14 episodes

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

MeSsy with Christina Applegate & Jamie-Lynn Sigler Wishbone Production

    • Society & Culture
    • 4.9 • 2.6K Ratings

On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

    Jennifer Esposito

    Jennifer Esposito

    This week, Christina and Jamie are joined by Jennifer Esposito. Jennifer opens up about her celiac disease and the struggle she went through to get a diagnosis. They also discuss the gaslighting of women, the importance of fighting for your health, her new film "Fresh Kills," and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Vuori- Messy listeners get 20% off your FIRST purchase  at Vuori.com/MESSY and enjoy free shipping on any U.S. orders over $75 and free returns
    Fatty15- Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and use code MESSY at checkout
    BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
    Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. 

    • 1 hr 5 min
    You Get What You Give

    You Get What You Give

    This week, Christina and Jamie discuss feeling trapped, missing high heels, their favorite shows that they’ve worked on, and more.
    This episode was recorded in early 2024.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    AG1 - Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/messy. That’s drinkAG1.com/messy.

    Lume - New customers GET 15% ALL Lume products with code MESSY- and if you combine the 15% off with the already discounted starter pack, that equals over 40% off their Starter Pack! Use code MESSY for 15% off your first purchase at LumeDeodorant.com. 

    BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 53 min
    Katie Couric

    Katie Couric

    This week, Christina and Jamie are joined by Katie Couric. They discuss the importance of community and honesty, why we need more collaboration over competition, the changing media landscape, and more. 
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lolavie -Get 15% off LolaVie with the code MESSY at https://www.lolavie.com/MESSY #lolaviepod 
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 1 hr 12 min
    Jean Smart

    Jean Smart

    This week, Christina and Jamie are joined by Jean Smart. They share memories from when Christina and Jean worked together, and discuss taking back your power, embracing the quiet moments, her career trajectory, and much more.

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This show is sponsored by:
    Maybelline- If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Vuori -Get 20% off your FIRST purchase of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. 

    • 57 min
    Body Talk

    Body Talk

    This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place, and more.
    *Trigger warning: discussion covers eating disorders and body image*

    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.”
    Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com

    • 55 min
    How Did You Know?

    How Did You Know?

    This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions.
    Parts of this episode were recorded in 2023.
    Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
    Audio Engineer: Josh Windisch

    This episode is sponsored by:
    Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more
    Lume: Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code messy at LumeDeodorant.com! #lumepod
    Vuori: For our listeners, they are offering 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY
    BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.

    • 1 hr 5 min

Customer Reviews

4.9 out of 5
2.6K Ratings

2.6K Ratings

Tigers Light ,

So inspired

I love Christina’s self deprecating humor and Jamie’s heart-felt optimism. I am astounded by their raw honesty about chronic pain from MS. And I love their fun little Hollywood tidbits. It was inspiring too to listen to Jennifer Esposito’s story, her film FRESH KILLS sounds incredible and I will definitely go support it while in theaters. Thank you, ladies.

kkluvsrj ,

Thank you ladies 🤗

Thank you thank you thank you so much for using your voices to speak about what you are going through so as normal people do not feel alone. Christina Applegate I’ve always looked up to you and still quote you weekly…look, it’s Jesus! 🥰🤣

Panda_boo 32 ,

Connection

I have just recently been diagnosed with MS at what’s supposed to be the prime of my life. My kids are older in middle and high school and when I turned 40 in January I had dreams for traveling and living life unapologetically… send comes the blindness in one eye or I think I’m having a stroke but after multiple testing and a week stay in the hospital on steroids find out it’s MS thank you for this platform and for sharing everything you share. This is scary and I have so many questions. It’s amazing knowing that I can listen and take comfort from you guys, and this is so much more then you could imagine. Thank you.

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