Evidence-Based Health Care

Oxford University
Evidence-Based Health Care

The broad aim of the Centre for Evidence Based Medicine is to develop, teach and promote evidence-based health care and provide support and resources to doctors and health care professionals to help maintain the highest standards of medicine. Many of the talks are taken from the Oxford Evidence-Based Health Care Programme and delivered by members of the Nuffield Department of Primary Care Health Sciences, the Centre of Evidence Medicine and leaders in the field of Evidence-based Health Care internationally.

  1. 12 JUL

    How stories shaped every aspect of our mixed methods study

    Kirsten Prest discusses the 'Encompass' study on care for disabilities in Uganda and its wider application in the NHS, where narrative-driven mixed methods research shaped phases from grants to implementation This talk will explore how a small qualitative study was able to inform a wider body of work, which includes both qualitative and quantitative methods. It will be framed within the “Encompass” study which aims to adapt and pilot test a group programme for parents/carers of children with disabilities originally developed in Uganda, to be implemented in an NHS setting in the UK. The initial qualitative work supported every phase of the mixed methods study from grant applications to key decisions around implementation, to informing the adaptation phase, to considering objectives and outcomes, and finally dissemination and future work. It has provided a wealth of knowledge and rich insights, much of which continues to inform future grant applications. Kirsten is a paediatric occupational therapist and HARP doctoral research fellow. Her clinical and research interests include supporting the wellbeing of families who have children with complex disabilities, improving family-centred services, global child health, global innovation including knowledge transfer from low-resource settings to high-income countries, and research capacity building among allied health professionals. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    36 min
  2. 17 ABR

    Artificial Intelligence and Health Security, managing the risks

    Professor Karl Roberts, University of New England, NSW, Australia gives a talk on generative AI and large language models as applied to healthcare. Dr Karl Roberts is the Head of the School of Health and Professor of Health and Wellbeing at the University of New England, NSW, Australia. Karl has over thirty years-experience working in academia at institutions in Australia, the UK and USA. He has also acted as an advisor for various international bodies and governments on issues related to wellbeing, violence prevention and professional practice. Notably, this has included working with policing agencies, developing policy and practice on suicide, stalking, and homicide prevention. Interpol developing guidance for organisational responses to deliberate events such as biological weapon use. The UK government SAGE advisory group throughout the Covid19 pandemic focusing upon security planning. The European Union advising on biological terrorism, and extremist use of AI. World Health Organisation where he worked in a unit developing policy and practice related to deliberate biological threat events. There has been substantial recent interest in the benefits and risks of artificial intelligence (AI). This has ranged from extolling its virtues as a harmless aid to decision making, as a tool in research, and as a means of improving economic productivity. To those claiming that unchecked AI is a significant threat to human wellbeing and could be an existential threat to humanity. One area of significant recent advancement in AI has been the field of Large Language Models (LLMs). Exemplified by tools such as Chat-GPT, or DALL-E, these so-called generative AI models allow individuals to generate new outputs through interacting with the models using simple natural language inputs. Various versions of LLMs have been applied to healthcare, and have variously been shown to be useful in areas as diverse as case formulation, diagnosis, novel drug discovery, and policy development. However, as with any new technology, there is a potential 'darkside,' and it is possible to utilise these tools for nefarious purposes. This talk will give a brief introduction to generative AI and large language models as applied to healthcare. It will then discuss the potential for misuse of these models, seeking to highlight how they may be misused and how significant a threat they could pose to health security. Finally we will consider strategies for managing the risks set against the possible benefits of generative AI. This talk is based on work carried out by the author and colleagues at the World Health Organisation and the Royal United Services Institute.

    51 min
  3. 12/10/2023

    Evidence-based dentistry: The building of the Dental Fact Box repository – OHA!

    An introduction to OHA!, a tool currently being developed which aims to assist dentists in accessing the most reliable evidence regarding the effectiveness of common dental treatments. The OHA! repository has been purposefully crafted to be exceptionally selective and compact, ensuring that users can easily find straightforward and valuable answers to their dental clinical questions. During the presentation, Professor Paulo Nadanovsky will show two sample dental fact boxes (in draft form) that have been developed. One pertains to the success rate of root canal treatment, while the other focuses on the impact of shorter versus longer intervals between dental check-ups on oral health. Patients expect doctors to take action to help them, and the more treatment or diagnostic tests, the better they feel. Doctors genuinely want to help and can often come up with various treatment or testing options to try. Consequently, this leads to a situation where everyone becomes perpetual patients, regardless of their actual health needs and potential benefits – essentially, an overuse of healthcare. Furthermore, there is a pervasive illusion of certainty among healthcare professionals, including physicians and dentists. This illusion entails the belief that treatments are always effective, diagnostic tests are infallible, and there exists only a single, optimal treatment or management approach. Consequently, there is often a lack of systematic comparisons between the pros and cons of different options. To dispel this illusion of certainty, reduce excessive healthcare practices, and promote clear thinking when considering interventions, the provision of clear information is essential. The practice of evidence-based healthcare involves two distinct roles: that of evidence consumers and evidence producers. Consumers, including clinicians and the general public, often lack the expertise needed to evaluate and choose the most reliable evidence. Hence, it falls upon those producing healthcare evidence to assume the role of experts and develop tools that simplify the integration of the best available evidence into the decision-making process for clinicians and patients alike. Bio: Professor Nadanovsky graduated as a dentist in Rio de Janeiro, Brazil. He worked for a few years in the clinic (mainly periodontics), then migrated to public health and epidemiology and obtained a PhD from the University of London in 1993. He witnessed the birth of the evidence-based medicine movement and of the Cochrane Collaboration while working as a lecturer at the London Hospital Medical College and at University College London (afterwards it was renamed Queen Mary and Westfield College). Professor Nadanovsky taught evidence-based dentistry between 1993 and 1997 and since 1997 has been teaching epidemiology and evidence-based health care to physicians, dentists, nutritionists, and other health care professionals. He supervises PhD and MSc students, and his main interest is in overdiagnosis and overtreatment in health care in general, and more specifically, in dentistry.

    53 min
  4. 23/03/2023

    Evidence in Women's Health: Coil contraceptive - what is it and what are the potential harms for women?

    In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss intrauterine contraception commonly known as the coil. Given the uncertainty around who feels pain, they speak with Dr Neda Taghinejadi, a sexual and reproductive health doctor and academic clinical fellow, who specialises in fitting coils for those who have had problems having them fitted by their GP or who have experienced trauma and require a highly trained specialist. This podcast series on evidence in women's health is brought to you by the Centre for Evidence-Based Medicine and the postgraduate programme in evidence based health care. Dr. Anne-Marie Boylan, a senior researcher and lecturer in the programme, and Associate Professor Jamie Hartmann-Boyce, interview relevant experts discussing the strengths and limitations of different sources of evidence as they relate to women's health and considering their implications for future research. In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr Anne Marie Boylan discuss intrauterine contraception commonly known as the coil. Given the uncertainty around who feels pain, they speak with Dr Neda Taghinejadi, a sexual and reproductive health doctor and academic clinical fellow, who specialises in fitting coils for those who have had problems having them fitted by their GP or who have experienced trauma and require a highly trained specialist. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

    20 min

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The broad aim of the Centre for Evidence Based Medicine is to develop, teach and promote evidence-based health care and provide support and resources to doctors and health care professionals to help maintain the highest standards of medicine. Many of the talks are taken from the Oxford Evidence-Based Health Care Programme and delivered by members of the Nuffield Department of Primary Care Health Sciences, the Centre of Evidence Medicine and leaders in the field of Evidence-based Health Care internationally.

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