Digital-Pathology-Today

Magpie Communications
Digital-Pathology-Today

Digital Pathology Today, the only podcast for professionals interested in the field of digital pathology and artificial intelligence in a clinical setting. This interview-style podcast features industry leaders, key academics, and top pathologists discussing the past, present and future of digital pathology. Hosted by pathologist, Dr. Joseph Anderson, each weekly episode discusses topics from artificial intelligence to regulation and much more. “We hope to bring news and information to anyone interested in the field of digital pathology,” said Digital Pathology Today host, Dr. Joseph Anderson. “With so many advances and innovations taking place, we know that Digital Pathology Today will be a valuable source of information for our listeners.”

  1. 18 NOV

    October 2024 Digital Pathology Roundup

    Imogen Fitt from Signify Research joins us for the October Digital Pathology Roundup, which highlights significant developments in digital pathology and related fields, focusing on funding, telepathology, generative AI, and enterprise imaging. Funding: Mindpeak GmbH secured $15.3 million in Series A funding led by ZEISS Ventures and other notable investors, aiding product development and geographic expansion. Aignostics raised €31.4 million in Series B funding, backed by Athos Partners and Mayo Clinic Ventures, to enhance its platform for translational research and companion diagnostics, following a partnership with Bayer. StratifAI obtained €1.5 million in pre-seed funding from Neulogy Ventures and others to support digital biomarker development for breast cancer and biopharma services. Telepathology Services: Inify Laboratories announced its expansion into the UK market, focusing on prostate cancer diagnostics, backed by SEK 150 million funding to develop AI for gastrointestinal diagnostics. Originally part of ContextVision AB, Inify pivoted to telepathology using AI. In the US, NorDx adopted PreciPoint's Advanced Digital Pathology Solutions for frozen section diagnostics, emphasizing AI’s role in improving diagnostic turnaround times, a trend supported by investments from major players like Quest Diagnostics. Generative AI: Proscia introduced "Concentriq Embeddings" and a Developer Toolkit to assist AI development for life sciences. These tools use foundation models like DINOv2 and ConvNext to generate data embeddings from slide images, enabling customized AI workflows and integration. Enterprise Imaging: Gestalt partnered with Optum to integrate its PathFlow solution into Optum’s Enterprise Imaging Suite. This collaboration, involving Change Healthcare (acquired by Optum), represents a strategic move to advance digital pathology within enterprise healthcare platforms.These advancements underline the growing role of AI and digital solutions in pathology, fostering innovation and collaboration across the industry

    14 min
  2. 4 OCT

    September 2024 Digital Pathology Roundup

    September's round-up highlights significant advancements in AI integration, structured reporting, real-world data (RWD), hematology, and funding in the digital pathology space. Aiforia Technologies partnered with Assistance Publique–Hôpitaux de Paris (AP-HP) to introduce AI-based prostate solutions into clinical use, backed by regional funding from Île-de-France. This initiative aims to study AI's impact in clinical care, with the potential for broader AI implementation across France, as AP-HP plans to expand AI usage across all its pathology departments. Proscia and Smart Reporting GmbH also joined forces, integrating SmartReports, a structured reporting tool, into Proscia’s Information Management System (IMS). Structured reporting enables the generation of standardized medical reports that facilitate large-scale data comparison and analysis. This tool is crucial for precision medicine and better understanding diseases in RWD studies. Smart Reporting has a strong presence in the radiology field and was highlighted in a comprehensive Imaging IT round-up. Proscia further introduced an RWD solution on its Concentriq® platform, integrating over 10 million pathology images with clinical and genomic data. This tool offers life sciences organizations access to de-identified patient data for drug development and marks a pivotal step toward making IMS platforms essential links between research and clinical applications. In hematology, Beckman Coulter Diagnostics and Scopio Labs expanded their partnership, adding the Full-Field Bone Marrow Aspirate (FF-BMA) application to their existing automated hematology solutions. This marks a successful continuation of their collaboration, which began in 2023.

    13 min
  3. 13 SEPT

    August 2024 Digital Pathology Roundup

    Imogen Fitt from Signify Research joins us to recap the news and events of August. Paige recently announced several key changes, starting with the appointment of Razik Yousfi as the new CEO. Paige is transitioning its diagnostic AI applications to a standalone solution compatible with other digital pathology platforms. Additionally, the company partnered with Indica Labs, integrating AI models into Indica’s workflow software and focusing on joint commercial efforts in pharma services, preclinical, and translational applications. This shift away from the IMS follows challenges such as market demand for interoperability and slow clinical growth. Paige also announced that its cancer research models, Virchow and PRISM, will be open-source, while advanced versions remain commercially licensed, aiming to boost algorithm usage through its collaboration with Microsoft. Roche expands its digital pathology open environment by integrating over 20 AI algorithms from eight collaborators to enhance cancer diagnostics and precision medicine. On the funding front, PreciseDx secured $20 million in a Series B round to commercialize PreciseBreast™ risk assessment. Labcorp and Quest Diagnostics' involvement signals growing interest from major labs in digital pathology (DP). Similarly, SigTuple raised $4 million to expand geographically, focusing on its AI-powered diagnostics product AI100, which received FDA clearance and is expanding into various global markets. In partnerships, Tribun Health teamed up with Ibex Medical Analytics to integrate Ibex’s AI solutions into its CaloPix platform, offering services in the EU, US, and Canada. Tribun Health’s future AI strategy emphasizes workflow efficiency, strategic collaborations, and interoperability, positioning the company for broader platform integration. Lastly, Ibex Medical Analytics and PathAI both received IVDR certifications, marking growth milestones for their prostate, breast, and gastric AI solutions. PathAI also announced new developments regarding its IMS platform. These moves highlight a growing momentum in AI-driven diagnostics and partnerships in the healthcare sector.

    12 min
  4. 1 AUG

    July 2024 Digital Pathology Roundup

    The July Digital Pathology Round-up with Imogen Fitt of Signify Research is here. Nucleai and Proscia Partnership: Nucleai and Proscia have partnered to integrate Nucleai's AI Predictive Biomarker algorithms into Proscia's Concentriq platform. This collaboration aligns with the rising interest in digital companion diagnostics (CDx) in clinical trials and diagnostics. The demand for imaging biomarkers is driving rapid investments, especially from pharmaceutical companies, which will influence the digitization of clinical labs. Proscia also updated its digital pathology software, adding DICOM image support and a multi-AI overlay feature, enabling the use of multiple AI tools in the pathology workflow. UK Pathology and Genomics Collaboration: The National Pathology Imaging Co-operative (NPIC) partnered with CellPath to install two Whole Slide Imaging (WSI) scanners, connecting them to NPIC's national digital pathology system. These scanners will create a digital archive for the 100,000 Genomes Project, a precision medicine initiative. This integration aims to enhance genomics research and develop prognostic algorithms for patient stratification. Asia-Pacific Developments: 3DHISTECH announced Epredia China as its new distributor. Indica Labs announced new reseller agreements in the Asia-Pacific region, covering the Philippines, Thailand, Vietnam, and Malaysia. Indica Labs plans to pursue IVD registrations, indicating growth opportunities in the APAC region. Generative AI in Digital Pathology: Scientists from Weill Cornell Medicine and Dana-Farber Cancer Institute developed generative AI tools based on ChatGPT for digital pathology. These tools provide accurate responses to digital pathology queries and help pathologists with PathML, a library for DP image analysis. While impactful in academic circles, concerns about accountability and regulation limit their clinical application. Philips received 510(k) clearance for its IntelliSite Pathology Solution 5.1, signaling potential competitive dynamics in the US digital pathology market. Funding Announcements: Scopio Labs raised $42 million in a Series D round led by Fortissimo Capital, aiming to expand globally with a focus on the US market. Clarapath secured $36 million in a Series B-1 round to commercialize its automated microtomy system, SectionStar.

    12 min
  5. 20 JUN

    SEASON 3, EPISODE 13 - Andre Esteva, PhD - Personalizing Treatment Decisions through Artificial Intelligence

    Today we are discussing how treatment decisions can be personalized through artificial intelligence and digital pathology. Our guest is Andre Esteva of Artera. Atera’s first product is in prostate cancer. We discuss how AI can improve upon the current state of the practice which largely relies on making decisions based on clinical nomograms. We discuss the concepts prediction and prognosis and how both are incorporated into treatment decisions; what goes into developing and validating AI based algorithms in digital pathology and the importance of validating these algorithms in the appropriate studies specifically randomized clinical trials. There is one huge advantage of AI based digital pathology tools over genomics and molecular tools. Image based tools can be performed instantaneously rather than waiting days to weeks. Andre Esteva is a researcher and entrepreneur in medical artificial intelligence. He currently serves as CEO of Artera and was previously Head of Medical AI at Salesforce Research. He has worked at Google Research, Sandia National Labs, GE Healthcare, and has founded four companies. His research efforts have largely focused on medical AI diagnostics and precision medicine. His publications have made the covers of Nature and Nature Medicine, and have been featured in Cell, The Lancet, NeurIPS, and similar venues. These works have been widely covered by the WSJ, Fortune, BBC, The Economist, and hundreds of other news outlets.

    27 min
  6. 13 JUN

    The Journey to Pathology 3.0, EPISODE 1 - Branko Perunovic, MD, FRCPath

    What is pathology 3.0? We are at an inflection point. The demand on pathologists in laboratory medicine is greater than ever. Demographics and healthcare needs of the population are shifting. New technologies such as digital pathology and molecular diagnostics are now a reality. The rules of the game are changing. There are times in any industry where massive change is inevitable and there is great opportunity to grow. And for this, we need a new mindset. Pathology 1.0 was transactional. Clinicians would send in the specimen we would send the results. Passive and fragmented. Not responsive. Pathology 2.0 involved consolidation, taking advantage of economies of scale and scope. But still transactional and fragmented. Pathology 3.0 is connected, intelligent and evolving. Pathologists can add unique value and build on previous waves of consolidation. It transcends the boundaries of disciplines and organizational silos. It integrates new technologies and is interactive. Branko Perunovic is Chief Medical Officer at Black Country Pathology Service, where he leads the pathology consolidation and the delivery of high-quality and innovative pathology services. His journey has taken him through various aspects of healthcare, including transforming pathology services, consolidating labs, fostering collaborative team dynamics, and pioneering the integration of digital pathology and digital innovation in laboratory medicine. His ultimate goal is simple: to improve patient care, making the pathology service the provider, employer, and investment of choice. Together with a dedicated team, we can achieve this vision and create a healthcare landscape that truly puts patients first.

    10 min

About

Digital Pathology Today, the only podcast for professionals interested in the field of digital pathology and artificial intelligence in a clinical setting. This interview-style podcast features industry leaders, key academics, and top pathologists discussing the past, present and future of digital pathology. Hosted by pathologist, Dr. Joseph Anderson, each weekly episode discusses topics from artificial intelligence to regulation and much more. “We hope to bring news and information to anyone interested in the field of digital pathology,” said Digital Pathology Today host, Dr. Joseph Anderson. “With so many advances and innovations taking place, we know that Digital Pathology Today will be a valuable source of information for our listeners.”

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