American Journal of Psychiatry Audio American Journal of Psychiatry

Dr. Mark D. Shen (University of North Carolina, Chapel Hill) discusses the trajectory of brain development in infants at risk for autism spectrum disorder (ASD) and fragile X syndrome.  Longitudinal imaging was captured from 6 to 24 months to see how brain development differed between groups, and the development of the amygdala in infants at risk for ASD prior to onset of social deficits and clinical diagnosis.
Shen interview [01:03] Why look at patients with potential ASD diagnosis in conjunction with fragile X syndrome patients? [04:20] Why are differences in brain structure important? [05:46] What’s the advantage of earlier diagnosis of ASD? [08:16] What’s next for your research? [09:48] Kalin interview [11:47] Shen et al. [12:09] Girault et al. [15:30] Gerlach et al. [19:13] Mosholder et al. [22:12] Summary [25:31] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Transcript
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Watch Deputy Editor Daniel S. Pine, M.D., present highlights from the August 2022 issue of AJP.
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Dr. Richard S.E. Keefe (Duke University Medical Center, Durham, North Carolina) discusses an article looking at an intervention for major depressive disorder that takes the form of a videogame. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the July issue’s theme.
Keefe interview: [01:00] What were your results? [03:13] What do videogames offer as a depression intervention? [03:43] Differences between the intervention and the control intervention [05:05] What was the impact of the interventions? [06:51] What were the limitations of the design and what might change going forward? [08:10] Does the patient’s perception of the effectiveness of the intervention matter? [09:20] How the intervention differs from a similar intervention aimed at children [10:19] Is there an advantage to “hiding” the intervention as a videogame? [11:33] Designing a game and an intervention that work simultaneously [13:27] What next for your research? [15:05] Kalin interview [16:11] Keefe et al. [16:22] Tabuteau et al. [18:15] Ge et al. [20:54] Pan et al. [22:01] Tamm et al. [23:47] Pizzagalli [25:30] Grogans et al. [26:02] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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AJP Editor-in-Chief Dr. Ned Kalin discusses the June issue with guest editor Dr. Crystal Barksdale (National Institute on Minority Health and Health Disparities). The issue focuses on mental health disparities, the pervasive negative consequences of structural racism, and the importance of community-wide and systemic interventions.
Barksdale interview [00:30] How do mental health disparities differ for minoritized groups? [04:10] Structural and institutional racism as a factor in mental health disparities [05:53] Why have structural factors been largely ignored? [08:37] Alvidrez and Barksdale [11:03] Alegria et al. [13:11] Keeping review committees and reviewers up to date [15:11] Hankerson et al. [16:53] Developing research strategies based on the needs of the community [18:09] Alvarez et al. [20:22] What can the journal do to push these issues forward? [22:19]  
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Kenneth Kendler (Virginia Institute for Psychiatric and Behavioral Genetics at Virginia Commonwealth University, Roanoke, VA) discusses the history and emergence of psychiatry as a discipline, and how the conception of mind, body, and soul evolved. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses the May issue of AJP, and the past, present, and future of psychiatry.
Kendler interview [00:45] Why is it important to look at the history of psychiatry? [10:28] The emergence of mental asylums [12:58] The mixed legacy of asylums [16:24] What’s next? [18:07] Kalin interview [21:14] Brennand [23:07] Erwin and Weinberger, Cruceanu et al. [24:29] Pretzsch et al. [26:04] Roberts et al. [27:17] Meier et al. [28:52] Pedersen et al. [32:02] In conclusion [33:55] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Brian Kelly (Purdue University, West Lafayette, Indiana) discusses a study that found recent efforts to curb opioid prescriptions appear to have had an effect on reducing prescription opioid misuse and dependence, with no evidence that shifts in local-level opioid dispensing affected odds of heroin use, frequency of heroin use, or heroin dependence. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses what pulls the March issue of AJP together.
Kelly interview [00:30] Why county level data? [01:22] What accounts for the variation between counties? [02:28] Decreased prescription rates did not lead to increased heroin usage [04:07] How do we ensure the needs of those who need pain management? [04:55] What should happen with opioid dispensing practices? [06:10] National Survey on Drug Use and Health [07:30] Next steps [08:35] Kalin interview [09:34] Vuolo and Kelly [09:58] Watts et al. [11:25] O’Keeffe et al. [14:25] Sohal [17:35] Chung et al. [18:35] Summary [23:05] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Giovanna Punzi and Dr. Daniel Weinberger (Lieber Institute for Brain Development, Baltimore, Maryland) discuss findings from their new paper, “Genetics and Brain Transcriptomics of Completed Suicide,” which looks at differences in the brains of those who die by violent versus less violent means of suicide.  Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses what pulls the March issue of AJP together.
Punzi and Weinberger interview [00:43] What made the two categories distinct? [02:28] Aggression as a factor [03:43] Differences in genetic factors [04:58] Potential heterogeneity of suicide [06:28] Counterintuitive conclusions [07:42] Clinical implications for those at risk for suicide [11:00] Next steps for research [11:43] Kalin interview [12:56] McMahon [13:58] Jacquemont et al. [14:22] Mancini et al. [15:53] Mahjani et al. [18:40] Leckman [21:22] Punzi et al. [21:48] Ecker et al. [25:38] Summary [28:45]  
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on Twitter.
E-mail us at ajp@psych.org