Inquiring Minds

Indre Viskontas
Inquiring Minds

Each week we bring you a new, in-depth exploration of the space where science and society collide. We’re committed to the idea that making an effort to understand the world around you though science and critical thinking can benefit everyone—and lead to better decisions. We want to find out what’s true, what’s left to discover, and why it all matters.

  1. APR 1

    Unlocking the Mysteries of the Social Brain with Dr. Bruce Miller

    In this powerful episode of Inquiring Minds, host Indre Viskontas reconnects with her longtime mentor, Dr. Bruce L. Miller—one of the world’s foremost authorities on dementia, empathy, and the neuroscience of human behavior. Dr. Miller is a Distinguished Professor of Neurology and Psychiatry at the University of California, San Francisco (UCSF), where he founded both the UCSF Memory and Aging Center—the world’s largest research group dedicated to neurodegenerative diseases—and the Global Brain Health Institute, a pioneering global initiative training future leaders in brain health from over 50 countries. As a clinician and researcher, Dr. Miller has spent decades at the forefront of understanding how aging and neurodegenerative conditions alter not only memory, but emotion, identity, and creativity. His forthcoming book, Mysteries of the Social Brain: Understanding Human Behavior Through Science (co-authored with neuroscientist Virginia Sturm), brings together compelling case studies and cutting-edge science to explore how changes in brain function can reveal surprising truths about what makes us human. In their conversation, Indre and Dr. Miller explore: Why do some individuals with dementia develop new depths of empathy or even unlock hidden artistic talents?  How the brain's social networks shape morality, altruism, creativity, and respect—and what happens when these networks deteriorate.  The paradoxes of frontotemporal dementia and how it differs from Alzheimer’s disease in profound and unexpected ways.  How caregiving not only strengthens emotional circuits in the brain but may be one of the most meaningful human endeavors.  Why openness and interpersonal connection are essential to healthy aging and resilient societies.They also discuss the promising future of neurodegenerative disease treatment—from CRISPR-based gene therapies for inherited forms of dementia to new clinical trials exploring the effects of social engagement, exercise, and lifestyle on brain health. With warmth, insight, and deeply human stories, Dr. Miller challenges the traditional view of dementia as a simple unraveling, revealing instead the complexity—and at times, the unexpected beauty—of the aging brain. Mysteries of the Social Brain is available now wherever books are sold.   Resources: Get Dr. Bruce Miller’s new book Mysteries of the Social Brain on Amazon and Routledge Connect with Indre on LinkedIn Inquiring Minds Homepage: https://inquiring.show/ Support the show:  https://www.patreon.com/inquiringminds

    39 min
  2. FEB 4

    Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's with Charles Piller

    In this episode of Inquiring Minds, host Indre Viskontas speaks with investigative journalist Charles Piller about his explosive new book, Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's. Piller unearths the troubling reality behind decades of Alzheimer's research, exposing how fraudulent data, unchecked ambition, and institutional failures have shaped the field—and wasted billions of dollars—while millions of patients and families await real solutions. Piller shares: How a single falsified study published in Nature helped cement the amyloid hypothesis as the dominant theory of Alzheimer’s, despite mounting evidence against it.The role of NIH funding incentives in steering researchers toward confirming flawed findings instead of exploring alternative approaches.The rise of scientific sleuths and whistleblowers like Matthew Schrag, who uncovered image manipulation in key Alzheimer’s studies.The institutional failures of major scientific journals, regulatory agencies, and funding bodies that allowed bad science to shape drug development for decades.Why Alzheimer’s patients and their families are still waiting for effective treatments, and what promising new directions could finally lead to breakthroughs.Despite the troubling revelations, Piller also highlights reasons for optimism, including emerging research into alternative causes of Alzheimer’s, such as viral infections and neuroinflammation, and promising clinical trials involving GLP-1 inhibitors. Listen in for a gripping and eye-opening discussion about how scientific fraud derailed progress in Alzheimer’s research—and how we can chart a new path forward. Doctored is available now at booksellers everywhere. Links: Get Charles Piller’s new book on Amazon: Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Connect with Charles on LinkedIn and X Inquiring Minds Homepage: https://inquiring.show/ Support the show: https://www.patreon.com/inquiringminds

    52 min
  3. JAN 21

    Outraged: Why We Fight About Morality and Politics and How to Find Common Ground with Kurt Gray

    In this episode of Inquiring Minds, host Indre Viskontas speaks with Kurt Gray, a professor of psychology and neuroscience at the University of North Carolina at Chapel Hill and director of the Center for the Science of Moral Understanding.  Gray’s groundbreaking new book, Outraged: Why We Fight About Morality in Politics and How to Find Common Ground, delves into the psychological roots of moral outrage and the societal divisions it fuels. Through scientific insights and engaging anecdotes, Gray explains how our deeply ingrained perceptions of harm shape our moral convictions and why bridging moral divides is both critical and possible. They discuss: The psychological basis of moral outrage and why it’s driven by differing perceptions of harm.How disgust and fear influence our moral judgments and why facts alone rarely resolve disagreements.The role of social media in amplifying moral panics and polarizing society.Why shared stories and genuine listening are more effective than statistics in fostering understanding.Gray also explores myths about morality, including the false belief that humans evolved as apex predators, and provides evidence for how our evolutionary history as prey shaped the cooperative moral frameworks we rely on today. Despite the challenges of polarization, Gray offers hope for bridging divides through empathy, understanding, and open dialogue. Listen in to gain a deeper understanding of how morality drives human behavior, divides societies, and offers pathways for reconciliation.  Outraged is available now at booksellers everywhere. Links: Get Kurt’s new Book “Outrage” on Amazon and visit his website: kurtjgray.com And connect with Kurt on X and Linkedin Inquiring Minds Homepage: https://inquiring.show/ Support the show: https://www.patreon.com/inquiringminds See https://omnystudio.com/policies/listener for privacy information

    48 min
  4. JAN 15

    The Purpose Code: How To Unlock Meaning, Maximize Happiness, and Leave A Lasting Legacy with Jordan Grumet

    In the wake of the devastating fires in Los Angeles where people have lost their homes and all their worldly possessions and when many are questioning their purpose it was a timely moment for host Indre Viskontas to sit with hospice physician, financial independence expert, and author Jordan Grumet to discuss his transformative new book, The Purpose Code: How to Unlock Meaning, Maximize Happiness, and Leave a Lasting Legacy. Drawing from his experience at the bedsides of terminally ill patients and his financial acumen Grumet explores how understanding purpose can help us navigate life’s challenges, overcome loss, and build a meaningful legacy. Grumet shares his insights on: The difference between "big P-purpose," which often leads to anxiety, and "little p-purpose," a path to happiness and fulfillment.How reframing our approach to purpose can help us build lives filled with enriching activities that connect us to others.Strategies for identifying purpose anchors, drawing from childhood joys, regrets, or incremental changes in daily life.The impact of social media on purpose anxiety and how to counter its influence with genuine, personal goals.Jordan’s work weaves together medicine, finance, and the significance of purpose, profoundly impacting those seeking a meaningful life. Listen in for practical advice on aligning your actions with your values, finding joy in small, meaningful pursuits, and creating a legacy that lasts beyond your lifetime.  The Purpose Code is available now at booksellers everywhere. Links: Get Jordan’s new Book at Amazon and visit his website: https://jordangrumet.com/ Inquiring Minds Homepage: https://inquiring.show/ Support the show: https://www.patreon.com/inquiringminds See https://omnystudio.com/policies/listener for privacy information

    42 min
  5. 12/17/2024

    Journey to 2125: One Century, One Family, Rising to Challenges with Gary F. Bengier

    In this episode of Inquiring Minds, host Adam Bristol sits down with Silicon Valley tech expert, philosopher, and acclaimed science fiction author Gary Bengier to discuss his new novel, Journey to 2125: One Century, One Family, Rising to Challenges. As a prequel to his celebrated book Unfettered Journey, this latest work delves into the pivotal technological, political, and societal challenges humanity may face in the next century, all framed through the lens of a multi-generational family saga. Bengier’s unique background—spanning a career as eBay’s Chief Financial Officer to his roles in astrophysics and philosophy—brings an unparalleled depth of realism and foresight to his writing. In Journey to 2125, he explores themes like climate change, robotics, AI, biotechnology, and the shifting labor landscape. The book blends hard science fiction with philosophical reflections, offering both a sobering view of the obstacles ahead and an optimistic call to action for addressing humanity’s most pressing issues. They discuss: The challenges of automation and labor displacement in a rapidly advancing technological landscape.The integration of cutting-edge biotechnology and its societal implications.The global energy crisis and the pivotal role of nuclear fission in the future.The philosophical and economic systems required to navigate an increasingly automated world.Bengier shares insights from his career in Silicon Valley, his work with the Santa Fe Institute, and his early life experiences that shaped his empathetic approach to storytelling. This episode offers a thought-provoking exploration of what it means to thrive in an era of exponential technological change. Listen in to uncover actionable insights and a hopeful vision for building a sustainable and equitable future.  Journey to 2125 is available everywhere books are sold.   Links: Get Gary’s new Book at Amazon   Follow Gary on Facebook @garybengierauthor,  Good Reads @Gary_F_Bengier  and Twitter (X): @GaryFBengier and visit his website: GaryfBengier.com/journey-to-2125/   Inquiring Minds Homepage: https://inquiring.show/ Support the show: https://www.patreon.com/inquiringminds See https://omnystudio.com/policies/listener for privacy information

    57 min
  6. 11/26/2024

    Power Metal: The Race for the Resources That Will Shape the Future with Vince Beiser

    In this episode of Inquiring Minds,  Indre Viskontas sits down with award-winning journalist and author Vince Beiser to delve into the environmental, social, and ethical implications of our growing reliance on electronics and artificial intelligence. Drawing from his new book, Power Metal: The Race for the Resources That Will Shape the Future, Vince sheds light on the often-overlooked competition and global race for the critical metals essential for renewable energy, digital technology, and the foundation of the future. Together, they explore the environmental havoc and political upheaval these resources are already causing—such as unsustainable mining practices and the limitations of recycling—the ways the situation could worsen, the steps we can take to minimize the damage, and the hidden human cost behind the gadgets we use every day. The result is a gripping and sobering account of the battle between what civilization demands and what the planet can withstand. They also discuss: The trade-offs between recycling and reducing consumption.How mining for essential metals like cobalt and lithium impacts the environment and marginalized communities.Promising innovations in resource extraction and sustainable practices.The importance of reducing reliance on cars and investing in bike-friendly, walkable cities.This conversation highlights practical steps individuals and corporations can take to align their values with their actions, from supporting right-to-repair legislation to embracing reuse over constant upgrades. Listen in to uncover actionable insights and hope for building a more sustainable technological future. Links: Read Vince Beiser's book Power Metal: The Race for the Resources That Will Shape the Future Connect with Vince Beiser on LinkedIn: https://www.linkedin.com/in/vince-beiser/ Inquiring Minds Homepage: https://inquiring.show/ Support the show: https://www.patreon.com/inquiringminds See https://omnystudio.com/policies/listener for privacy information

    44 min
4.4
out of 5
825 Ratings

About

Each week we bring you a new, in-depth exploration of the space where science and society collide. We’re committed to the idea that making an effort to understand the world around you though science and critical thinking can benefit everyone—and lead to better decisions. We want to find out what’s true, what’s left to discover, and why it all matters.

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