Chapter Thirteen: The Meaning and Application of Urine Chemistries

References

JC mentioned that the diagnostic accuracy of 24 hour urine collection increases with more collections! Metabolic evaluation of patients with recurrent idiopathic calcium nephrolithiasis

We didn't refer to a particular study on sodium intake and the 24 hour urine but this meta-analysis Comparison of 24‐hour urine and 24‐hour diet recall for estimating dietary sodium intake in populations: A systematic review and meta‐analysis - PMC 24‐hour diet recall underestimated population mean sodium intake.

Anna looking up ace i and urinary sodium Effects of ACE inhibition on proximal tubule sodium transport | American Journal of Physiology-Renal Physiology

The original FENa paper by Espinel: The FeNa Test: Use in the Differential Diagnosis of Acute Renal Failure | JAMA | JAMA Network

Schreir’s replication and expansion of Espinel’s data: Urinary diagnostic indices in acute renal failure: a prospective study

Here’s a report from our own JC on the Diagnostic Utility of Serial Microscopic Examination of the Urinary Sediment in Acute Kidney Injury | American Society of Nephrology

JC shared his journey regarding FENa and refers to his recent paper Concomitant Identification of Muddy Brown Granular Casts and Low Fractional Excretion of Urinary Sodium in AKI

And Melanie’s accompanying editorial Mind the Cast: FENa versus Microscopy in AKI : Kidney360 (with a great image from Samir Parikh)

JC referenced this study from Schrier on FENa with a larger series: Urinary diagnostic indices in acute renal failure: a prospective study

​​Nonoliguric Acute Renal Failure Associated with a Low Fractional Excretion of Sodium | Annals of Internal Medicine

Urine sodium concentration to predict fluid responsiveness in oliguric ICU patients: a prospective multicenter observational study | Critical Care | Full Text

A classic favorite: Acute renal success. The unexpected logic of oliguria in acute renal failure

 Marathon runners had granular casts in their urine without renal failure. Kidney Injury and Repair Biomarkers in Marathon Runners

Cute piece from Rick Sterns on urine electrolytes! Managing electrolyte disorders: order a basic urine metabolic panel

The Urine Anion Gap: Common Misconceptions | American Society of Nephrology

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