From PharmD to Pharmacogenomics Test Developer: Dr. Thierry Dervieux’s Story of Revolutionizing Healthcare Through Precision Medicine for Immune Modulated Inflammatory Diseases | PGx For Pharmacists

Becky Winslow, BS, PharmD Host and Pharmacogenomics Medical Science Liaison; Behnaz Sarrami, MS, PharmD, Host and Pharmacogenomics Medical Science Liaison; Thierry Dervieux, PharmD, PhD, Chief Scientific Officer at Prometheus Laboratories


Disclaimer:
Behnaz Disclaimer: These are my personal views and opinions, and I am not speaking on behalf of Castle Biosciences, Inc. Becky Disclaimer: These are my personal views and opinions, and I am not speaking on behalf of any other entity.

Transcription: 

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You're listening to the Pharmacy podcast Network in a world where one size fits all medications dominate the pharmaceutical industry.

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Precision medicine brings a ray of hope for those seeking customized health care.

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Pharmacists have a unique opportunity to help people in need of specialized testing to ensure medications work as intended.

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Welcome to PGX for pharmacists where we unravel the wonders of precision medicine and its potential to revolutionize the way we approach pharmacy care.

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Get ready to uncover the secrets behind pharmacogenomics and how it's transforming lives one genome at a time.

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Hello,

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everyone.

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I'm your host,

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Doctor Becky Winslow.

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And you're listening to the PGX for Pharmacist podcast that we magazine recognized in 2021 as the ninth most listened to genetics podcasts in the world on the PGX for Pharmacist podcast.

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We explore all things pharmacogenomics related and our mission is to educate and advocate for PGX.

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We accomplish this mission through exclusive interviews with highly qualified and well experienced pharmacogenomics.

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Industry leaders such as today's special guest and my name is Baas Sami,

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the co-host of PGX for Pharms podcast,

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Pharmacogenomics,

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medical science liaison and a mentor to pharmacist.

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Connect with us on linkedin and let's get a conversation going.

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We want to hear from you and how you're impacting pharmacogenomic stakeholders and what you have learned throughout your journey.

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Ok.

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So without any further ado,

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I'm extremely pleased to introduce to our audience.

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Doctor Theory Devo,

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the Chief Scientific Officer at Prometheus Laboratories,

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and Perme Prometheus Laboratories is a reference clinical laboratory that's focused on the diagnosis,

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prognosis and monitoring of immune mediated inflammatory diseases.

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So,

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thank you,

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Doctor De for joining us on the podcast.

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Today.

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I'm excited to share your and Prometheus's story with our audience.

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Um in particular,

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I'm excited about you sharing your career journey as a farm D phd and Chief scientific officer and designer of the Predictor PK AD A which is a precision guided dosing test for the optimization of Humira Remicade and their bio cylinders.

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So,

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one of Bana's and my main goals for this episode of the PGX for Pharmacist podcast is to expand our audience's notion of what a PGX test looks like and to inspire them to think bigger than the traditional box PGX test.

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Most of them or most of you are uh familiar with.

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So,

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Doctor D uh I'd like to start the podcast by having our guests um introduce themselves and elaborate on how you are a pharmacogenomics expert.

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Yeah,

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thank you,

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Becky for having me.

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Uh uh Yes.

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So I am a,

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I am a pharmacist uh with uh a family who is a,

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a doctorate in pharmacokinetics.

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Uh I completed my studies in France and I came as a postdoc uh fellow uh to work in the United States about 20 years ago to work on the pharmacogenomic of anti cancer agents,

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uh primarily uh six Maturin as well as methotrexate.

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After my post doc,

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uh I moved uh in industry for promet.

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So I have a large experience in uh uh the implementation of pharmacogenetics testing in immune mediated inflammatory disease.

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Our lab Rome was the first uh clinical laboratory in the United States to offer the fin uh metyl transfer genotyping as well as the thin metabolites.

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So,

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uh uh of uh of 70 publications in the field and uh I'm very uh very excited to have uh to be on the postcard with you uh uh today.

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All right.

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So thank you for qualifying yourself as an expert.

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So,

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let's jump right in and delve into your current PGX work.

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So,

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if you'll tell us um a little about Prometheus,

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specifically,

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what is Prometheus's mission?

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And how are you guys going about accomplishing your mission?

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Yeah,

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sure.

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Uh So Promet is a,

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is a reference uh clinical laboratory based in Southern California in San Diego.

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Uh The company has been there for uh over 25 years.

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We are uh specialize in the differential diagnosis of autoimmune G I disease uh disorders,

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uh gastrointestinal disorder,

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uh and inflammatory bowel disease.

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And over the years,

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we have developed a portfolio of a differentiated solution to facilitate the diagnosis,

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the prognosis,

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the monitoring,

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as well as therapy selection with pharmacogenetics testing,

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which we are offering to our clinical laboratory.

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And most importantly,

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uh recently,

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we are uh uh developing some uh uh testing solution with the credit topic care test to optimize treatment to uh biologics.

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Ok.

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Well,

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that,

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that's great.

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Can you also tell us uh about the Prois Library of Precision Medicine Tests for inflammatory bowel disease for patients?

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how they benefit medication therapy management.

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Stakeholders across the IB DS patients journey from diagnosis to treatment to disease,

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monitoring through remission and how they differ from other lab tests for IBD and his treatments.

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