Genetics in Your World

Genetics Society of America

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The Genetics in Your World podcast spotlights noteworthy studies published in GSA Journals GENETICS and G3: Genes|Genomes|Genetics. Through conversations with the authors, you’ll hear about their research and its significance for the fields of genetics and genomics. The podcast is produced by the GSA Early Career Scientist Multimedia Subcommittee. Hosted on Acast. See acast.com/privacy for more information.

ÉPISODE 1

Breeding Better Berries: Inbreeding and Hybrid Vigor in Strawberries – A Conversation with Dr. Steven J. Knapp

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Faye Romero interviews Dr. Steven J. Knapp of the University of California, Davis about the genetics underlying increased hybrid performance in strawberry cultivars. Read Dr. Knapp’s paper titled, “A dominance hypothesis argument for historical genetic gains and the fixation of heterosis in octoploid strawberry,” published in the December 2024 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/genetics/iyae159. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Thank you to the GSA Early Career Scientist Multimedia Subcommittee, in particular the production team who worked on this episode: Faye Romero, Interviewer and Researcher; Sarah Gilmour, Audio Quality Control Coordinator. Hosted on Acast. See acast.com/privacy for more information.

31 min
ÉPISODE 2

Functions of Blm Helicase N-terminal IDR — A Conversation with Dr. Evan B. Dewey

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Allie Hutchings interviews Dr. Evan Dewey of Winthrop University about the functions of Blm helicase N-terminal IDR. Read Dr. Dewey's paper titled, “Functions of the Bloom syndrome helicase N-terminal intrinsically disordered region,” published in the March 2025 issue of GENETICS: https://doi.org/10.1093/genetics/iyaf005. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Podcast Notes: Bloom syndrome helicase (Blm) has important roles in maintaining genome stability. About half the protein is predicted to be intrinsically disordered (IDR), and its functions are poorly understood. The authors of this study identified regions that are locally conserved in closely related Drosophila species, then deleted these and assayed various functions. They find that each region is required for a subset of Blm functions. The authors’ modeling suggests these regions adopt structure in complex with Top2alpha and the results provide novel insights into Blm IDR functions. Dr. Evan Dewey would like to acknowledge the following colleagues: Colleen C. Bereda, Dr. Jeff Sekelsky, Dr. Christopher A Johnston, Denise Soroka, Dr. Mitch McVey, Carolyn Turcotte, Dr. Nila Pazhayam, Mohamed A. Nasr, Priscila Santa Rosa, Susan McMahan, Dr. Robert J. Duronio, Dr. Gregory Matera, Dr. Dan McKay, and Dr. Richard Cripps. Thank you to the GSA Early Career Scientist Multimedia Subcommittee, in particular the production team who worked on this episode: Allie Hutchings, Interviewer; Sarah Shahba and Laetitia Chauve, Researchers. Hosted on Acast. See acast.com/privacy for more information.

28 min

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The Genetics in Your World podcast spotlights noteworthy studies published in GSA Journals GENETICS and G3: Genes|Genomes|Genetics. Through conversations with the authors, you’ll hear about their research and its significance for the fields of genetics and genomics. The podcast is produced by the GSA Early Career Scientist Multimedia Subcommittee. Hosted on Acast. See acast.com/privacy for more information.

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Genetics Society of America
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16
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2
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Genetics in Your World

Genetics in Your World

Breeding Better Berries: Inbreeding and Hybrid Vigor in Strawberries – A Conversation with Dr. Steven J. Knapp

Functions of Blm Helicase N-terminal IDR — A Conversation with Dr. Evan B. Dewey

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Genetics in Your World

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Breeding Better Berries: Inbreeding and Hybrid Vigor in Strawberries – A Conversation with Dr. Steven J. Knapp

Functions of Blm Helicase N-terminal IDR — A Conversation with Dr. Evan B. Dewey

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Informations