Rare Wellness Podcast (by Center for Regenerative and Performance Medicine)

Dr. Jamie Lewis
  • 5.0 (4)
  • LIFE SCIENCES
  • UPDATED BIWEEKLY

Rare Wellness Podcast (by Center for Regenerative and Performance Medicine) The Rare Wellness Podcast covers topics like regenerative medicine, longevity, hormone balance, nutrition, and supplements — offering valuable insights to help you achieve optimal health and performance. Hosted by Dr. Jamie Lewis, each episode dives into cutting-edge therapies and wellness strategies, from advanced treatments in regenerative medicine to practical tips for balancing hormones, improving nutrition, and enhancing longevity. Sponsored by Center for Regenerative and Performance Medicine, located in the beautiful Pacific Northwest, this podcast is your go-to resource for uncommon pathways to health and vitality. Wellness is rare — let’s help you find it.

  1. Progesterone: Why Optimization and Replacement Matters During Your 30s, 40s and Beyond

    4D AGO

    Progesterone: Why Optimization and Replacement Matters During Your 30s, 40s and Beyond

    Progesterone: Why Optimization and Replacement Matters During Your 30s, 40s and Beyond With Becca Pabona & Jeralee Kidd, Performance Medicine Nurses In this episode of The Rare Wellness Podcast, Performance Medicine Nurses Becca Pabona and Jeralee Kidd explore an often-overlooked but critically important hormone in women’s health: progesterone. While estrogen typically gets the spotlight in midlife conversations—especially around hot flashes and night sweats—this discussion highlights how progesterone is often the first hormone to decline during perimenopause, sometimes years before menopause begins. Becca and Jeralee break down: Why progesterone plays a key role in sleep quality, anxiety regulation, mood stability, and brain healthHow declining progesterone can lead to symptoms like insomnia (especially waking at 2–3 AM), “wired but tired” anxiety, mood swings, heavier periods, migraines, and worsening PMSThe science behind progesterone’s calming effect on the brain through the GABA-A receptor pathwayWhy micronized (bioidentical) progesterone differs significantly from synthetic progestins used in earlier hormone studiesThe importance of symptom-guided optimization, not just lab-based decision-makingWhy progesterone therapy, when used appropriately, can be one of the safest and most impactful interventionsfor perimenopausal women Jeralee also shares her personal experience with progesterone and how addressing this hormone transformed her sleep and anxiety—insights she now sees reflected in many patients at the Center for Regenerative and Performance Medicine. If you’re in your late 30s, 40s, or early 50s and feel like “something is off,” this episode may help you understand why it may not be stress or aging alone—it could be progesterone. For more information, visit www.spokaneht.com.

    6 min
  2. Why Testosterone Matters for Both Men and Women

    FEB 2

    Why Testosterone Matters for Both Men and Women

    Bhasin S, et al.Prostate Safety Events During Testosterone Replacement Therapy in Men With Hypogonadism: A Randomized Clinical Trial (TRAVERSE). JAMA Network Open. 2023;6(12):e2342583. Araujo AB, et al.Clinical review: Endogenous testosterone and mortality in men: a systematic review and meta-analysis. Journal of Clinical Endocrinology & Metabolism. 2011;96(10):3007–3019. Corona G, et al.Testosterone and metabolic syndrome: a meta-analysis study. Journal of Sexual Medicine. 2011;8(1):272–283. Davis SR, et al.Global Consensus Position Statement on the Use of Testosterone Therapy for Women. Journal of Clinical Endocrinology & Metabolism. 2019;104(10):4660–4666. Finkelstein JS, et al.Gonadal steroids and body composition, strength, and sexual function in men. New England Journal of Medicine. 2013;369:1011–1022. Rosner W, et al.Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. Journal of Clinical Endocrinology & Metabolism. 2007;92(2):405–413.

    7 min
  3. Does Testosterone Replacement Therapy Cause Prostate Cancer?

    JAN 27

    Does Testosterone Replacement Therapy Cause Prostate Cancer?

    Evidence Cited In This Episode 1. Prostate Safety and the TRAVERSE Trial (Randomized Clinical Trial) Bhasin et al. Prostate Safety Events During Testosterone Replacement Therapy in Men With Hypogonadism: A Randomized Clinical Trial — JAMA Network Open (TRAVERSE).https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2813293 2. Prostate Tissue Effects of TRT Marks et al., Effect of Testosterone Replacement Therapy on Prostate Tissue in Aging Men — JAMA 2006 (Demonstrates minimal change in prostate tissue androgen concentrations with TRT).https://www.hormonebalance.org/images/documents/Marks%2006%20Testosterone%20and%20Prostate%20cancer%20JAMA.pdf 3. Prostate Risk and Monitoring During TRT (Review) Academic review of TRAVERSE and other randomized trials summarizing prostate safety outcomes and the importance of monitoring during TRT.https://academic.oup.com/jcem/article/109/8/1975/7675461 4. Harvard Health Commentary on TRT & Prostate Cancer Risk Harvard Health Publishing: Appropriate use of testosterone therapy does not appear to raise prostate cancer risk (comments on randomized evidence showing no increased risk over ~3 years).https://www.health.harvard.edu/mens-health/appropriate-use-of-testosterone-therapy-does-not-appear-to-raise-prostate-cancer-risk

    8 min
  4. How Much Protein Do You Really Need?

    JAN 19

    How Much Protein Do You Really Need?

    How much protein do you actually need for muscle, metabolic health, and longevity—and do branched-chain amino acids (BCAAs) really matter? In this episode of the Rare Wellness Podcast, Dr. Jamie Lewis breaks down the science behind protein intake, modern research on optimal dosing, and when BCAAs are helpful—or unnecessary. While traditional protein recommendations focus on preventing deficiency, emerging research shows that optimal protein intake is significantly higher, especially for preserving muscle, metabolic health, and resilience as we age. You’ll learn: 🍽️Why muscle acts as your body’s amino acid reservoir 🍽️The difference between minimum vs optimal protein intake 🍽️Evidence-based protein targets for strength and longevity 🍽️Why spreading protein across meals matters 🍽️The role of leucine and the muscle protein synthesis “on switch” 🍽️When BCAAs make sense (and when they don’t) 🍽️Special considerations for vegetarians, older adults, fasted training, and GLP-1 medications Dr. Lewis explains why many experts now recommend 1.6–2.0 g/kg/day of protein for optimal function—and why fears around higher protein intake are largely unsupported in healthy adults. This episode provides practical, science-backed guidance to help you protect muscle, improve metabolic health, and support healthy aging without hype or extremes. 🏥 Sponsor: Center for Regenerative and Performance Medicine 🌐 Learn more at c4rpm.com 👍 If you found this episode helpful, please like, subscribe, leave a review, and share it with someone who wants to age stronger and healthier.

    6 min
  5. Creatine Explained: Muscle, Brain Health & Healthy Aging

    12/29/2025

    Creatine Explained: Muscle, Brain Health & Healthy Aging

    Creatine is often labeled as a “gym supplement,” but it is so much more. In this episode of the Rare Wellness Podcast, Dr. Jamie Lewis breaks down what creatine really is, how it works inside the body, and why it’s one of the most researched and effective supplements for muscle strength, brain health, and healthy aging. In this episode, you’ll learn: • How creatine supports muscle strength and helps combat age-related muscle loss (sarcopenia) • Why creatine may improve cognitive performance and mental resilience under stress • The truth about creatine safety, kidney health, and common myths • Evidence-based dosing strategies for performance, longevity, and recovery • How creatine fits into regenerative and performance medicine programs Creatine isn’t a replacement for good sleep, nutrition, and training—but when those foundations are in place, it can be a powerful force multiplier for long-term health and function. 🎙️ Hosted by Dr. Jamie Lewis 🏥 Sponsored by Center for Regenerative and Performance Medicine 🌐 Learn more at c4rpm.com If you found value in this episode, please like, subscribe, comment, and share to help us continue delivering evidence-based wellness insights.

    9 min
  6. What is Visceral Fat? Why It’s Dangerous & How to Reduce It

    12/22/2025

    What is Visceral Fat? Why It’s Dangerous & How to Reduce It

    🔥 Visceral fat is one of the most dangerous—and most misunderstood—forms of fat. In this episode of the Rare Wellness Podcast, host Dr. Jamie Lewis breaks down what visceral fat is, why it’s far more harmful than subcutaneous fat (what most people think of when they hear "fat"), and—most importantly—what you can do to reduce it using evidence-based strategies. You’ll learn why where fat is stored matters more than how much you weigh, and why two people with the same body weight can have completely different health risks. Key Topics Covered: • Why visceral fat drives chronic inflammation • Its link to insulin resistance and fatty liver disease • How visceral fat disrupts testosterone, estrogen, and cortisol • Why BMI alone is a poor marker of metabolic health • How to assess visceral fat (DEXA, waist circumference, labs) • Proven strategies to reduce visceral fat through sleep, exercise, nutrition, stress management, and targeted therapies The good news? Visceral fat is highly responsive to lifestyle change—and often the first fat your body burns when metabolic health improves. 🎙️ Hosted by Dr. Jamie Lewis 🌲 Sponsored by Center for Regenerative and Performance Medicine 👉 Learn more at c4rpm.com 👍 If you found this episode helpful, like, comment, and subscribe for more bite-sized insights on longevity, hormones, and regenerative medicine.

    7 min
  7. Exosomes Explained: What Actually Heals Your Body?

    12/16/2025

    Exosomes Explained: What Actually Heals Your Body?

    In this episode of the Rare Wellness Podcast, host Dr. Jamie Lewis breaks down the science behind exosomes, cutting through the hype to explain what they actually do — and what they don’t do — in regenerative medicine. Exosomes have rapidly gained attention in the wellness and orthopedic space, often advertised as injectable solutions for pain, injury, and anti-aging. But the real story is far more nuanced 🔬. Dr. Lewis explains that exosomes are biological messengers, not living cells — and that true healing requires activating your body’s own regenerative systems 🧬. 🔑 Key Takeaways from This Episode: ✅ What exosomes are and how they function as cellular “text messages” ✅ Why platelets act as your body’s first responders 🚒 ✅ The critical role of stem cells as the “general contractors” of healing 🏗️ ✅ Why exogenous (donor-derived) exosomes don’t align with how biology actually works ✅ The FDA’s position on off-the-shelf exosome products ⚠️ ✅ Why autologous regenerative therapies are biologically sound approaches Dr. Lewis uses clear analogies and real-world examples to explain why real regeneration comes from living cells responding to your specific injury, not disconnected signals from a petri dish. This episode empowers you to make informed decisions and avoid misleading regenerative medicine claims. 🌲 This episode is sponsored by the Center for Regenerative & Performance Medicine. Learn more at 👉 www. c4rpm.com 👍 If you found this episode helpful, like, comment, and subscribe to the Rare Wellness Podcast for more bite-sized insights on longevity, hormone health, and regenerative medicine.

    7 min
  8. Can GLP-1 Improve Inflammation and Pain?

    07/06/2025

    Can GLP-1 Improve Inflammation and Pain?

    ⚡️GLP-1 medications like semaglutide are best known for helping with weight loss and blood sugar—but could they also reduce inflammation and chronic pain? In this episode of the Rare Wellness Podcast, Dr. Jamie Lewis breaks down the science behind how GLP-1 receptor agonists may impact systemic inflammation, joint pain, and long-term disease risk. Whether you're managing autoimmune issues, metabolic dysfunction, or just looking to improve recovery, this episode connects the dots between GLP-1, inflammation, and regenerative health. In this episode, you’ll learn: ⚡️What GLP-1 drugs actually do in the body ⚡️The connection between metabolic health, inflammation & chronic pain ⚡️Why GLP-1s may help with arthritis, joint pain, and tissue healing ⚡️The pros, cons, and science-backed uses of GLP-1s beyond weight loss 🎧 Hosted by Dr. Jamie Lewis 🔬 Sponsored by the Center for Regenerative Medicine 🌐 Learn more: c4rpm.com and rarewellness.com 🔔 Don’t forget to like, subscribe, and share! Key Citations: • Healio Rheumatology, 2025: GLP-1 Agents Can Help Lower Systemic Inflammation (link) • Frontiers in Immunology, 2023: The Role of GLP-1 in Immune Modulation. • Diabetes Therapy, 2023: GLP-1 Receptor Agonists and Inflammatory Marker Reduction Independent of Weight Loss.

    4 min
See All (29)

Ratings & Reviews

5
out of 5
4 Ratings

About

Rare Wellness Podcast (by Center for Regenerative and Performance Medicine) The Rare Wellness Podcast covers topics like regenerative medicine, longevity, hormone balance, nutrition, and supplements — offering valuable insights to help you achieve optimal health and performance. Hosted by Dr. Jamie Lewis, each episode dives into cutting-edge therapies and wellness strategies, from advanced treatments in regenerative medicine to practical tips for balancing hormones, improving nutrition, and enhancing longevity. Sponsored by Center for Regenerative and Performance Medicine, located in the beautiful Pacific Northwest, this podcast is your go-to resource for uncommon pathways to health and vitality. Wellness is rare — let’s help you find it.

Information