Empowered Patient Podcast

Karen Jagoda
  • 4.9 (16)
  • MEDICINE
  • UPDATED DAILY
Empowered Patient Podcast

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

  1. 1 DAY AGO

    Robust Cybersecurity Risk Management in the Healthcare Ecosystem with George Pappas Intraprise Health TRANSCRIPT

    George Pappas, CEO of Intraprise Health, works with various healthcare organizations across the healthcare industry and healthcare ecosystem to help address cybersecurity risks. While recent cyber attacks have raised awareness about the need for better cybersecurity measures, the complexity of healthcare IT systems creates significant challenges for comprehensive risk management. Proactive measures, including employee training, enhanced identity confirmation, and limiting access, are critical to mitigating the risk of cyber attacks.   George explains, "The net situation is that these large technology companies that serve healthcare and hospital systems and large medical practices change are clearinghouses, revenue cycle managers, and manage real-time price transparency. What medication management companies manage is so complicated, and they have so many ways that something can be attacked. As you mentioned at the beginning, the attackers are getting very clever and sharing a lot of their methods, so you have to do a comprehensive continuous review of your entire cybersecurity posture. Because if you don’t, there are invariably going to be challenges and small things that are small at the time that end up not being small and being the way that an attacker got in." "And in the case of Change, it was a multifactor authentication problem accessing a certain system through a certain technology stack that was rather old. But these things exist in companies this size. They have tens of thousands of machines and have accumulated different companies they acquired over time with different technology systems that don’t all work together. So, the vulnerabilities are there, and they require comprehensive risk management and some candidly, more investment than we’ve seen to address fully." "I’ll give you another example. So maybe it helps your listeners place this a little better. If you think about someone who has a home and is trying to protect their home from all the various threats or things that can happen. Well, their home insurance company requires them to have a smoke detector and carbon monoxide sensor. They get a credit on their policy. If they have a burglar alarm system, they might have a ring doorbell camera or any number of things like that. What you see across the industry is these large hospital systems, small hospital systems, doctor’s offices, and they’re doing those basic things. But here’s the issue. In that same house that I mentioned, you could have 30 windows, the roof might be a little old, you might have a ground floor, and a door that has glass could be easily broken if someone tried to break in." #IntrapriseHealth #HealthcareCybersecurity #PatientDataProtection #CyberThreats #HITRUSTCompliance #RiskManagement #DataPrivacy intraprisehealth.com Listen to the podcast here

  2. 1 DAY AGO

    Robust Cybersecurity Risk Management in the Healthcare Ecosystem with George Pappas Intraprise Health

    George Pappas, CEO of Intraprise Health, works with various healthcare organizations across the healthcare industry and healthcare ecosystem to help address cybersecurity risks. While recent cyber attacks have raised awareness about the need for better cybersecurity measures, the complexity of healthcare IT systems creates significant challenges for comprehensive risk management. Proactive measures, including employee training, enhanced identity confirmation, and limiting access, are critical to mitigating the risk of cyber attacks.   George explains, "The net situation is that these large technology companies that serve healthcare and hospital systems and large medical practices change are clearinghouses, revenue cycle managers, and manage real-time price transparency. What medication management companies manage is so complicated, and they have so many ways that something can be attacked. As you mentioned at the beginning, the attackers are getting very clever and sharing a lot of their methods, so you have to do a comprehensive continuous review of your entire cybersecurity posture. Because if you don’t, there are invariably going to be challenges and small things that are small at the time that end up not being small and being the way that an attacker got in." "And in the case of Change, it was a multifactor authentication problem accessing a certain system through a certain technology stack that was rather old. But these things exist in companies this size. They have tens of thousands of machines and have accumulated different companies they acquired over time with different technology systems that don’t all work together. So, the vulnerabilities are there, and they require comprehensive risk management and some candidly, more investment than we’ve seen to address fully." "I’ll give you another example. So maybe it helps your listeners place this a little better. If you think about someone who has a home and is trying to protect their home from all the various threats or things that can happen. Well, their home insurance company requires them to have a smoke detector and carbon monoxide sensor. They get a credit on their policy. If they have a burglar alarm system, they might have a ring doorbell camera or any number of things like that. What you see across the industry is these large hospital systems, small hospital systems, doctor’s offices, and they’re doing those basic things. But here’s the issue. In that same house that I mentioned, you could have 30 windows, the roof might be a little old, you might have a ground floor, and a door that has glass could be easily broken if someone tried to break in." #IntrapriseHealth #HealthcareCybersecurity #PatientDataProtection #CyberThreats #HITRUSTCompliance #RiskManagement #DataPrivacy intraprisehealth.com Download the transcript here

    18 min

  3. 1 DAY AGO

    Developing Non-Opioid Pain Medication with Reduced Abuse Potential with Ketan Mehta Tris Pharma TRANSCRIPT

    Ketan Mehta, Founder and CEO of Tris Pharma, is focused on developing non-addictive pain medication. Their lead drug candidate is designed to be an effective pain drug without the respiratory-depressive and addictive side effects of traditional opioid drugs. This drug works by targeting the nociceptin receptor and has also shown promise to help curb cravings and dependence on opioids. The goal is to provide doctors and patients with a non-opioid pain medication option that can help reduce reliance on highly addictive prescription opioids.  Ketan explains, "Tris is focused on neuroscience-based products, especially CNS, at a high level. More specifically, we focused on ADHD and neurodevelopmental disorders and the products that treat them. And also, more recently, we have been more active in the pain space." "We're developing a drug, which is currently an investigational drug in Phase three clinical trials. It's called cebranopadol. And what we have seen is that it has an efficacy just on par with your typical traditional opioid. It’s highly effective from what we have seen in more than 2,000 patients to date. But also, what we're seeing thus far is that there is no indication that it creates dependency. You can just taper off the patients, meaning you don't have to give lesser dose even after pain has subsided. And it does not give you the level of respiratory depression or failure that we see with the traditional opioid." "Right now, we're conducting our first trials in acute pain, and then we will look at any kind of moderate to severe pain. Essentially like chronic pain, lower back pain, for example, the pain in arthritis, cancer pain, other disease conditions like fibromyalgia, or just any kind of injury that gives you pretty much any nociceptive pain that one would encounter, we expect, like diabetic peripheral neuropathy and so forth." #TrisPharma #PainManagement #ClinicalTrial #Innovation #PainTherapy #Cebranopadol  trispharma.com Listen to the podcast here

  4. 1 DAY AGO

    Developing Non-Opioid Pain Medication with Reduced Abuse Potential with Ketan Mehta Tris Pharma

    Ketan Mehta, Founder and CEO of Tris Pharma, is focused on developing non-addictive pain medication. Their lead drug candidate is designed to be an effective pain drug without the respiratory-depressive and addictive side effects of traditional opioid drugs. This drug works by targeting the nociceptin receptor and has also shown promise to help curb cravings and dependence on opioids. The goal is to provide doctors and patients with a non-opioid pain medication option that can help reduce reliance on highly addictive prescription opioids.  Ketan explains, "Tris is focused on neuroscience-based products, especially CNS, at a high level. More specifically, we focused on ADHD and neurodevelopmental disorders and the products that treat them. And also, more recently, we have been more active in the pain space." "We're developing a drug, which is currently an investigational drug in Phase three clinical trials. It's called cebranopadol. And what we have seen is that it has an efficacy just on par with your typical traditional opioid. It’s highly effective from what we have seen in more than 2,000 patients to date. But also, what we're seeing thus far is that there is no indication that it creates dependency. You can just taper off the patients, meaning you don't have to give lesser dose even after pain has subsided. And it does not give you the level of respiratory depression or failure that we see with the traditional opioid." "Right now, we're conducting our first trials in acute pain, and then we will look at any kind of moderate to severe pain. Essentially like chronic pain, lower back pain, for example, the pain in arthritis, cancer pain, other disease conditions like fibromyalgia, or just any kind of injury that gives you pretty much any nociceptive pain that one would encounter, we expect, like diabetic peripheral neuropathy and so forth." #TrisPharma #PainManagement #ClinicalTrial #Innovation #PainTherapy #Cebranopadol  trispharma.com Download the transcript here

    19 min

  5. 2 DAYS AGO

    Proactive Management of Chronic GI Conditions with Beth Houck SonarMD TRANSCRIPT

    Beth Houck, Chief Executive Officer at SonarMD, works with payers and physician practices to provide proactive, value-based care for patients with chronic GI conditions. They use a digital platform to monitor self-reported patient symptoms and enable physicians to identify those patients that need attention. This approach aims to improve patient outcomes and reduce emergency room visits and hospitalizations.   Beth explains, "SonarMD manages patients with chronic gut health conditions, and specifically, we started with something called inflammatory bowel disease, which is the encompassing word for patients with Crohn's and ulcerative colitis. We develop a value-based contract with a payer, so somebody at risk for the cost of care of a patient, and then we bring that cost of care program to a physician's office. In collaboration with that physician, we manage a population of patients to have better outcomes for their chronic GI conditions." "We just talk about this as a shift to proactive care from reactive care. So rather than the loudest patients being seen, we will have patients that we surface as the most important patients for them to see. So we reach out to our patients and do it very lightly with a text message or email. We tell them a little bit about the program. We talk to them about how we're doing this on behalf of their physician practice and in collaboration with them. So this isn't something that's being forced on you by a payer. We ping those patients, which is the term we use on a regular basis, to collect their reported outcomes or the symptoms they're having with their disease."  #SonarMD #DigitalHealth #Healthcare #VBC #ValuebasedCare #GI #IBD SonarMD.com Listen to the podcast here

  6. 2 DAYS AGO

    Proactive Management of Chronic GI Conditions with Beth Houck SonarMD

    Beth Houck, Chief Executive Officer at SonarMD, works with payers and physician practices to provide proactive, value-based care for patients with chronic GI conditions. They use a digital platform to monitor self-reported patient symptoms and enable physicians to identify those patients that need attention. This approach aims to improve patient outcomes and reduce emergency room visits and hospitalizations.   Beth explains, "SonarMD manages patients with chronic gut health conditions, and specifically, we started with something called inflammatory bowel disease, which is the encompassing word for patients with Crohn's and ulcerative colitis. We develop a value-based contract with a payer, so somebody at risk for the cost of care of a patient, and then we bring that cost of care program to a physician's office. In collaboration with that physician, we manage a population of patients to have better outcomes for their chronic GI conditions." "We just talk about this as a shift to proactive care from reactive care. So rather than the loudest patients being seen, we will have patients that we surface as the most important patients for them to see. So we reach out to our patients and do it very lightly with a text message or email. We tell them a little bit about the program. We talk to them about how we're doing this on behalf of their physician practice and in collaboration with them. So this isn't something that's being forced on you by a payer. We ping those patients, which is the term we use on a regular basis, to collect their reported outcomes or the symptoms they're having with their disease."  #SonarMD #DigitalHealth #Healthcare #VBC #ValuebasedCare #GI #IBD SonarMD.com Download the transcript here

    18 min

  7. 3 DAYS AGO

    How Generative AI is Unlocking Insights to Expand Drug Development with Dr. Chris Bouton Certara TRANSCRIPT

    Dr. Chris Bouton, the Senior VP and Head of Artificial Intelligence at Certara, is exploring applying generative AI to drug discovery and development to improve efficiency and identify novel therapeutics across various use cases. The focus is on developing specialized secure AI models to integrate internal data with the Certara platform. Generative AI is particularly useful in areas with high specificity, such as antibody design and mRNA therapeutics, where modeling the underlying biology is crucial.  Chris explains, "Certara helps pharmaceutical and biotech companies throughout their process, from early basic research to regulatory filing and beyond. And we're quite a unique company in that we are not developing our own drugs but instead helping companies develop their drugs. And it's something like over 90% of all FDA approvals are projects that, in some way, shape, or form, Certara has helped with." "Our philosophy is to start with the use case. Generative AI is an incredible novel technology. There are many different ways to apply it, but we're interested in how to turbocharge or otherwise ameliorate and create efficiencies in a wide range of the use cases that Certara works on. What we're doing is taking a look at each of those kinds of use cases, trying to identify whether generative AI is useful in those use cases. Then, build out technology-driven solutions that are a combination of gen AI plus services, plus data, plus other software for each of those use cases." #Certara #GenerativeAI #HealthAI #DrugDiscovery #DrugDevelopment certara.com Listen to the podcast here

  8. 3 DAYS AGO

    How Generative AI is Unlocking Insights to Expand Drug Development with Dr. Chris Bouton Certara

    Dr. Chris Bouton, the Senior VP and Head of Artificial Intelligence at Certara, is exploring applying generative AI to drug discovery and development to improve efficiency and identify novel therapeutics across various use cases. The focus is on developing specialized secure AI models to integrate internal data with the Certara platform. Generative AI is particularly useful in areas with high specificity, such as antibody design and mRNA therapeutics, where modeling the underlying biology is crucial.  Chris explains, "Certara helps pharmaceutical and biotech companies throughout their process, from early basic research to regulatory filing and beyond. And we're quite a unique company in that we are not developing our own drugs but instead helping companies develop their drugs. And it's something like over 90% of all FDA approvals are projects that, in some way, shape, or form, Certara has helped with." "Our philosophy is to start with the use case. Generative AI is an incredible novel technology. There are many different ways to apply it, but we're interested in how to turbocharge or otherwise ameliorate and create efficiencies in a wide range of the use cases that Certara works on. What we're doing is taking a look at each of those kinds of use cases, trying to identify whether generative AI is useful in those use cases. Then, build out technology-driven solutions that are a combination of gen AI plus services, plus data, plus other software for each of those use cases." #Certara #GenerativeAI #HealthAI #DrugDiscovery #DrugDevelopment certara.com Download the transcript here

    19 min
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4.9
out of 5
16 Ratings

About

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

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