HardwareX Podcasts

HardwareX

HardwareX provides interviews and deep-dives with scientists and leading experts in open-source hardware. Produced for the journal HardwareX from Elsevier Publishing Company.

  1. 6월 16일

    Open Hardware Talks: Is Open-source 'Disrupting' MedTech? Ft. OpenFlexure, OSI2. and Openinsulin.

    MedTech has an accessibility problem.  Life-saving medicine, groundbreaking diagnostics technologies and much-needed lab equipment at the hands of profit-driven companies and oligopolies. What are the consequences of betting human health on proprietary markets, and what alternatives can open-source offer? In this Open Hardware Talks, Lukas Winter (Open Source Imaging Initiative), Joe Knapper (OpenFlexure) and Anthony Di Franco (OpenInsulin) discuss challenges in healthcare accessibility, the benefits of open source approaches, and the potential future impact on medical technology, with examples from their succesful open-source projects - an OS low-field MRI system, an OS microscope and an OS protocol for insulin. Open Source Imaging Initiative: Access to MRI systems remains highly unequal between regions, countries and the global north-south divide. Millions of people are denied diagnostic healthcare, and crucial research faces constant roadblocks, as scientists struggle to compare results between closed 'black box' systems. OpenFlexure: Optical microscopes are an essential tool for scientific analysis and the detection of diseases in clinics, yet access to high-performance microscopy is limited in much of the world due to high up-front and maintenance costs and brittle supply chains.  OpenInsulin: Most of the world's insulin supply currently relies on the profit-driven business model of three companies. As a result, struggling economies remain undersupplied, and, when a drug is pulled from the market, patients are left shuffling to find alternatives, as seen with the removal of Levemir by Novo Nordisk from the US in 2023.  HardwareX is a peer-reviewed scientific journal about open-source hardware. For more info, visit HardwareX.

    49분
  2. 2024. 12. 09.

    Building A Better Mousetrap: Scaling animal wellbeing with open-source hardware

    What if research labs didn't have to reinvent the wheel all the time? Rodents like mice and rats play a pivotal role in neuroscientific research. Through a process known as 'head fixation', scientists surgically implant cannulas and electrodes to measure neurophysiological activity. As mice share roughly 95% of our DNA, head fixation experiments greatly contribute to advancing our understanding of the human brain and diseases like Alzheimer's and Parkinson's. While head-fixation is common in many labs, proprietary systems are often expensive and inconsistent. This leads many labs to create ad hoc DIY systems at the risk of causing harm to the research animals and impeding the results. In this episode, we sit down with Zack (Isaac) Weaver, PhD, to explore the ethical and design-specific considerations behind his open-source head gear fixation system. With animal well-being in mind, we explore the multi-stakeholder benefits of open-source hardware in research. Open-source hardware is a collaborative effort. A special thanks to co-authors Michael R. Tadross and S. Aryana Yousefzadeh and all the labs and members who contributed to the design by trying and testing various iterations. This episode is researched, produced and edited by Miriam Gradel, Journalist and Media Editor at HardwareX. The music is provided by Kammerin Hunt via Pixabay. HardwareX is a peer-reviewed scientific journal about open-source hardware. For more info, visit HardwareX.

    23분

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HardwareX provides interviews and deep-dives with scientists and leading experts in open-source hardware. Produced for the journal HardwareX from Elsevier Publishing Company.