Matters Microbial

Mark O. Martin
Matters Microbial

Matters Microbial is a podcast about the wonders of microbiology, microbiologists, and microbial centrism with Dr. Mark Martin

  1. HACE 6 DÍAS

    Digesting the Science of Fermented Foods

    Matters Microbial #66: Digesting the Science of Fermented Foods November 20, 2024 Today, Dr. Ben Wolfe, Associate Professor of Biology at Tufts University, joins the #QualityQuorum to discuss how he and his collaborators study novel food fermentations, helping the public understand more about the gut microbiome, and outreach projects involving microbially-associated food. Host: Mark O. Martin Guest: Benjamin Wolfe Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview for beginning Micronauts on microbial fermentation. A more advanced overview of microbial fermentation. A book and website that I highly recommend by Sandor Katz on the subject, including many recipes and background information. The bacterially derived volatile chemical geosmin. An article describing the relationship between geosmin and springtails. An article about leaf cutter ants and how they farm fungi!  I hope to do an entire podcast on this topic soon. An article of Dr. Wolfe and colleague’s work showing a relationship between fungal antibiotics and cheese microbiome development.  Dr. Rob Dunn’s “Belly Button Microbiome” project, a community science effort. An overview of the community science effort to explore sourdough bread microbiology. An overview of cheese microbiology. A description of cheesemaking and cheese caves.  A cheesemaker with which Dr. Wolfe has worked. A link to a remarkable article by Dr. Wolfe’s research group that we discussed in this episode:  “Novel Fermentations Integrate Traditional Practic and Rational Design of Fermented-Food Microbiomes.” A video of a presentation by Dr. Wolfe on cheese microbiology. Dr. Wolfe’s faculty website at Tufts University. A website by Dr. Wolfe and coworkers promoting microbial literacy via understanding the positive relationship between food and microbes. The website of Dr. Wolfe’s research group. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

    1 h y 7 min
  2. 7 NOV

    Making Sense of the Microbiome

    Today, Dr. Patrick Schloss, Professor in the Department of Microbiology and Immunology in the School of Medicine at the University of Michigan, joins the #QualityQuorum to discuss how the human microbiome is studied, possible pitfalls in such data analysis, and what tools he and his coworkers have developed to lead toward repeatable, hypothesis-driven science. Host: Mark O. Martin Guest: Patrick Schloss Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of how the gut microbiome is analyzed. One of the articles discussed by Dr. Schloss exploring reproducibility in microbiome studies: “Identifying and Overcoming Threats to Reproducibility, Replicability, Robustness, and Generalizability in Microbiome Research.” Another article discussed by Dr. Schloss, regarding the link between the microbiome and obesity:  “Looking for a Signal in the Noise:  Revisiting Obesity and the Microbiome.” An article from Dr. Schloss’ research team that explores a link between the human microbiome and a type of colorectal cancer. A link to the MOTHUR project, used to analyze microbiome data. A link to a video by Dr. Schloss:  “Understanding Disease Through the Lens of the Microbiome.” Dr. Schloss’ YouTube channel about data analysis. Dr. Schloss’ research group website. Dr. Schloss’ faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

    1 h y 1 min
  3. 31 OCT

    A Symphony of Cyanobacteria

    Matters Microbial #63: A Symphony of Cyanobacteria October 30, 2024 Today, Dr. Nathan Algren, Associate Professor of Biology at Clark University, joins the #QualityQuorum to discuss the centrality of cyanobacteria to our biosphere, the viruses that prey upon them, and his interests in outreach and science-oriented art. Host: Mark O. Martin Guest: Nathan Ahlgren Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of the cyanobacteria. An overview of Prochlorococcus. An overview of marine bacteriophages. The Great Oxidation Event Cyanobacteria are thought to have radically changed our planet 2.5-3.5 billion years ago by producing oxygen through photosynthesis. In essence, they and other microbes are the original terraformers. The Purple Earth Hypothesis Photosynthesis as we know it, using chlorophyll, may have evolved after another way of doing photosynthesis, with retinal that looks purple. This means that our planets and other ‘younger’ planets may look or have looked purple rather than green. Self-assembly of viral capsids, as modeled by 3D-printed parts (Art Olson) TED talk from Penny Chisholm on Prochlorococcus Co-occurring Synechococcus ecotypes occupy four major oceanic regimes defined by temperature, macronutrients and iron  Study showing how different populations of Synechococcus occupy different niches and regions of the oceans according to their adaptations to temperature and nutrients. Long-term stability and Red Queen-like strain dynamics in marine viruses  Study showing turnover of strains within relatively stable phage populations. Viral treadmills in the ocean—running to stand still  Companion ‘behind the paper’ article. Diverse Marine T4-like Cyanophage Communities Are Primarily Comprised of Low-Abundance Species Including Species with Distinct Seasonal, Persistent, Occasional, or Sporadic Dynamics  Paper showing cyanophage ‘species’ have different time patterns in the oceans. Rapid diversification of coevolving marine Synechococcus and a virus Study showing stable co-existence and co-evolution of a single Synechococcus host and phage over time. The emergence of resistance hosts and phage that overcome them demonstrate the principles of the Red Queen hypothesis and phage-host ‘arms race’. Present and future global distributions of the marine Cyanobacteria Prochlorococcus and Synechococcus Figure from this paper is in the presentation. Shows modeled distributions of Pro and Syn across the globe. They also use this to estimate a ~25% contribution of Pro and Syn to global net primary productivity in the oceans. Link to 3D prints that Dr. Ahlgren made an are available on NIH page Some resources on how to 3D protein structures: I like this guide on the practical guide of how to do actually to do it (going from PDB to print files): A link to another resource for 3D printing of protein structures. Dr. Ahlgren’s faculty website. Dr. Ahlgren’s laboratory website with many fascinating links. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

    1 h y 12 min
  4. 24 OCT

    Matters Microbial #62: Should I Stay, or Should I Go—How Bacteriophage are Released from Host Cells

    Matters Microbial #62: Should I Stay, or Should I Go—How Bacteriophage are Released from Host Cells October 23, 2024 Today, Dr. Jolene Ramsey, of the Biology Department of Texas A&M University and Affiliate of the Center for Phage Technology, joins the #QualityQuorum to discuss how bacteriophages release themselves from host cells, her efforts to teach students to work with the primary literature, and her own path to the microbial sciences.   Host: Mark O. Martin Guest: Jolene Ramsey Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A truly wonderful reminder video about bacteriophages. A link with a 3D printer design of capsid model pieces (personally, I am really interested in making one of these!). A video demonstrating how the capsid model pieces self assemble—something like real viruses can? An essential book about bacteriophage authored by my late friend Merry Youle. A fine book describing how bacteriophages can be used to fight bacterial diseases. This “first person” book by #MattersMicrobial podcast guest Steffanie Strathdee about how she was able to use bacteriophages to save her husband’s life is a must read. A link to the Citizen’s Phage Library. A link to the truly fabulous (yes, I am jealous I am not part of this program) CURE program SEA-PHAGES and SEA-GENES for undergraduate students. A remarkable illustration of T4 bacteriophage bursting from host cells by the scientist-artist David Goodsell. The organization that designed Dr. Ramsey’s laboratory logo. A link to the Clinical Genome Curation for Human Genes.   A link to the CACAO website for biocuration competition. A recent Ramsey lab mini-review on phage classification. A link to the Center for Phage Technology. The Ramsey lab Instagram page. The Ramsey lab YouTube channel. Dr. Ramsey’s laboratory website. Dr. Ramsey’s faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

    1 h y 7 min
  5. 3 OCT

    Some (Microbes) Like It Hot—Discussions with the Thermal Biology Institute

    Matters Microbial #59: Some (Microbes) Like It Hot—Discussions with the Thermal Biology Institute October 3, 2024 Today is an unusual episode of the podcast.  I am visiting four microbiologists in the Thermal Biology Institute at Montana State University of Bozeman, Montana.  They discuss their work exploring the unusual microbes and environments to be found in Yellowstone National Park, ranging from the history of the park to opportunities for undergraduate students, as well as up-to-the-minute research done on the microbial denizens of this microbiological landmark. Host: Mark O. Martin Guests (in order of appearance:): Brent Peyton, Dana Skorupa, Zackary Jay, Anthony Kohtzy Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A history and overview of Yellowstone National Park. An overview of microbiology in Yellowstone National Park. The story of Yellowstone National Park and PCR. Website for the Thermal Biology Institute. A prior podcast of #MattersMicrobial involving Dr. Roland Hatzenpichler and the research done by several of today’s guests. Dr. Peyton’s faculty website. Dr. Peyton’s laboratory website. Dr. Skorupa’s faculty website. A great article on the adventurous REU (Research Experience for Undergraduates) that Dr. Skorupa supervises. Dr. Jay’s faculty website. A journal article describing some of Dr. Jay’s (and Dr. Kohtz’) work. A page including Dr. Kohtz An article describing some of Dr. Kohtz’ (and Dr. Jay’s) work. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

    1 h y 10 min

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Matters Microbial is a podcast about the wonders of microbiology, microbiologists, and microbial centrism with Dr. Mark Martin

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