Research To Practice | Oncology Videos

Research To Practice | Oncology Videos

Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

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    Lymphoma | What Clinicians Want to Know About the Current and Future Role of EZH1/2 Inhibitors in the Care of Patients with Lymphoma

    Featuring an interview with Dr Gilles Salles, including the following topics: Epigenetic modifications and the role of EZH2 in the pathobiology of follicular lymphoma (FL) (0:00) Natural history of FL and current treatment landscape in the first-line setting (5:20) Testing approaches for the detection of EZH2 mutations (14:37) Mechanism of action of the EZH inhibitors tazemetostat and valemetostat (18:31) Tazemetostat monotherapy as treatment for relapsed/refractory FL (20:58) Ongoing evaluation of novel treatment approaches with tazemetostat for FL and other lymphomas (25:31) Approved indications for tazemetostat for wild-type FL and FL with EZH2 mutations; sequencing of tazemetostat with bispecific antibodies and CAR T-cell therapy (34:07) Available clinical data with the novel dual EZH1/EZH2 inhibitor valemetostat (42:37) Personal experience with CAR T-cell therapy and perspectives on possible underlying reasons for the development of T-cell lymphoma in patients receiving this treatment (44:35) Management of FL in patients who experience relapse within 24 months of receiving treatment (POD24) (48:25) Myths or misperceptions associated with tazemetostat and other therapies approved in the relapsed FL setting (52:15) Perspectives on the future treatment landscape of FL (54:29) CME information and select publications

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Featuring the video recorded proceedings of events held in conjunction with important scientific symposia, live webcasts and closed meetings featuring the perspectives of renowned clinical investigators, these videos provide an overview of important advances in the management of a number of solid tumors and hematologic cancers.

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