The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)

Sam Charrington
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The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence) Podcast

Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

  1. 4 DAYS AGO

    Supercharging Developer Productivity with ChatGPT and Claude with Simon Willison

    Today, we're joined by Simon Willison, independent researcher and creator of Datasette to discuss the many ways software developers and engineers can take advantage of large language models (LLMs) to boost their productivity. We dig into Simon’s own workflows and how he uses popular models like ChatGPT and Anthropic’s Claude to write and test hundreds of lines of code while out walking his dog. We review Simon’s favorite prompting and debugging techniques, his strategies for sidestepping the limitations of contemporary models, how he uses Claude’s Artifacts feature for rapid prototyping, his thoughts on the use and impact of vision models, the role he sees for open source models and local LLMs, and much more. The complete show notes for this episode can be found at https://twimlai.com/go/701.

    1h 14m

  2. 3 SEPT

    Automated Design of Agentic Systems with Shengran Hu

    Today, we're joined by Shengran Hu, a PhD student at the University of British Columbia, to discuss Automated Design of Agentic Systems (ADAS), an approach focused on automatically creating agentic system designs. We explore the spectrum of agentic behaviors, the motivation for learning all aspects of agentic system design, the key components of the ADAS approach, and how it uses LLMs to design novel agent architectures in code. We also cover the iterative process of ADAS, its potential to shed light on the behavior of foundation models, the higher-level meta-behaviors that emerge in agentic systems, and how ADAS uncovers novel design patterns through emergent behaviors, particularly in complex tasks like the ARC challenge. Finally, we touch on the practical applications of ADAS and its potential use in system optimization for real-world tasks. The complete show notes for this episode can be found at https://twimlai.com/go/700.

    60 min

  3. 27 AUG

    The EU AI Act and Mitigating Bias in Automated Decisioning with Peter van der Putten

    Today, we're joined by Peter van der Putten, director of the AI Lab at Pega and assistant professor of AI at Leiden University. We discuss the newly adopted European AI Act and the challenges of applying academic fairness metrics in real-world AI applications. We dig into the key ethical principles behind the Act, its broad definition of AI, and how it categorizes various AI risks. We also discuss the practical challenges of implementing fairness and bias metrics in real-world scenarios, and the importance of a risk-based approach in regulating AI systems. Finally, we cover how the EU AI Act might influence global practices, similar to the GDPR's effect on data privacy, and explore strategies for closing bias gaps in real-world automated decision-making. The complete show notes for this episode can be found at https://twimlai.com/go/699.

    46 min

  4. 19 AUG

    The Building Blocks of Agentic Systems with Harrison Chase

    Today, we're joined by Harrison Chase, co-founder and CEO of LangChain to discuss LLM frameworks, agentic systems, RAG, evaluation, and more. We dig into the elements of a modern LLM framework, including the most productive developer experiences and appropriate levels of abstraction. We dive into agents and agentic systems as well, covering the “spectrum of agenticness,” cognitive architectures, and real-world applications. We explore key challenges in deploying agentic systems, and the importance of agentic architectures as a means of communication in system design and operation. Additionally, we review evolving use cases for RAG, and the role of observability, testing, and evaluation tools in moving LLM applications from prototype to production. Lastly, Harrison shares his hot takes on prompting, multi-modal models, and more! The complete show notes for this episode can be found at https://twimlai.com/go/698.

    59 min

  5. 12 AUG

    Simplifying On-Device AI for Developers with Siddhika Nevrekar

    Today, we're joined by Siddhika Nevrekar, AI Hub head at Qualcomm Technologies, to discuss on-device AI and how to make it easier for developers to take advantage of device capabilities. We unpack the motivations for AI engineers to move model inference from the cloud to local devices, and explore the challenges associated with on-device AI. We dig into the role of hardware solutions, from powerful system-on-chips (SoC) to neural processors, the importance of collaboration between community runtimes like ONNX and TFLite and chip manufacturers, the unique challenges of IoT and autonomous vehicles, and the key metrics developers should focus on to ensure optimal on-device performance. Finally, Siddhika introduces Qualcomm's AI Hub, a platform developed to simplify the process of testing and optimizing AI models across different devices. The complete show notes for this episode can be found at https://twimlai.com/go/697.

    47 min

  6. 5 AUG

    Genie: Generative Interactive Environments with Ashley Edwards

    Today, we're joined by Ashley Edwards, a member of technical staff at Runway, to discuss Genie: Generative Interactive Environments, a system for creating ‘playable’ video environments for training deep reinforcement learning (RL) agents at scale in a completely unsupervised manner. We explore the motivations behind Genie, the challenges of data acquisition for RL, and Genie’s capability to learn world models from videos without explicit action data, enabling seamless interaction and frame prediction. Ashley walks us through Genie’s core components—the latent action model, video tokenizer, and dynamics model—and explains how these elements collaborate to predict future frames in video sequences. We discuss the model architecture, training strategies, benchmarks used, as well as the application of spatiotemporal transformers and the MaskGIT techniques used for efficient token prediction and representation. Finally, we touched on Genie’s practical implications, its comparison to other video generation models like “Sora,” and potential future directions in video generation and diffusion models. The complete show notes for this episode can be found at https://twimlai.com/go/696.

    47 min

  7. 30 JUL

    Bridging the Sim2real Gap in Robotics with Marius Memmel

    Today, we're joined by Marius Memmel, a PhD student at the University of Washington, to discuss his research on sim-to-real transfer approaches for developing autonomous robotic agents in unstructured environments. Our conversation focuses on his recent ASID and URDFormer papers. We explore the complexities presented by real-world settings like a cluttered kitchen, data acquisition challenges for training robust models, the importance of simulation, and the challenge of bridging the sim2real gap in robotics. Marius introduces ASID, a framework designed to enable robots to autonomously generate and refine simulation models to improve sim-to-real transfer. We discuss the role of Fisher information as a metric for trajectory sensitivity to physical parameters and the importance of exploration and exploitation phases in robot learning. Additionally, we cover URDFormer, a transformer-based model that generates URDF documents for scene and object reconstruction to create realistic simulation environments. The complete show notes for this episode can be found at https://twimlai.com/go/695.

    57 min

  8. 23 JUL

    Building Real-World LLM Products with Fine-Tuning and More with Hamel Husain

    Today, we're joined by Hamel Husain, founder of Parlance Labs, to discuss the ins and outs of building real-world products using large language models (LLMs). We kick things off discussing novel applications of LLMs and how to think about modern AI user experiences. We then dig into the key challenge faced by LLM developers—how to iterate from a snazzy demo or proof-of-concept to a working LLM-based application. We discuss the pros, cons, and role of fine-tuning LLMs and dig into when to use this technique. We cover the fine-tuning process, common pitfalls in evaluation—such as relying too heavily on generic tools and missing the nuances of specific use cases, open-source LLM fine-tuning tools like Axolotl, the use of LoRA adapters, and more. Hamel also shares insights on model optimization and inference frameworks and how developers should approach these tools. Finally, we dig into how to use systematic evaluation techniques to guide the improvement of your LLM application, the importance of data generation and curation, and the parallels to traditional software engineering practices. The complete show notes for this episode can be found at https://twimlai.com/go/694.

    1h 20m
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Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.

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