Babbage from The Economist

Babbage from The Economist

Babbage is our weekly podcast on science and technology, named after Charles Babbage—a 19th-century polymath and grandfather of computing. Host Alok Jha talks to our correspondents about the innovations, discoveries and gadgetry shaping the world. Published every Wednesday. If you’re already a subscriber to The Economist, you’ll have full access to all our shows as part of your subscription. For more information about Economist Podcasts+, including how to get access, please visit our FAQs page here https://myaccount.economist.com/s/article/What-is-Economist-Podcasts

  1. 22 JAN • SUBSCRIBERS ONLY

    Chromosome 21: the surprising link between Down’s syndrome and Alzheimer’s

    Since the 1980s, the average life expectancy of a person with Down’s syndrome has more than doubled, from less than 30 to well into their 60s. Living longer, though, has revealed a tragic twist—the vast majority of people with Down’s will go on to develop Alzheimer’s disease by the age of 65. That’s because people with Down's syndrome, who have an extra copy of chromosome 21, produce increased amounts of beta-amyloid, a protein that is implicated as a possible cause of Alzheimer’s. To make things worse, people with Down’s syndrome often cannot access the dementia drugs that might help them—doctors are reluctant to prescribe them because people with Down’s haven't been allowed to take part in the clinical trials for Alzheimer’s drugs. People with Down’s think that should change. In doing so, could scientists unlock the mystery of Alzheimer’s itself? Alok Jha, The Economist’s science and technology editor and Emilie Steinmark, our science correspondent, follow the story of Kate Olmstead, who has Down’s syndrome, and her mother, Amy. Emilie also interviews John Hardy, a neuroscientist at University College London who proposed the amyloid hypothesis for Alzheimer’s in the 1990s. Thanks also to Frank Stephens of the Global Down Syndrome Foundation. Transcripts of our podcasts are available via economist.com/podcasts. Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

    40 min
  2. 15 JAN • SUBSCRIBERS ONLY

    Gary Marcus: a sceptical take on AI in 2025

    From the release of AI agents to claims that artificial general intelligence has (finally!) been achieved, 2025 will probably be another blockbuster year for AI. That sense of continuous progress is not shared by everyone, however. Generative AI, based on large language models (LLMs), struggles with reasoning, reliability and truthfulness. While progress has been made in those domains, sceptics argue that the limitations of LLMs will fundamentally restrict the future of AI. In this episode, Alok Jha, The Economist’s science and technology editor, interviews Gary Marcus, one of modern AI’s most energetic critics. They discuss what to expect in 2025 and why Gary is pushing for researchers to work on a much wider range of scientific ideas (in other words, beyond deep learning) to enable AI to reach its full potential. Gary Marcus is a professor emeritus in cognitive science at New York University and the author of “Taming Silicon Valley”, a book advocating for a more responsible approach to the development of AI. For more on this topic, check out our series on the science that built the AI revolution, as well as our episodes on AGI. Transcripts of our podcasts are available via economist.com/podcasts. Listen to what matters most, from global politics and business to science and technology—subscribe to Economist Podcasts+. For more information about how to access Economist Podcasts+, please visit our FAQs page or watch our video explaining how to link your account.

    37 min

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About

Babbage is our weekly podcast on science and technology, named after Charles Babbage—a 19th-century polymath and grandfather of computing. Host Alok Jha talks to our correspondents about the innovations, discoveries and gadgetry shaping the world. Published every Wednesday. If you’re already a subscriber to The Economist, you’ll have full access to all our shows as part of your subscription. For more information about Economist Podcasts+, including how to get access, please visit our FAQs page here https://myaccount.economist.com/s/article/What-is-Economist-Podcasts

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