FOAMcast - Emergency Medicine Core Content FOAMcast

Prior randomized trials of convalescent plasma in COVID-19 have had disappointing results. However, these trials included patients with severe illness who were many days (if not weeks) into the course of their illness. To date, it was hypothesized, but unknown, that the benefit would be in patients very early in the course of their illness. We cover an RCT by Libster et al in NEJM on convalescent plasma in older patients with mild COVID-19.
Show notes/references: FOAMcast.org

Thanks for listening!
Lauren Westafer and Jeremy Faust

In this quick literature update we review the new recommendations from the CDC for the treatment of gonococcal infections which include:

Higher dose ceftriaxone (500 mg IM) or 1 gm IM if ≥150 kg patient
No routine azithromycin
Preference for doxycycline for co-treatment of presumed chlamydial infection

For years studies have questioned whether pulse oximeters perform as well in non-White patients as in White patients. This is particularly important now as disposition decisions in patients with COVID-19 are often made based on pulse oximetry readings.
We discussed an article by Sjoding et al in NEJM 
Show notes at FOAMcast.org
Thanks for listening!
Lauren Westafer and Jeremy Faust

Despite multiple Phase II/III vaccine trials of >30,000 participants, pregnant patients or those who are lactating have been largely excluded. In this podcast, we cover what we know (and what we don't know thus far).
The Pfizer BNT162b2 trial data submitted for FDA Emergency Use Authorization does include information on a minuscule number of patients who were immunized and became pregnant.
The Society for Maternal and Fetal Medicine has released statements on vaccines in SARS-CoV-2.
In the United Kingdom, Public Health England has released guidance for their population on vaccination in pregnancy and breastfeeding which are rooted in the lack of data.
Shownotes: FOAMcast.org
Thanks for listening!
Jeremy Faust and Lauren Westafer

We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear*
Vaccines for SARS-CoV-2 have been in development for only a few months, but several have published early results from Phase III efficacy trials in press releases. In this episode, we review these vaccines and what we know about them, and what we know about  them
Show notes (references/graphics): FOAMcast.org
Thanks for listening,
Lauren Westafer and Jeremy Faust

In this episode, we review cannabinoid hyperemesis syndrome and two recent randomized controlled trials on treatments
Haloperidol - Ruberto et al  (Annals of Emergency Medicine, In Press) Capsaicin - Dean et al. Acad Emerg Med 2020. Show notes (references, graphics) at FOAMcast.org
Thanks for listening!
Jeremy Faust and Lauren Westafer