ, Plant B, Comeau M. What Families of Children With Medical Complexity Say They Need: Humanism in Care Delivery Change. Pediatrics. 2024 Jan 1;153(Suppl 1):e2023063424F. doi: 10.1542/peds.2023-063424F. PMID: 38165241. Randolph G, Coleman C, Allshouse C, Plant B, Kuo DZ. Measuring What Matters to Children With Medical Complexity and Their Families. Pediatrics. 2024 Jan 1;153(Suppl 1):e2023063424C. doi: 10.1542/peds.2023-063424C. PMID: 38165239. TRANSCRIPT chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://op-docebo-images.s3.amazonaws.com/Transcripts/Upholding+Human+Dignity+for+Children+with+Medical+Complexity+and+their+Families_070124.pdf Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Houlihan BV, Comeau M, Malik K. Upholding Human Dignity for Children with Medical Complexity and their Families. 7/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/upholding-human-dignity-for-children-with-medical-complexity-and-their-families

33 min
25 JUN

Inflammatory Bowel Disease by J. Ouahed, L. Collen | OPENPediatrics

This podcast provides an overview of the presentation of inflammatory bowel disease (IBD) and compares it to Crohn's disease and ulcerative colitis phenotypes. LEARNING OBJECTIVES By the end of this podcast, the learner will be able to: • Recognize the clinical presentation of inflammatory bowel disease and compare Crohn's disease and ulcerative colitis phenotypes. • Plan the diagnostic evaluation of patients with suspected IBD. • Define treatment goals and list available treatment options. AUTHORS Jodie Ouahed, MD, MMSc Director, VEOIBD Clinic Attending Physician, Inflammatory Bowel Disease Center, Boston Children's Hospital Assistant Professor, Harvard Medical School Lauren Collen, MD Attending Physician, Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital Instructor of Pediatrics, Harvard Medical School DATES Initial publication: June 25, 2024 Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Collen LV*, Ouahed J*, Brodie K, Wills K, Combs A, Snapper SB. Inflammatory Bowel Disease. 6/2024. OPENPediatrics. Podcast: https://soundcloud.com/openpediatrics/inflammatory-bowel-disease-by-j-ouahed-l-collen-openpediatrics. *These authors contributed equally to this work

10 min

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Podcast by OPENPediatrics

Creator

OPENPediatrics
Years Active

2015 - 2024
Episodes

500
Rating

Clean
Show Website

OPENPediatrics

OPENPediatrics

Unveiling MIS-C's Immune Response: Molecular Mimicry by A. Randolph and A. Bodansky | OPENPediatrics

Drop the Jargon: Improving Written Communication to Families After Multidisciplinary Care

Anesthesia for Non-Cardiac Surgeries: Unrepaired TOF | OPENPediatrics

Collaborative Care Models to Optimize Care of HSCT Patients by T. Wolbrink et al. | OPENPediatrics

Choice and Voice: Family Perspectives on Decision-making for Children with Medical Complexity

Tonsillectomy | OPENPediatrics

Upholding Human Dignity for Children with Medical Complexity and their Families

Inflammatory Bowel Disease by J. Ouahed, L. Collen | OPENPediatrics

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OPENPediatrics

Episodes

Unveiling MIS-C's Immune Response: Molecular Mimicry by A. Randolph and A. Bodansky | OPENPediatrics

Drop the Jargon: Improving Written Communication to Families After Multidisciplinary Care

Anesthesia for Non-Cardiac Surgeries: Unrepaired TOF | OPENPediatrics

Collaborative Care Models to Optimize Care of HSCT Patients by T. Wolbrink et al. | OPENPediatrics

Choice and Voice: Family Perspectives on Decision-making for Children with Medical Complexity

Tonsillectomy | OPENPediatrics

Upholding Human Dignity for Children with Medical Complexity and their Families

Inflammatory Bowel Disease by J. Ouahed, L. Collen | OPENPediatrics

About

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