Health & Veritas Yale School of Management

Howie and Harlan are joined by Arthur Caplan, Drs. William F. and Virginia Connolly Mitty Professor of Bioethics and founding head of the division of medical ethics at NYU Grossman School of Medicine, to discuss the ethical failings of the pharmaceutical industry and how a community-focused ethos prioritizing justice and protection of the vulnerable would have reshaped the COVID response. Harlan reports on developments in synthetic proteins. Howie recognizes World Malaria Day.
Links:
Division of Medical Ethics: NYU Langone
“‘You’ve got bad blood’: The horror of the Tuskegee syphilis experiment”
“When Evil Intrudes”
“Surgeons Perform World’s First Combined Heart Pump And Pig Kidney Transplant—Latest Breakthrough Involving Pig Organ”
“Biden trolls Trump on injecting bleach anniversary”
Frequently Asked Questions on Oregon’s Death With Dignity Act (DWDA)
“A quiet revolution in organ transplant ethics”
Center for Healthcare Ethics: The Provider-Patient Relationship
“Ex-Stanford President’s AI Drug Startup Pulls In $1 Billion in Commitments”
“Protein wrangler, serial entrepreneur, and community builder: Inside David Baker’s brain”
Baker Lab: Home Page
“Atomically accurate de novo design of single-domain antibodies”
National Cancer Institute: Definition of a Monoclonal Antibody
Malaria: World Health Organization 
CDC: Malaria’s Impact Worldwide
UNICEF: Ten things you didn’t know about malaria
Yale Innovation Summit 2024
Link for the Health & Veritas Livestream at the Yale Innovation Summit
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Howie and Harlan are joined by Scott Berkowitz ’03, cardiologist and chief population health officer at Johns Hopkins Medicine, to discuss the necessity of moving from fee-for-service to value-based care delivery to improve outcomes for all. Harlan highlights the dangers of misinformation about Ivermectin. Howie reports on the potential conflicts of interest created by device manufacturers’ payments to cardiologists.
Links:
Johns Hopkins Medicine: Home
Johns Hopkins Community Health Partnership
“Association of a Care Coordination Model With Health Care Costs and Utilization”
“Planning for the Future of Population Health: The Johns Hopkins Medicine Experience”
“Califf’s long day on Capitol Hill”
“The FDA Deleted Its Viral Ivermectin Tweets. Now There’s Even More Misinformation.”
“Philly Nonprofit Awarded $48 Million to Apply AI in Search for New Uses for Approved Drugs
Posted on March 12, 2024”
“Effect of Early Treatment with Ivermectin among Patients with Covid-19”
“Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19”
“Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19”
“Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype”
Ivermectin and Covid
“FDA settles lawsuit over ivermectin content that doctors claimed harmed their practice”
“Intravascular Microaxial Left Ventricular Assist Device Manufacturer Payments to Cardiologists and Use of Devices”
“Impact of Industry Payments on Prescribing Patterns for Tumor Necrosis Factor Inhibitors Among Medicare Beneficiaries”
Yale Innovation Summit 2024
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Howie and Harlan are joined by Atheendar Venkataramani, a physician, health economist, and director of the Perelman School of Medicine’s Opportunity for Health Lab, to discuss the powerful role of economic opportunity in population health outcomes. Harlan reports on two studies where treatments’ unexpected benefits leapt ahead of understanding why they work. Howie reflects on the business model of the pharma industry and the market reaction to anti-obesity drugs.
Links:
Opportunity for Health | Home
“College Affirmative Action Bans and Smoking and Alcohol Use among Underrepresented Minority Adolescents in the United States: A Difference-in-differences Study”
“Police Killings and Their Spillover Effects on the Mental Health of Black Americans: A Population-based, Quasi-experimental Study”
“Officer-Involved Killings of Unarmed Black People and Racial Disparities in Sleep Health“
Behavioral Risk Factor Surveillance System | Home
“Building Black Wealth — The Role of Health Systems in Closing the Gap“
KFF | Understanding Mergers Between Hospitals and Health Systems in Different Markets
“In Hospitals, Affordable Housing Gets the Long-Term Investor It Needs”
American College of Cardiology 73rd Annual Scientific Session & Expo 
“Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes“
“Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): a randomised, placebo-controlled trial”
“A Placebo-Controlled Trial of PCI for Stable Angina“
“Trial of Lixisenatide in Early Parkinson’s Disease“
“The Cream of The Crop: 5 Biotechs That Outrank Most Stocks”
“How High Can Eli Lilly Stock Go? $1,000 A Share, One Analyst Says”
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Howie and Harlan are joined by Kate McEvoy, executive director of the National Association of Medicaid Directors, to discuss the programs’ underappreciated advances in holistically addressing health, housing, and food security. Reflecting on the upcoming election, Harlan notes that facts matter, whether in medicine or politics. Howie reports on the dangers of glyoxylic acid in hair straightening products.
Links:
“Trump Leads Biden in Six of Seven Swing States, WSJ Poll Finds”
“Takeover: Hitler’s Final Rise to Power”
“The Forgotten History of Hitler’s Establishment Enablers”
The Future of Health Policy in a Partisan United States
“Netflix blockbuster ‘3 Body Problem’ divides opinion and sparks nationalist anger in China”
“The Future of American Democracy Depends on Improving U.S. Health”
Wikipedia | Glyoxylic acid
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid
American Cancer Society | Formaldehyde and Cancer Risk
Kaiser Family Foundation | 10 Things to Know About the Unwinding of the Medicaid Continuous Enrollment Provision
Kaiser Family Foundation | Medicaid Postpartum Coverage Extension Tracker
CMS | NHE Fact Sheet
Moral Injuries in Healthcare Workers: What Causes Them and What to Do About Them?
NCDHHS | Healthy Opportunities Pilots
HealthTech4Medicaid | About
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Howie and Harlan are joined by Margo Harrison, an OB-GYN and femtech entrepreneur, to discuss how innovative solutions to women’s health problems offer deeper understanding and expanded choices. Harlan and Howie each offer a caveat emptor for lightly regulated, unproven supplements and treatments such as Prevagen and hydration spas.
Links:
“Prevagen Review: A Word of Caution”
“Prevagen®: Analysis of Clinical Evidence and Its Designation as a ‘#1 Pharmacist Recommended Brand’”
“NY Jury Rules Some Claims About Prevagen Are Misleading”
“Effects of a Supplement Containing Apoaequorin on Verbal Learning in Older Adults in the Community”
Mate Fertility: Home
Dahlia Ventures
Margo Harrison, MD: Assistant Adjoint Professor, OB-GYN-Basic Repro Science
Margo Harrison: LinkedIn
“Use of Cesarean Birth at Mizan Tepi University Teaching Hospital, Mizan Aman, Ethiopia”
“Postpartum Contraceptive Use Among Denver-Based Adolescents and Young Adults: Association with Subsequent Repeat Delivery”
“Warnings grow about risky IV drips and injections at unregulated med spas”
“FDA highlights concerns with compounding of drug products by medical offices and clinics under insanitary conditions”
“Drip bar: Should you get an IV on demand?”
“Are Your Therapies FDA Compliant?”

Howie and Harlan are joined by Yale health economist Zack Cooper to discuss his work on surprise medical bills and the impact of high healthcare costs on households, wages, and the economy. Harlan reports on Hippocratic AI’s efforts to develop AI nurses. Howie looks at the global effort to eradicate tuberculosis.
Links:
“Hippocratic AI banks $53M backed by General Catalyst, a16z, Memorial Hermann, UHS and other health systems”
“Polaris: A Safety-focused LLM Constellation Architecture for Healthcare”
Yale | Eli Whitney Students Program
Touching the Dragon: And Other Techniques for Surviving Life’s Wars
The Price Ain’t Right? Hospital Prices and Health Spending on the Privately Insured
“Costs Can Go Up Fast When E.R. Is in Network but the Doctors Are Not”
“Bankrupt Envision Healthcare approved to split in two, cut debt”
“The Company Behind Many Surprise Emergency Room Bills”
Surprise! Out-of-Network Billing for Emergency Care in the United States
“Medical LLM developer Hippocratic AI gets $53M at $500 valuation”
The Breakthrough of Large Language Models Release for Medical Applications: 1-Year Timeline and Perspectives
World Health Organization | World Tuberculosis Day
Partners In Health | Tuberculosis
“WHO urges investments for the scale up of tuberculosis screening and preventive treatment”
“The latest twist in John Green’s anti-tuberculosis story: working with governments”
Learn more about the MBA for Executives program at Yale SOM.
Email Howie and Harlan comments or questions.