Medscape InDiscussion: Psoriasis Medscape

Dr Steven Feldman and Leah Howard, National Psoriasis Foundation President and CEO, discuss how an unseen and unheard patient population has begun to step out and speak up — at the US Capitol and beyond.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986130). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
National Psoriasis Foundation (NPF) https://www.psoriasis.org/
Management of Psoriasis as a Systemic Disease: What Is the Evidence? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187293/
Psoriasis: Classical and Emerging Comorbidities https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323693/

Dr Steve Feldman speaks with Drs Mehta, Ritchlin, and Fried who share an exciting new roadmap for calming key psoriasis comorbidities.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986151). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Treatment of Psoriasis With Biologic Therapy Is Associated With Improvement of Coronary Artery Plaque Lipid-rich Necrotic Core: Results From a Prospective, Observational Study https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.120.011199
Treating the Skin With Biologics in Patients With Psoriasis Decreases the Incidence of Psoriatic Arthritis https://pubmed.ncbi.nlm.nih.gov/34281904/
The Patient Health Questionnaire-2: Validity of a Two-Item Depression Screener https://pubmed.ncbi.nlm.nih.gov/14583691/

Drs Steven R. Feldman and Kim A. Papp discuss the expanding universe of opportunities and advances for halting limited psoriasis.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986152). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Trial of Roflumilast Cream for Chronic Plaque Psoriasis https://pubmed.ncbi.nlm.nih.gov/32668113/
Psoriasis in Special Localizations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330687/
Vitamin D Analogs in the Treatment of Psoriasis: Where Are We Standing and Where Will We Be Going? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219168/

Dr Steven R. Feldman and nurse practitioner Lakshi M. Aldredge discuss systemic therapy for psoriasis and how nurse practitioners and physician associates fill an important gap.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986153). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199465/?report=reader
Tumor Necrosis Factor Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK482425/
Deucravacitinib for the Treatment of Psoriatic Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372960/

Drs Steve Feldman and Andrew Blauvelt have a fascinating chat about contrasts and similarities between biologics and biosimilars, covering pharmacoeconomic and legal differences between the US and Europe.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986154). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Biosimilar Drugs for Psoriasis: Principles, Present, and Near Future https://pubmed.ncbi.nlm.nih.gov/29549597/
International Psoriasis Council https://psoriasiscouncil.org/
Biosimilars for Psoriasis: Clinical Studies to Determine Similarity https://pubmed.ncbi.nlm.nih.gov/27639072/
Safety, Efficacy and Drug Survival of Biologics and Biosimilars for Moderate-to-severe Plaque Psoriasis https://pubmed.ncbi.nlm.nih.gov/29094341/

Drs Steve Feldman and Megan Noe fill in the gaps about pustular psoriasis, a relatively rare but serious condition that can be tough to diagnose.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/986155). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Palmoplantar Pustulosis: Current Understanding of Disease Definition and Pathomechanism https://pubmed.ncbi.nlm.nih.gov/32201085/
Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655659/
Pathophysiology of Generalized Pustular Psoriasis https://pubmed.ncbi.nlm.nih.gov/36779688/
Trial of Spesolimab for Generalized Pustular Psoriasis https://pubmed.ncbi.nlm.nih.gov/34936739/