From the Spectrum: Finding Superpowers with Autism

Ryan Sumner
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From the Spectrum: Finding Superpowers with Autism

I'm Ryan, and I have Autism. From the Spectrum is a podcast about Autism. I am on a mission to explain a likely cause of Autism. Autism suddenly shows up in human evolution, and it seems to be a biological adaption (neuroplasticity) to an environmental change used by living organisms for life- light. Maybe, people fail to understand how living organisms use the energy from light to drive biochemistry. In addition, I want to explain Autism. I use various scientific literature, personal experiences, and opinion. With opinion, I will explain why I feel the way I do, and give examples. I will provide links to various references for each episode. For each episode, we will discuss various aspects of Autism. Lastly, thank you for listening to From the Spectrum podcast. X: https://twitter.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum email: info.fromthespectrum@gmail.com

  1. Spindle Neurons, Salience Network, & Social Behaviors

    9 ЧЕРВ.

    Spindle Neurons, Salience Network, & Social Behaviors

    In this episode we explore spindle neurons, also known as von Economo neurons (VENs), discovered by Constantine von Economo in the 1920s. These large, cylinder-shaped cells, found in the anterior cingulate cortex (ACC), anterior (or called frontoinsula) insula, and rarely the dorsolateral prefrontal cortex (DLPFC), are crucial for rapid communication in social behaviors. Three key points stand out: first, spindle neurons are located exclusively in the ACC and insula, the core hubs of the salience network, which is disrupted in autism as early as six weeks of age, as shown in a UCLA study. Second, these neurons are primarily involved in social behaviors, underpinning complex interactions in humans and other social species. Third, they are rare, found only in highly social animals like great apes, cetaceans, and possibly elephants, highlighting their evolutionary significance. In autism, increased spindle neuron density in the insula of children aged 4–14 is linked to early brain overgrowth, though this normalizes in adulthood due to pruning. The salience network, driven by the ACC and anterior insula, relies on spindle neurons to process relevant stimuli, integrate sensory data, and guide social-emotional responses. In autism, hyper-connectivity between the insula and sensory regions causes sensory hypersensitivity, while hypo-connectivity with prefrontal areas, including the DLPFC, impairs social cognition and adaptive behaviors. This disrupts the network’s ability to switch between the default mode network and executive functions, often trapping autistic individuals in an internal world. Spindle neurons are also linked to disorders like frontotemporal dementia, schizophrenia, Alzheimer’s, and emotional dysregulation. Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism 0:00 Chroma Light Devices, use "autism" for 10% discount 3:10 Spindle Neurons; Interesting Point #1: Salience Network 6:03 Interesting Point #2: Rapid Communication & Social Behaviors 7:11 "rediscovery" of Spindle Neurons in 1990s by John Allman 8:30 Interesting Point #3: Highly Social Species 10:57 Neuropeptide Y & Monoamine- Dopamine & Serotonin 11:45 Morphology of Spindle Neurons & In Utero-Children; Social Learning 12:54 Species with Spindle Neurons 14:47 Small Clusters within the dlPFC 15:08 Salience Network, ACC, Anterior Insula; Fulcrum for Default Mode and Executive Networks 22:48 Daylight Computer Company, use "autism" for $25 discount 27:08 Diseases/Conditions associated with Spindle Neurons 29:26 The Autistic Phenotype (!!) -- The Whole Reason for the Podcast 32:25 Reviews/Ratings, Contact Info X: https://x.com/rps47586 YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    33 хв
  2. (Re-Release) Dr. Catherine Lord: The Evolution of Autism Assessment, Challenges with Understanding the Spectrum of Autism, and Barriers in the Medical and Education Systems for Autism

    3 ЧЕРВ.

    (Re-Release) Dr. Catherine Lord: The Evolution of Autism Assessment, Challenges with Understanding the Spectrum of Autism, and Barriers in the Medical and Education Systems for Autism

    In this episode, we discuss Autism with Dr. Catherine Lord. Dr. Lord is a Distinguished Professor of Psychiatry and Education at UCLA and one of the foremost researchers in Autism. Dr. Lord provides tremendous insights into her roles in Autism and Autism Assessment. Dr. Lord discusses her journey into Autism, the evolution of the Assessment including the ADOS growing from her basement and being overran by demand to the Gold Standard, the Challenges with understanding the Spectrum, updates on the Lancet Commission and Profound Autism, and Barriers in the Medical and Educational Systems. https://www.semel.ucla.edu/autism/team/catherine-lord-phd https://childmind.org/bio/catherine-lord-phd/ https://labs.dgsom.ucla.edu/lord/pages/our_team Autism and Education https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000656055638 The mention of a recent article on Predicting Profound Autism and Cell Biology and me shying away from saying "Organoids" in real-time https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11127428/ Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism (0:00) Intro (3:22) Dr. Lord's journey into Autism and Recognizing a Spectrum (11:25) The Evolution of Autism Assessment and Discussion on the ADI and ADOS- from making the ADOS in her Basement and being Overran by Demand to the Gold Standard; Revisions of Assessment Instruments (16:36) Gaps in the Autism Assessment (23:15) The Challenges with Understanding the Spectrum of Autism (29:32) Updates on the Lancet Commission and Profound Autism (35:19) Barriers with Autism and the Medical Field (39:29) Barriers with Autism and Education- Four Strikes against the Autistic Phenotype: Sensory-Processing, Speech and Language, Social Communication/Interaction, and Subject Switching (understand B3: Fixated Interests) (44:25) The Future of Autism and Helping Autistics Across the Life Span (51:03) Reviews/Ratings and Contact Info X: https://x.com/rps47586 YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    52 хв
  3. Leptin, Biophotons, & Autism's Development

    26 ТРАВ.

    Leptin, Biophotons, & Autism's Development

    In this episode, we explore the impact of tech use and blue light on circadian biology, exploring how melanopsin and chromophores regulate physiology, mood, and cell functioning. The discussion highlights the leptin-melanocortin pathway, its role in placental physiology, and how ultra-weak biophotons from placental mitochondrial DNA influence fetal development, emphasizing the critical interplay of light and dark cycles in health. We further examine fetal brain development, focusing on mitochondria, neurogenesis, and the effects of UV light and nitric oxide on the thalamus and sensory integration. The episode connects BH4, tryptophan, and melanin deficits to Autism, discussing how environmental light and electromagnetic fields disrupt biological energy, contributing to neurodevelopmental problems and the Autistic phenotype. Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism 00:00 Daylight Computer Company, use "autism" for $25 discount 04:17 leptin-melanocortin pathway, biophotons, mitochondria, POMC, nitric oxide, BH4, fetal, placental physiology, fertility, ultra-weak biophotons, maternal blood, quantum biology, melanin, UV 08:00 endocannabinoid, UV light, 380 nanometer, melanopsin, photo switch, brain development, leptin, mTOR, mitochondria, thalamus, sensory integration center, neurogenesis, fetal thalamus 12:00 nitric oxide, autism, BH4, fetal ATP production, tryptophan, cellular redox, BPA, fluoride, deuterium absorption, electromagnetic fields, semiconduction, brain growth, biological energy 16:03 Chroma Lights for Humans, use "autism" for 10% discount 20:04 leptin-melanocortin pathway, leptin, adipose tissue, melanopsin, hypothalamus, POMC, placental physiology, ultra-weak biophotons, melanin, semiconductor, antioxidant, maternal physiology, brain volume 24:23 biophotons, living cells, mitochondrial activity, cellular communication, electromagnetic waves, UV light wavelengths, energy, mitochondria, reactive oxygen species, TCA cycle, placental efficiency, thalamic timing 28:29 mitochondrial DNA, retrograde signaling, gene expression, environmental cues, autism, heteroplasmy, biophoton coherence, calcium release, acetyl coenzyme A, fetal thalamus, neurogenesis, environmental light 32:29 leptin-melanocortin pathway, neurodevelopmental problems, biophotons, somnathogenesis, circadian abnormalities, melanin, neural semiconduction, hyper excitability, hyper connectivity, salience network, attention, autistic phenotype 36:34 Reviews/Ratings, Contact Info X: https://x.com/rps47586 YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    38 хв
  4. Katie Asher: Understanding Communication, Telepathy, and Spiritual Existence

    11 ТРАВ.

    Katie Asher: Understanding Communication, Telepathy, and Spiritual Existence

    My guest today is a special Mother's Day edition with Katie Asher. Katie is a devoted mother of five and founder of Asher House, who shares her inspiring journey of raising her son Houston, who has severe autism. Katie discusses the challenges of navigating trauma, loss, and an abusive past, all while advocating for Houston’s voice through groundbreaking communication methods like letter boards. She recounts the transformative moment when Houston, previously nonverbal, began spelling to communicate, revealing his profound intelligence and telepathic abilities, which reshaped her worldview and deepened their spiritual connection. Their story, detailed in their co-authored book The Book of Heaven, highlights resilience, faith, and the fight for recognition and inclusion for non-speaking individuals. Katie also critiques systemic failures in education and healthcare, exposing how institutions often dismiss the capabilities of those with autism, prioritizing profit over humanity. She passionately advocates for presuming competence, emphasizing the need for trust, love, and proper motor coaching to unlock communication. Through her experiences, Katie calls for a societal shift toward kindness, truth, and justice, urging listeners to value every soul and embrace the spiritual abundance that fosters unity and hope. Join us for an emotional and thought-provoking conversation that challenges assumptions and celebrates the power of connection. Katie Asher X https://x.com/KTAsher5 Katie Asher Instagram https://www.instagram.com/asherhousehope/p/DHrUwDtv2R_/?img_index=1 Asher House https://www.asher.house The Book of Heaven https://www.amazon.com/dp/1737898608 DTP Hib https://en.wikipedia.org/wiki/DPT-Hib_vaccine Immune Thrombocytopenic Purpura (ITP) https://en.wikipedia.org/wiki/Immune_thrombocytopenic_purpura 0:00 Katie Asher 1:33 Katie's Intro into Autism 7;24 Challenges with the medical paradigm; Profits over Humanity 13:35 Understanding Intelligence & Communication; Telepathy & Sensory Processing 25:18 Spelling 2 Communicate 31:24 Houston Pops In 37:26 Building Trust & Communication Skills 46:19 The Instinctual Desire to be Known 48:00 Understanding Non-Verbal Communication 50:26 The Abundance Mindset 51:30 Unity through Truth & Justice 52:42 The Struggles of Parents of Autistic Children 54:10 The Role of Technology in Communication 56:36 The Challenges of Motor Control 1:00:00 Eloping & Self-Injurious Behavior; Being drawn to Water 1:02:05 The Connection to Water 1:03:50 Energy & Spiritual Connection 1:05:46 The Role of Humanity in Nature 1:07:31 The War between Nature & Machine 1:08:35 Telepathy & Communication 1:11:43 The Impact of Thoughts on Life 1:15:50 Trusting God in Doubt; Contact Information X: https://x.com/rps47586 YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    1 год 22 хв
  5. John Coates, RF Safe: The harms of non-native Electromagnetic Fields (nnEMF) and Regulations

    5 ТРАВ.

    John Coates, RF Safe: The harms of non-native Electromagnetic Fields (nnEMF) and Regulations

    My guest today is John Coates. John is the founder of RFsafe, and he is on a mission from a personal commitment to understand and educate the harms of non-native Electromagnetic Fields. John takes us through a passionate and personal story and educates us on many topics around these modern products. We explore cell phones, microwaves, routers, WIFI, computers, towers, and more. John also educates us about regulation changes such as Section 704 that prevents questioning the health factors related to our modern man-made environment. In addition, John offers a solution to the harms of WIFI by telling us about LIFI, or light fidelity. By the end of this episode, we hope you understand more about health implications related to these non-native EMFs. RF safe https://www.rfsafe.com Section 704 https://www.rfsafe.com/section-704-and-fcc-guidelines-cemented-a-dangerous-wireless-monopoly-at-the-expense-of-health-and-innovation/ FCC https://www.fcc.gov/engineering-technology/electromagnetic-compatibility-division/radio-frequency-safety/faq/rf-safety Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism 00:00 John Coates 02:20 Personal Mission & Commitment 08:14 A fight for change; Policy & Tech 11:29 Hidden Dangers of nnEMF 14:19 Unconstitutional Laws & Public Health; Protecting Big Tech 17:12 The Need for Safer Tech; Section 704 20:34 LiFI, Light Fidelity 23:20 Environment Emergency in Schools 39:37 Evolution of nnEMF & Human Health 42:31 nnEMF & Autoimmune Diseases 51:45 Bioelectric Dissonance & Development 01:03:42 The Role of Natural Environment & Health 01:12:48 The Illusion of Safety in Tech 01:16:50 Demanding Safer Tech for Children 01:21:18 Bioelectric & DNA connection theory 01:32:22 The Future of Personalized Health Solutions 01:41:00 Scams of SRA; Cancer rates X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    1 год 47 хв
  6. Dr. Reza Shadmehr: Computational Motor Control & The Cerebellum

    28 КВІТ.

    Dr. Reza Shadmehr: Computational Motor Control & The Cerebellum

    For today's episode we learn about the cerebellum with Dr. Reza Shadmehr. Dr. Shadmehr is a trailblazing neuroscientist whose groundbreaking work has reshaped our understanding of how the brain controls movement. With a rich academic journey—from a bachelor’s in electrical engineering to a PhD in robotics and computer science, followed by a postdoctoral fellowship at MIT—Dr. Shadmehr now leads the Shadmehr Lab at Johns Hopkins University. We dive into his pioneering theories, including motor memory consolidation, state space theory, and the neural encoding of action by the cerebellum’s Purkinje cells. The conversation explores the physics of motor movement, prediction, error correction, and the often-overlooked power of the cerebellum—a brain region Dr. Shadmehr calls an “underrated yet powerful” player in our daily lives. Dr. Shadmehr shares his personal path into neuroscience, sparked by a childhood fascination with the brain. This curiosity led him to blend engineering principles with biology, culminating in a lifelong mission to decode how the brain builds internal models for movement. We unpack the cerebellum’s critical role in fine-tuning actions—like stopping the tongue precisely or ensuring eye movements hit their mark, to cutting-edge research with marmosets. The episode also touches on the interplay between reward, effort, and cerebellar function, revealing surprising discoveries about how this brain region cancels noise to keep our movements smooth and purposeful. Shadmehr Lab: http://shadmehrlab.org Publications: http://shadmehrlab.org/publications YT Videos (Very Good !): https://www.youtube.com/@shadmehrlab1352 Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism 00:00 Reza Shadmehr 02:26 Daylight Computer Company, use "autism" for $25 discount 06:45 Chroma Light Devices- Lights Designed for Humans, use "autism" for 10% discount 9:54 Reza's journey into Biomedical Engineering & Neuroscience 16:26 Understanding the Cerebellum; 3 primary functions 22:07 Neuronal Communication & Purkinje Cells; Sensory and Interneurons 25:41 Cerebellum, eyes, and Autistic phenotype; Mesencephalon & other connections 28:13 Excitation/Inhibition (E/I) balance; Video examples & Movement deficiencies 29:29 Layers of the Cerebellum 34:08 E/I & Brain function 36:30 Learning & Memory in the Cerebellum 39:54 Dysfunction & Brain Compensation 41:57 Basal Ganglia and Cerebellum 43:48 Internal Calculators & Prediction 49:42 Reward & Movement & Accuracy 52:52 Movement control; Eye movements 55:56 Purkinje Cells & Tongue movements; deceleration 59:47 Understanding Language of the Cerebellum 1:01:58 Future of Cerebellar Technology X: https://x.com/rps47586 YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    1 год 4 хв

  7. 21 КВІТ.

    Autism, Sensory Map & Serotonin

    In this episode, we explore the critical role of serotonin in shaping sensory maps within the brain, a process vital for interpreting sensory input and navigating the world. Serotonin, a neurotransmitter and neuromodulator synthesized from the aromatic amino acid tryptophan, influences brain development by fine-tuning sensory systems. It modulates neuronal growth, synaptic connections, and plasticity, which are essential for creating accurate sensory maps in regions like the somatosensory cortex, visual cortex, and auditory cortex. These maps serve as blueprints for processing touch, vision, and sound, with serotonin regulating the pruning of connections in the thalamus and cortex to ensure precise sensory wiring. The episode also explores the broader biological implications of serotonin, emphasizing its role in both prenatal and postnatal development. Maternally derived serotonin, supplied via the placenta from the peripheral and enteric nervous systems, significantly influences fetal brain development, affecting proliferation, differentiation, and neuronal migration in sensory regions. Postnatally, serotonin continues to support sensory integration and mood regulation, working alongside oxytocin to facilitate bonding and stress buffering. We explore environmental factors, such as stress and modern lighting, on serotonin synthesis and the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol release. Daylight Computer Company use "autism" for $25 off at https://buy.daylightcomputer.com/RYAN03139 Chroma Iight Devices use "autism" for 10% discount at https://getchroma.co/?ref=autism 0:00 Chroma Light Devices, use "autism" for a 10% discount 03:12, Sensory Map Introduction and Serotonin’s Role, The episode introduces sensory maps, neural blueprints that help the brain interpret sensory inputs like touch, vision, and sound, 04:30, Serotonin’s Developmental Impact, Serotonin fine-tunes sensory systems by modulating neuronal growth, synaptic connections, and plasticity, creating precise sensory maps in the somatosensory, visual, and auditory cortices, 06:04, Serotonin and Sensory Processing (Visual), Serotonin, sensory processing in the visual cortex 08:29, Critical Periods and Neuroplasticity, sensory neurons and connections, pruning 10:00, Brain Regions and Serotonin’s Mechanisms, Serotonin, axonal guidance, neurogenesis, and migration via microtubules, brain-derived neurotrophic factor (BDNF), glutamate and GABA 12:55, Serotonin and Sensory Processing (Somatosensory), 13:51, Serotonin and Sensory Processing (Auditory), 14:52, Stress and the HPA Axis, Cortisol, circadian rhythms and cortisol spikes, modern environments, 16:16 Daylight Computer Company, use "autism" for a $25 discount 20:38, Maternal Serotonin and Prenatal Influence; Postnatal Serotonin and Oxytocin; Tryptophan Metabolism and Neurodevelopment, placenta, fetal brain development, proliferation, differentiation, and neuronal migration, serotonin, oxytocin & bonding and stress buffering, TPH1 and TPH2, kynurenine pathway X: https://x.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA email: info.fromthespectrum@gmail.com

    32 хв
  8. (Re-Release) Autism & Education

    17 КВІТ.

    (Re-Release) Autism & Education

    In this episode, we discuss Autism and Education. We explore some current condition within education and some personal experiences. Specifically, the school day is in complete conflict with Autism- both Criteria A and B. This is the primary factor with the challenges of Autism in Education. The classroom requires a Social Dynamic, a Speech and Language Dynamic, and Sensory-Processing Dynamic, which is 3 strikes against Autism. In addition, the subject switching throughout the school day complicates our path of learning- Our learning style prefers spending extended times on a single subject. Autism gives us the ability to be comfortable within ourselves and this accelerates our learning, our Superpowers. School and the world mostly requires the social communication and interaction. Antipsychotics https://www.marketresearchfuture.com/reports/antipsychotic-drugs-market-2784#:~:text=The%20antipsychotic%20drugs%20market%20size,period%20(2023%20%2D%202030). Pediatrician and Psychologists on the Medical Paradigm https://podcasts.apple.com/us/podcast/radically-genuine-podcast-with-dr-roger-mcfillin/id1573253801?i=1000624733618 Autism and Education https://www.fhautism.com/shop/autism-and-education-the-way-i-see-it-what-parents-and-teachers-need-to-know/ Thinking in Pictures https://www.grandin.com/inc/visual.thinking.html Autism and Intelligence and an Explanation https://www.youtube.com/watch?v=pxNg0xcadsM&t=316s (0:00) Intro; Autism and Education; Are Educators educated on Autism?; Biases from others towards the environment (7:00) The Prescription Era; Medication first Paradigm (10:32) The School Day- Conflicts with Criteria A and B; Limits a Capacity to Think; Underlying thoughts and feelings of agitation and frustration when learning; (13:15) Autism gives us the ability to be comfortable within ourselves; Are we like the so-called normal people, or not? (13:39) The Classroom- Social Dynamic, Speech and Language Dynamic, Sensory-Processing Dynamic, 3 strikes against Autism; (14:39) Subject Switching and Criteria B conflict (17:14) If you have met one child with Autism, you have met one child with Autism (17:49) Elementary School, 2 reasons why Reading is HARD, Social dynamic experience; (23:07) 4th Grade personal experience- easy task from the outside, tremendous difficulty for Autistics; (27:00) Art was fine, other subjects were not fine; Details to General versus General to Details; (27:58) High School personal experiences; Pathway to Success ＞ General Education; (29:52) Did I graduate, or Not? (31:56) SAT (32:43) Assessment Superpowers and Superdeficits- Very Superior to Severe/Impaired; Schools simply cannot accommodate to all- within group (Autistic to Autistic) or between group (Autistic to Masses) (36:34) Education Arrangement; Taking Notes is challenging (39:16) Wrap Up, Reviews, Ratings, Feedback, Contact Information

    41 хв
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Опис

I'm Ryan, and I have Autism. From the Spectrum is a podcast about Autism. I am on a mission to explain a likely cause of Autism. Autism suddenly shows up in human evolution, and it seems to be a biological adaption (neuroplasticity) to an environmental change used by living organisms for life- light. Maybe, people fail to understand how living organisms use the energy from light to drive biochemistry. In addition, I want to explain Autism. I use various scientific literature, personal experiences, and opinion. With opinion, I will explain why I feel the way I do, and give examples. I will provide links to various references for each episode. For each episode, we will discuss various aspects of Autism. Lastly, thank you for listening to From the Spectrum podcast. X: https://twitter.com/rps47586 Hopp: https://www.hopp.bio/fromthespectrum email: info.fromthespectrum@gmail.com

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