MedInsights Unleashed

MedInsights Unleashed
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The MedInsights Unleashed Podcast aims to break down complex clinical data to provide insights from cutting-edge developments into tangible benefits for physicians, patients, and caregivers around the globe. Zee Ramji and John Collins will engage with leading global healthcare specialists to bring the latest groundbreaking therapies to you. To learn more about Zee and John, go deeper into each episode and access additional resources, go to https://medinsightsunleashed.com

  1. 4D AGO

    From Hepatitis to Fatty Liver: Unmasking the New Faces of Liver Cancer

    We’re honored to share a powerful new episode featuring Dr. Pierre Gholam, MD, FAASLD, AGAF—Professor of Medicine at Case Western Reserve University and Director of the Hepatobiliary Multidisciplinary Team at University Hospitals Seidman Cancer Center. With clarity and compassion, Dr. Gholam explores the complex and evolving nature of liver cancer, tracing its historical roots in viral hepatitis to today’s sharp rise in cases driven by fatty liver disease and alcohol use. He highlights both the breakthroughs and ongoing challenges in hepatocellular carcinoma (HCC) care—from early tyrosine kinase inhibitors to the promise of immune checkpoint inhibitors—while underscoring the critical need for improved screening strategies. Throughout the discussion, Dr. Gholam emphasizes the central role hepatologists play in managing HCC, from diagnosis to therapy.

    54 min

  2. AUG 28

    Liquid Biopsies in Neo-Adjuvant Head & Neck Cancer: Personalizing Therapy, Reducing Toxicity

    We are privileged to have Dr. Ari Rosenberg, MD, and Dr. Maha Elsebaie, MD, MSc, from the University of Chicago, join us to discuss groundbreaking research in neoadjuvant head and neck cancer treatment. This episode explores how circulating HPV DNA, measured through a simple blood test, is emerging as a powerful tool to guide therapy decisions, personalize treatment, and potentially reduce the need for aggressive surgery or radiation. The discussion highlights early results from trials combining immunotherapy and chemotherapy before standard treatment, showing promising improvements in tumor response while reducing long-term side effects. This research is shaping the future of HPV-related head and neck cancer care and could change how clinicians plan treatments—bringing us closer to a more precise and less invasive approach.

    47 min

  3. AUG 19

    Melanoma Breakthroughs: Immunotherapy, ROR2, and Ozuriftamab Vedotin

    Groundbreaking research presented at ASCO with Dr. Elinor Barsh, MD, and Dr. Jacob Keeling, MD, focuses on advances in immunotherapy for CTLA-4 resistant melanoma. This episode highlights the importance of recent progress, including the Phase I study of the antibody–drug conjugate ozuriftamab vedotin. Dr. Barsh and Dr. Keeling discuss new clinical trial data, evolving treatment pathways, and the significant reduction in mortality rates achieved with novel therapies. Their collaboration with the Sarah Cannon Research Institute underscores how innovative research can transform patient outcomes making melanoma more manageable despite its aggressive nature.

    54 min

  4. AUG 13

    The CHALLENGE Study: First Phase 3 Proof That Exercise Improves Survival

    Dr. Sharlene Gill, MD, joins the MedInsights Unleashed podcast to discuss the Challenge Study's promising results on exercise in cancer care. Conducted over 17 years, the study revealed that colon cancer patients engaging in structured exercise post-treatment exhibited improved survival rates. The trial involved a comprehensive three-year program incorporating both in-person and virtual components, emphasizing physical activity alongside psychological support. Published in the New England Journal of Medicine (Structured Exercise after Adjuvant Chemotherapy for Colon Cancer) these findings could shift cancer treatment paradigms, advocating for the inclusion of formal exercise programs in post-chemotherapy care to enhance life expectancy and recovery in cancer patients.

    51 min

  5. AUG 7

    Bend the Knee: A Weighted Discussion on Knee Replacement Surgery

    In this episode of MedInsights Unleashed, Dr. Ari Goldman, MD, FAAOS, and Lewis Collins, OPA-C, ATC, OTC, from the Northwell Health Orthopedic Trauma and Surgery Team, uncover the facts on knee replacements. The discussion kicks off with a detailed look at knee anatomy and the factors leading to knee replacements, such as arthritis and genetic predispositions. The episode delves into the importance of maintaining knee health through exercise and weight management. They also explore how alignment issues elsewhere in the body can impact knee integrity and the outcomes of replacement surgery. The episode wraps up with insights into dietary considerations for bone quality and joint health.

    1h 9m

  6. JUL 23

    Quality of Life Over Quantity of Treatment: A Revolution in Neuroendocrine Cancer Care

    Professor Philip A. Philip, MD, PhD, FRCP, Professor of Medical Oncology at Wayne State University School of Medicine and the Henry Ford Cancer Institute, returns to the MedInsights Unleashed podcast discusses the intricate topic of neuroendocrine tumors(NETs), including their rarity, the non-aggressive nature of many cases, and their potential functional characteristics. Prof. Phillip clarifies common misconceptions, advising listeners on the crucial role of accurate diagnosis and the use of grading systems to assess tumor aggressiveness. This episode not only benefits patients seeking understanding of their condition but also serves as a valuable resource for healthcare professionals dealing with these complex cancers.

    56 min

  7. JUL 11

    Breaking the Taboo: Why Early Palliative Care in Pancreatic Cancer Saves Lives and Eases Suffering

    In this episode of MedInsights Unleashed, Dr. Kriti Dhamija, MD, a second-year resident in the Department of Internal Medicine at Allegheny Health Network, Pittsburgh, Pennsylvania, USA, challenges the misconceptions around palliative care, particularly in pancreatic cancer. She explains why palliative care should begin at diagnosis, not at the end of life, and how early referral can reduce ER visits, hospital stays, and ICU admissions. Dr. Dhamija also explores the role of multidisciplinary teams, tackles persistent stigmas, and highlights how even resource-limited settings can improve care using team-based approaches and free guidelines. A must-listen for clinicians, patients, caregivers, and students alike.

    50 min

  8. JUL 2

    C-POST Trial Results: Adjuvant Immunotherapy (Cemiplimab) in Cutaneous SCC with Dr. Danny Rischin, MD

    In a recent episode of MedInsights Unleashed, Dr. Danny Rischin, MD, medical oncologist/clinician researcher at the Peter MacCallum Cancer Centre and Professor, Sir Peter MacCallum Department of Oncology, University of Melbourne, discusses the groundbreaking C-POST study focused on cutaneous squamous cell cancer. By utilizing the immunotherapy drug, cemiplimab, the study achieves a 68% reduction in the risk of recurrence, marking a significant step forward in adjuvant cancer therapy. Dr. Rischin explains the study's meticulous approach to identifying high-risk patients and its impressive 87% disease-free survival rate at two years. He also discusses the role of multidisciplinary care in effectively managing complex cancer cases, emphasizing the need for continued research in uncovering reliable biomarkers.

    33 min
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About

The MedInsights Unleashed Podcast aims to break down complex clinical data to provide insights from cutting-edge developments into tangible benefits for physicians, patients, and caregivers around the globe. Zee Ramji and John Collins will engage with leading global healthcare specialists to bring the latest groundbreaking therapies to you. To learn more about Zee and John, go deeper into each episode and access additional resources, go to https://medinsightsunleashed.com

Information

  • Creator
    MedInsights Unleashed
  • Years Active
    2024 - 2025
  • Episodes
    30
  • Rating
    Clean