Choosing Science: Stories of Perseverance, Humanity, and Success Ana-Maria Zamfirescu
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Finding inspiration and a will to persevere might be challenging at times, especially when you have been prevented by outside forces, in a way or another, to achieve your goals. Although actions speak louder than words, stories of people that succeeded despite opposition can have the power to put wind into someones deflated sails and perhaps also fight against the impostor syndrome so many of us experience . Here I hope you will find such stories, which are mostly focused on scientific figures maybe less popular, but who greatly contributed to the development of science and in the process showed perseverance through obstacles. I will also highlight each individual's humanity, struggles and strength, and break the coldness that I feel exists between science/ scientists and the general public. Be prepared for sarcasm and a bit of fooling around sometimes, because what's life but empty without humour. Enjoy!
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Mice as discovery driver or how to be small, but help achieve great things
Mice (17th century- current)
Some find them cute, some find them repulsive, and science finds them useful. Mice have been a model organism for a bit over a century and is by far the most used nowadays. Let’s find out what these little creatures did for scientific discoveries and learn cool facts about them at the same time.
Resources:
https://www.nature.com/articles/s41593-021-00849-x
https://www.labome.com/method/Laboratory-Mice-and-Rats.html
https://www.sciencedirect.com/science/article/pii/B9780128165737000067
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790571/
Cool facts: https://www.yourgenome.org/facts/why-use-the-mouse-in-research
Video: https://www.nytimes.com/2021/05/25/science/optogenetics-brain-social-behavior.html
Example failed animal trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964774/
Micronucleus test: https://en.wikipedia.org/wiki/Micronucleus_test
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Prof. Rita Levi-Montalcini or how to create a completely new science field in one's bedroom
Professor Rita Levi-Montalcini (1909-2012)
A developmental biologist who left an indelible mark on the field of neuroscience through her groundbreaking discoveries and unwavering dedication to scientific inquiry, despite being forced at one point to conduct her research from the confinements of her bedroom in Turin. From her pioneering research on nerve growth factor (NGF) (which was found to also be involved memory and learning, physical and mental illnesses, and led to antibody based therapies decades after its discovery), to her advocacy for gender equality in academia, Rtia’s contributions continue to inspire generations of scientists worldwide.
References
https://www.pnas.org/doi/10.1073/pnas.1302413110
https://dilemaveche.ro/sectiune/la-fata-timpului/rita-levi-montalcini-o-artista-a-stiintei-2311088.html
“Rita Levi-Montalcini and the discovery of NGf, the first nerve cell growth factor” - Luigi ALOE, Archives Italiennes de Biologie, 149: 175-181, 2011. DOI: 10.4449/aib.v149i2.1377 http://www.architalbiol.org/index.php/aib/article/view/149175/21701989
In praise of imperfection : my life and work. Levi-Montalcini, Rita. 1988
https://www.nobelprize.org/prizes/medicine/1986/levi-montalcini/lecture/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612637/
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Williamina Paton Fleming or how to go from being a maid to changing astronomy forever
Fleming, Williamina Paton (1857–1911)
A single mum, deserted by her husband in a time when women were second class citizens and weren’t allowed to get a higher education, Williamina Paton Fleming rose from the humble position of maid to one of the most famous astronomers in history. She supervised the cataloging of hundreds of thousands of stars, refined the star hunting method and changed the face of astronomy forever. This is the story of an immigrant woman that beat her circumstances and the system by choosing science.
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Prof. Dr. Frits Zernike or how the Nazis did something good by mistake
Frits Zernike
Although he spent his whole life from birth to retirement in the cities of Amsterdam and then Groningen, his life was far from ordinary. Incredibly intelligent and gifted, having the rare combination of simultaneously being a fine theoretician and skilled experimentalist, Frits Zernike started his scientific journey in astronomy and then applied his findings in microscopy. Before his discovery was recognised and awarded a Nobel prize, the Nazis were the first to see the potential in Zernike’s achievement and popularized it, altough it was made public for more than a decade. This is the story of the man that made it possible to see what couldn’t be seen ever before.
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Prof. Dr. Lynn Margulis or how to be so good you get to use swearwords in your scientific titles
Although now Lynn Margulis is as the historian Jan Sapp has said "as synonymous with symbiosis as Charles Darwin's is with evolution", she faced intense criticism in her lifetime. At the beginning her ideas elicited responses such as, "Your research is crap. Don't ever bother to apply again" and has been intitally rejected by 15 journals, in the end her passion and stubbornness prevailed. Strong in her opinions and unbothered by other people's vitriolic attitudes, she was also soft at heart and left a lasting mark on many lives. Lynn lived on one speed only, trailblazing and revolutionizing science and how modern scientist think about the basic biological unit of the eukaryotic cell and its origins. May we all have half of the fate she had in her ideas!
Resources:
https://www.sciencealert.com/10-inspiring-women-in-science
https://www.discovermagazine.com/the-sciences/discover-interview-lynn-margulis-says-shes-not-controversial-shes-right
https://www.youtube.com/watch?v=KlhW12dGfFk
https://www.thoughtco.com/about-lynn-margulis-1224847
https://www.nature.com/articles/480458a
https://www.edge.org/conversation/lynn_margulis-lynn-margulis-1938-2011-gaia-is-a-tough-bitch
Email: choosingscience@gmail.com
Instagram: choosing.science
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Support the Show.
Email: choosingscience@gmail.com
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Dr. Walle Nauta or how to stick it to the Nazis while revolutionising neuroscience
Dr. Walle Nauta was not only a brilliant neuroanatomist and scientist of the 20th century, but also a selfless, brave soul. He revolutionised research tools in neuroscience, making it possible to better understand one of the biggest mysteries of humankind, our brain. Exigent, but kind, intuitive, but rigorous, and most of all, humble, he lived a life to remember.
List of interesting people: John Boren, Joseph
Brady, Boyd Campbell, Sven Ebbesson, Ford Ebner,
Michael Fuortes, Robert Galambos, William Hodos, David
Hubel, Harvey Karten, JacSue Kehoe, John Mason, William
Mehler, James Petras, George Moushegian, Enrique Ramón-
Moliner, Felix Strumwasser, and Eliot Valenstein.
Resources:
Lecture- https://infinite.mit.edu/video/walle-j-h-nauta-gross-anatomy-human-brain%E2%80%9D-brain-dissection-course-mit-department-psychology
https://www.nap.edu/read/11807/chapter/16
http://www.nasonline.org/publications/biographical-memoirs/memoir-pdfs/nauta-walle-j-h.pdf
https://righteous.yadvashem.org/?searchType=righteous_only&language=en&itemId=6748569&ind=NaN
Email: choosingscience@gmail.com
Instagram: choosing.science
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