The SynBioBeta Podcast

John Cumbers

Welcome to The SynBioBeta Podcast: Conversations with synthetic biology’s leading thinkers on building a better world with biology. Hosted by John Cumbers, founder and CEO of SynBioBeta, where tech meets bio and bio meets tech. Stay updated on the latest news in synthetic biology, check out our weekly newsletter and follow us on social media: Twitter | LinkedIn | Facebook

  1. 1 MAI

    From Microbes to Materials—ZymoChem's Vision for a Plastic-Free FutureZymoChem's Vision for a Plastic-Free Future

    In this episode of the Podcast, SynBioBeta founder and CEO, John Cumbers, speaks with Harshal Chokhawala, co-founder and CEO of ZymoChem, about how the company is reengineering the foundations of materials science using microbial fermentation. Harshal discusses his scientific journey from organic chemistry to building a carbon-conserving biotech platform capable of producing bio-based adipic acid, a key component in nylon 66. Their recent partnership with lululemon aims to bring sustainable, high-performance textiles to market. The conversation also touches on ZymoChem’s second major innovation: a biodegradable superabsorbent polymer for use in diapers—a response to the overwhelming waste generated by the hygiene industry. Harshal explains their BAYSE platform, the technology powering these innovations, and how they’re scaling up production to meet market demand. The discussion closes with thoughts on scaling biomanufacturing, policy support, and the broader bioeconomy opportunity in the U.S.

    45 min

  2. 25 AVR.

    Fermenting the Future While Making Biomanufacturing Nimble - with Shannon Hall

    In this episode of the SynBioBeta Podcast, John Cumbers sits down with Shannon Hall, co-founder and CEO of Pow.bio, to talk about how her team is flipping traditional fermentation on its head. Pow.bio’s AI-enabled, continuous fermentation platform decouples cell growth from production—enabling higher yields, faster scale-up, and dramatically lower costs. Shannon shares what led her to leave a successful career at Bio-Rad, why manufacturing is the often-overlooked bottleneck in synthetic biology, and how her company is bringing modern, data-rich, software-driven biomanufacturing to life. From food proteins and fine chemicals to probiotics and enzymes, this episode explores the promise of continuous systems, digital twins, and the smart bioreactors of tomorrow.

    42 min

  3. 16/04/2024

    Scaling New Heights in Biomanufacturing - with Edward Shenderovich

    On this SynBioBeta podcast, John Cumbers talks with Edward Shenderovich, the Founder and CEO of Synonym, a company creating bioeconomy infrastructure to help next-generation bioproducts scale and get to market. Edward will speak at this year’s SynBioBeta conference on “Scaling Biological Capacity,” and in today’s episode, John and Edward will discuss how Synonym addresses some of the challenges in biomanufacturing with its technology-driven products and focus.  Edward Shenderovich is the founder and CEO of Synonym, which provides startups with a way to value the feasibility of their technology and effectively de-risk scalability. Edward has extensive experience in the tech industry and has founded numerous companies and VC firms, including Essential Capital, Knotel, Kite Ventures, and Merchantry. Edward and his co-founder Joshua Lachter started Synonym in January 2022 to establish, fund, and construct large-scale bio-manufacturing facilities, offering synthetic biology producers of various scales adaptable production capabilities while simultaneously providing infrastructure investors with opportunities in a novel, carbon-negative bio-manufacturing asset class. Connect with Edward: @eshender  Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter, and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    58 min

  4. 16/02/2024

    Mycelium Magic: Crafting a Greener Future - with Eben Bayer

    On this SynBioBeta podcast, John Cumbers talks with Eben Bayer, the CEO of Ecovative, a pioneering company at the forefront of developing sustainable materials using mycelium. John and Eben will discuss Ecovative’s journey toward creating a billion pounds of mycelium, explore some of the cutting-edge agricultural technology used in mushroom growing, and discuss the transformative potential of new mycelium crops in consumer goods. Additionally, John and Eben will dive into Ecovative’s unique use of AI and digital twins. Eben Bayer is the CEO of Ecovative, a pioneering company at the forefront of developing sustainable materials using mycelium, Co-founder of My Forest Foods, which uses mycelium to make foods like Mybacon, and is listed as an inventor on 64+ patents. As an entrepreneur, inventor, and futurist, Eben speaks around the world, communicating the immense potential of natural technologies and advocating sustainable stewardship of Spaceship Earth. In addition to his executive roles at Ecovative and MyForest Foods, he advises environmental start-ups in New York and worldwide.  Connect with Eben: @ebenbayer Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    49 min

  5. 05/12/2023

    AI in Action: Synthesizing the Future of Drug Discovery - with Sean McClain

    On this SynBioBeta podcast, John Cumbers talks with Sean McClain, founder, and CEO of Absci, a generative AI drug creation company on a mission to create better drugs for patients faster. Sean and John will continue some of the discussion that we started on the SynBioBeta stage around generative AI and its critical role in drug discovery, some news from AbSci’s recent R&D day, and Sean’s recent visit to Congress to discuss the opportunities and threats from AI and bio. Sean McClain is the Founder and CEO of Absci, which he built from a basement lab to a publicly traded company that continues to strive towards his vision of creating therapeutics at the click of a button. Under his leadership, Absci scaled to over 200 employees, raised over $450M in capital, established a growing number of industry-leading partnerships and built an Integrated Drug Creation Platform that merges bleeding-edge generative AI models with proprietary high-throughput wet-lab data. Sean studied biochemistry and molecular biology at the University of Arizona and has been the recipient of numerous recognitions for his entrepreneurship and innovation. He serves as a board member for the Oregon Translational Research and Development Institute and Life Science Washington. Connect with Sean: @SeanRMcClain Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    54 min

  6. 27/10/2023

    Venture Visions: Investing in the Future of Synthetic Biology - with Ursheet Parikh

    Today, John Cumbers talks with Ursheet Parikh, a general partner at Mayfield Fund, an early-stage, global venture capital firm with a people-first philosophy and a 50-plus-year history of investing and partnering with founders. John and Ursheet will discuss the state of the synthetic biology market and what startups can do to survive and thrive in this turbulent economy. Ursheet Parikh is a general partner at Mayfield Fund, where he has been investing in both human and planetary health companies since 2013. Ursheet’s investments include companies such as Mammoth Biosciences, which has a focus on discovering novel CRISPR systems; Mission Bio, which is looking to apply a Single-Cell Sequencing platform toward oncology; Qventus, which is blazing a trail in Healthcare-AI; and Endpoint Health, which is reshaping the Precision Immunology space—just to name a few. Ursheet holds an MBA from the Wharton School and a Bachelors in Computer Science from the Indian Institute of Technology in Mumbai. He is passionate about accelerating healthcare innovation and transforming college education, where his family foundation is focused. Connect with Ursheet: @ursheet Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    1 h 7 min

  7. 17/05/2023

    Making Data and Computation Accessible to Scientists - with Kyle Giffin

    Today John Cumbers talks with Kyle Giffin, Co-Founder and COO of Latch Bio, the San Francisco-based company that is looking to harmonize data analysis through the application of its integrated bioinformatics platform. Over 50 leading biotechs in drug discovery, therapeutics, agriculture, and climate use LatchBio to accelerate R&D. The team is young, bold, and hiring. To learn more, go to www.latch.bio.  Check out this week’s sponsor: Mayfield Kyle Giffin is a co-founder and the COO of LatchBio. He studied neuroscience and data science at UC Berkeley. In 2021, Giffin dropped out of Berkeley to found LatchBio with the aim of accelerating fundamental science. Connect with Kyle: @kylegiff Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter, and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    44 min

  8. 15/05/2023

    Faster, Better, and Cheaper: The Elusive DNA Triad Now a Reality - with Mike Kamdar & Phil Paik

    In this episode, John Cumbers chats with Michael Kamdar, President & CEO and Phil Paik, CTO, both of whom are  at Molecular Assemblies—a San Diego-based life sciences company developing an enzymatic DNA synthesis technology designed to power the next generation of DNA-based products. The trio will discuss the competitive DNA synthesis landscape, Molecular Assemblies plans for commercialization, and what Mike and Phil envision for the future of the company and the industry. Check out this week’s sponsor: Form Bio Mike Kamdar is an industry veteran with business development and financing expertise who joined Molecular Assemblies in 2016. Mike has been in leadership positions within the biotech industry for numerous years, guiding companies such as Aguron, Pfizer and Hepion, Mike has a bachelor's in biology from St. Joseph’s University and an MBA from Villanova University. Phil Paik has over 16 years of experience in technology innovation and platform development and joined Molecular Assemblies in 2020 after serving as an Associate Director of Engineering at Illumina—where he spent a number of years responsible for fluidics architecture and instrument development. Phil received both his master’s and PhD degrees from Duke University. Connect with Mike & Phil: @molassemblies Connect with John: @johncumbers Stay updated on the latest news in synthetic biology, check out our weekly newsletter, and follow us on social media: Twitter | LinkedIn | Facebook Be sure you make it to our SynBioBeta events! Click here for more information.

    39 min
Tout afficher (27)

Bande-annonce

Notes et avis

4,6
sur 5
11 notes

À propos

Welcome to The SynBioBeta Podcast: Conversations with synthetic biology’s leading thinkers on building a better world with biology. Hosted by John Cumbers, founder and CEO of SynBioBeta, where tech meets bio and bio meets tech. Stay updated on the latest news in synthetic biology, check out our weekly newsletter and follow us on social media: Twitter | LinkedIn | Facebook

Informations

  • Création
    John Cumbers
  • Années d’activité
    2019 - 2025
  • Épisodes
    27
  • Classification
    Tous publics
  • Copyright
    © 2019 SynBioBeta
  • Site web de l’émission
    The SynBioBeta Podcast