Mitochondria Unlocked: Taking Care Of Your Health at a Cellular Level, Rob Fried, CEO @Chromadex

In this episode I sit down with a good friend and mentor Rob Fried, CEO of ChromaDex, who shares his remarkable transition from Hollywood executive producer to leader of a cutting-edge nutraceutical company. Fried's journey from producing films like Rudy and Godzilla to helming a science-focused organization dedicated to extending human healthspan showcases the power of reinvention and following one's passion.

Through ChromaDex's pioneering research into NAD+ and cellular health, Fried has positioned himself at the intersection of scientific innovation and consumer wellness, bringing Hollywood storytelling skills to communicate complex scientific concepts to a broader audience.

The conversation delves deep into the crucial role of NAD+ in cellular health, particularly its impact on mitochondrial function – our cells' power plants. As Fried explains, our NAD+ levels naturally decline with age, accelerated by modern lifestyle factors like poor sleep, excessive alcohol consumption, and environmental stressors. We explore the growing need for consumer education in the supplement industry and draw compelling parallels between the responsible AI movement and the necessity for ethical governance in the supplement space. Fried advocates for establishing a responsible supplement board to ensure product quality, ingredient sourcing transparency, and consumer safety – addressing the current regulatory gaps in the industry.

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About NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) serves as a fundamental molecule in cellular health, playing multiple vital roles throughout the body. At its core, NAD+ is essential for energy production, working within our mitochondria to convert food into usable cellular energy. Beyond energy production, it acts as a crucial coenzyme for hundreds of biological processes, including DNA repair, gene expression regulation, and cellular stress response. NAD+ activates important proteins called sirtuins, which are often referred to as "longevity genes" due to their role in promoting healthy aging and cellular maintenance. As we age, our natural NAD+ levels decline, potentially contributing to various age-related conditions and decreased cellular function. This decline affects multiple aspects of health, including cognitive function, muscle strength, metabolic health, and cardiovascular wellness. Research has shown that maintaining healthy NAD+ levels can support improved energy levels, enhanced cellular repair, better brain function, stronger immune response, and more efficient metabolism. The molecule's influence extends to supporting liver health, promoting muscle recovery after exercise, regulating circadian rhythms, and potentially protecting against various age-related diseases, making it a crucial target for research in healthy aging and longevity science.

About Rob Fried
Robert Fried is the Chief Executive Officer (CEO) of ChromaDex. Mr. Fried is an Academy Award and Emmy Award-winning motion picture producer.  He has held senior roles at entertainment companies Savoy Pictures (CEO), Columbia Pictures (Executive Vice President), and Fried Films (founder, CEO).  He has also founded and served as CEO of internet companies Feeln (now Hallmark Movies Now), WHN (a leading e-commerce service provider), and Healthspan Research (now part of ChromaDex). Mr. Fried holds a B.S. from Cornell University and an M.B.A. from the Columbia University Graduate School of Business.

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