Migration – Darwin College Lecture Series 2018

Cambridge University
《Migration – Darwin College Lecture Series 2018》Podcast

In the second term of every academic year since 1986 Darwin College has organised a series of eight public lectures. Each series has been built around a single theme, approached in a multi-disciplinary way, and with each lecture prepared for a general audience by a leading authority on his or her subject. The theme of the 2018 lecture series is "Migration".

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  1. 06/03/2018

    Migration in Science

    Progress in science depends on a rapid exchange of ideas and exposure to new approaches and viewpoints. Historically, this progress has been accelerated by the movement of people. Scientists have been among the most mobile of people, going where they perceive the action to be. This talk will explore examples from various periods in history on how mobility resulted in scientific development. It will also describe the reasons behind the moves in my own peripatetic life. Biography Venki Ramakrishnan received his bachelor’s degree in physics from Baroda University in India in 1971 and his Ph.D. in physics from Ohio University in 1976. He then studied biology for two years at the University of California, San Diego before beginning his postdoctoral work with Peter Moore at Yale University. After a long career in the US, he moved to England in 1999 to become a group leader at the MRC Laboratory of Molecular Biology in Cambridge. He is also the current president of the Royal Society. Ramakrishnan has a long-standing interest in ribosome structure and function. In 2000, his laboratory determined the atomic structure of the 30S ribosomal subunit and its complexes with ligands and antibiotics. This work has led to insights into how the ribosome “reads” the genetic code, as well as into various aspects of antibiotic function. Ramakrishnan’s lab subsequently determined high-resolution structures of functional complexes of the entire ribosome at various stages along the translational pathway, which has led to insights into its role in protein synthesis during decoding, peptidyl transfer, translocation and termination. More recently his laboratory has been applying cryoelectron microscopy to study eukaryotic and mitochondrial translation.

    1 小時 4 分鐘
  2. 19/02/2018

    Disease Migration

    Dr. Eva Harris: Dengue and Zika are mosquito-borne viral diseases that consitute major public health and medical problems worldwide. Dengue has been a scourge for decades and only continues to increase in magnitude, geographic distribution, and severity, whereas Zika recently took the world by surprise with a dramatic epidemic in the Americas that was linked to severe congenital defects, including microcephaly, when infection occurred during pregnancy. In this lecture, “Migration of dengue and Zika viruses: Across continents, around cities, and within the human host”, we will explore the concept of “migration” as applied to dengue and Zika on multiple levels. First, we will examine the emergence and spread of these viruses seen through both epidemiological and phylogenetic lenses, through studies of human populations and viral sequences. Next, we will focus on spatial studies of dengue and Zika transmission in our cohort study of children in Managua, Nicaragua, where we have observed differences in Zika virus transmission at a hyper local level, allowing identification of hot-spots and environmental risk factors. Finally, we will turn to “migration” of dengue and Zika viruses within the human body, via studies of intrahost diversity of these RNA viral sequences in different bodily compartments as well as visualization of Zika virus invasion of the human placenta. Through this unusual interpretation of the concept of migration, we hope to introduce multiple themes in research and public health of these important human infectious diseases.

    1 小時 7 分鐘

關於

In the second term of every academic year since 1986 Darwin College has organised a series of eight public lectures. Each series has been built around a single theme, approached in a multi-disciplinary way, and with each lecture prepared for a general audience by a leading authority on his or her subject. The theme of the 2018 lecture series is "Migration".

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