Dr. Siyu Shi: Investor at F-Prime & Healthcare Venture Capital

In this episode, our guest is Dr. Siyu Shi, MD, MBA. Dr. Shi is an investor at venture capital firm F-Prime Capital. She has over 10 portfolio companies, across healthcare sub sectors including MedTech, IT, and therapeutics, in which she led or co-led the investment. She also collaborates with Eight Roads, F-Prime’s sister company, based in Asia to work with Chinese startups. She talks about her experience both as an internal operator and an outside investor and why she ultimately chose F-Prime. This episode ought to be of interest to anyone interested in becoming a physician entrepreneur and in understanding how a hard science background can be useful for a career in finance.

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This episode was hosted and edited by David Park.

Timestamps

(01:10) Why choose a business career over residency?

(02:25) Working as a founder vs. investor

(03:40) Transferable skills of science to venture capital investing

(05:10) F-Prime’s investment capabilities and range

(06:04) Eight Roads and working with Chinese startups

(07:59) Sourcing startups

(08:40) F-Prime’s differentiator within the VC industry

(09:51) AI hype

(11:11) Engrail Therapeutics: most recent investment

(13:10) Startup accelerators at Stanford

(15:52) Assessing entrepreneurial DNA

(16:44) IPO successes

(19:02) Advice for future investors and founders

(19:55) Weightlifting