57 episodes

A podcast by University of Michigan neuroscience students that explains how environmental factors like food, pollution, parental care, and drugs can alter the flow of genetic information inside the brain and change our behavior and risk for disease.

Neuroepic: Nature, Nurture, Food, Family, Brains Neuroepic

    • Science
    • 5.0 • 2 Ratings

A podcast by University of Michigan neuroscience students that explains how environmental factors like food, pollution, parental care, and drugs can alter the flow of genetic information inside the brain and change our behavior and risk for disease.

    57. Nutrigenomics of Vitamin B12 and Invasive Cancer

    57. Nutrigenomics of Vitamin B12 and Invasive Cancer

    As a society we are becoming more aware of how daily life patterns directly affect our health and wellness. Exercise, food, and sleep not only influence our short term mental and physical states, but there is increasing evidence that there are lasting effects on our DNA and potentially our offspring’s DNA. Our DNA, or genome, is composed of a specific sequence of nucleotides that control our growth, development, and the ability to carry out biological functions needed for survival. How the DNA is packaged and changes to this packaging is referred to as the epigenome. This can be thought of as a recipe, where the genome is a set of particular directions to make a dish. However, a cook can make a recipe their own and change up the steps to better fit a desired outcome, which is like the epigenome. If more steps are added to a recipe, it becomes more difficult to use, and less people will make the dish, and it can also be simplified by taking out more in depth steps. In the epigenome, changes are made to proteins, making them more or less easily accessible to make genes that our bodies need to function.

    • 9 min
    56. Gestational Diabetes Mellitus

    56. Gestational Diabetes Mellitus

    All a pregnant woman longs for is a healthy, happy baby at the end of her pregnancy. While most women get their wish, the unfortunate reality is that some women have complications for several reasons. One potential complication is Gestational Diabetes Mellitus (GDM), which is when a mother becomes diabetic during her pregnancy. GDM occurs in 12% - 18% of all pregnancies, and the risk of developing this increases with age or a prior diagnosis of diabetes. Women diagnosed with GDM must undergo major diet and lifestyle changes to combat their increase in blood sugar levels. Multiple women discussed how they created restricted meal plans, walked or exercised more, took blood sugar measurements before and after each meal, and sometimes took insulin doses. It is important to educate people about the causes of GDM, as well as the short-term and long-term effects on the DNA of women and their children. Although GDM cannot always be prevented, it is important to understand how women can best help themselves and their children from the lasting effects of GDM.

    • 20 min
    55. Introduction to Nutrigenomics & Nutrigenetics

    55. Introduction to Nutrigenomics & Nutrigenetics

    There is a constant barrage of information about cancer-causing chemicals, damaging pollution, and other toxins making us sick. With headlines like “11 potentially cancer-causing things you might use every day” and news stories about “Environmental pollution killing more people than war”, it’s understandable that the public has become hyper-aware of the health consequences of chemicals and pollution. So, the prospect of protecting yourself and your loved ones with a simple diet change is intriguing.

    • 14 min
    54. Food Shortages: Ukrainians and Americans Need More Than Nutritional Relief

    54. Food Shortages: Ukrainians and Americans Need More Than Nutritional Relief

    The raging conflict in Ukraine is creating a humanitarian crisis through denial of food, water, and housing for those caught in the crossfire. Each day, thousands of people worldwide are added to a growing number of individuals facing food insecurity. Food insecurity is a widespread problem, even during peacetime. Families in the United States cannot afford consistent access to food. We must consider the psychological consequences of food insecurity, in addition to the physiological. The immediate victims are not the only ones affected, and their offspring will suffer from ailments tracing back to starvation.

    • 15 min
    53. Reimagining Epilepsy Care With Food

    53. Reimagining Epilepsy Care With Food

    Epilepsy is a seizure disorder that affects about 3.4 million Americans. It is characterized by abnormal or hyperactive brain cell activity. Although the cause of epilepsy is not always known, certain forms of epilepsy are linked to genetic disorders, stroke, infection, and brain injury. Epilepsy is most commonly treated with medications, which reduce the probability of having a seizure. However, anti-seizure medications don’t work for everyone. Here, we investigate the keto diet and its potential health benefits. We interview patients, families, dietitians, and researchers to uncover the connection between food and epilepsy care.

    • 14 min
    52. Polyphenol Modulation of an Anti-Cancer Response

    52. Polyphenol Modulation of an Anti-Cancer Response

    “Next to water, tea is the most consumed beverage worldwide with approximately 20 billion cups consumed daily,” which is almost 2000 olympic swimming pools. Tea has long been a staple in the diets of individuals all over the world and has been heralded for its health benefits. Lots of people have a cup of tea when they are sick, and recent studies have shown that tea might be able to prevent cancer. Much of the research about the potential anti-cancer effects of tea has focused on chemicals called polyphenols, which are the major active compounds in tea and are also responsible for the distinct flavors and aromas of tea. There are many common dietary sources of polyphenols, including berries, peppers, dark chocolate, red wine, and coffee, and they have a wide variety of health effects. These compounds are structurally diverse, but they all have multiple hexagonal, ring-like components called phenols. Different types of tea can contain different polyphenols. For instance, For instance, the major polyphenol in green tea is a catechin called (−)-epigallocatechin-3-gallate, or EGCG. Theaflavins and thearubigins are commonly found in black tea. Polyphenols are a promising candidate for advancing numerous anti-cancer innovations due to their accessibility through common dietary sources like tea and potential ability to combat cancer through both reversing epigenetic changes and improving the efficacy of cancer treatments.

    • 14 min

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