246. Isoxazolines

Isoxazolines are anti-parasitics that inhibit chloride channels in the nervous systems of invertebrates. This paralyzes and kills parasites by blocking the transmission of neuronal signals. 

Isoxazolines are more selective to fleas, ticks, and mites than to mammals, including humans, dogs and cats. It has been a game changer for our flea allergic pets and treating mange cases.

Learn some of the specific differences of these products on this week's episode of The Derm Vet podcast!

TIMESTAMPS
00:00 Intro
00:25 Before Isoxazolines 
02:28 What is Isoxazolines
04:34 Afoxolaner
06:18 Sarolaner
08:03 Lotilaner
09:10 Fluralaner
11:28 Summary
13:05 Outro