NEUROSCIENTISTS TALK SHOP Neuroscientists Talk Shop

Jacques Wadiche (UAB School of Medicine) talks to us about multivesicular neurotransmitter release (MVR) in the CNS. He takes us through recent work from his lab that gets at PKA-dependent molecular regulation of MVR whereby synaptic release depends on the number of docked vesicles available for release upstream of release probability.
Duration: 51 minutes
Discussants:(in alphabetical order)
Matt Higgs (Res Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.

Tim Petros (NICHD/NIH) talks about new single cell RNA and epigenetic approaches to understanding the intrinisic programs that determine interneuron diversity. The group discusses how to determine causation vs correlation in identifying candidate mechanisms that regulate interneuron fate decisions, and how historic concepts of cell type (based on morphology, connectivity, physiology etc) map onto transcriptomic data clustering.
Duration: 46 minutes
Discussants:(in alphabetical order)
Annie Lin (Assoc Prof, UTSA)
Asif Maroof (Asst Prof, UTSA)
Salma Quraishi (Res Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.

Steve Small (UT Dallas) discusses how well 19th and 20th century localizationist metaphors for the brain have served our understanding of behavior, especially in the realm of language, and what new strategies are replacing them in the new millennium.
Duration: 46 minutes
Discussants:(in alphabetical order)
Todd Troyer (Assoc Prof, UTSA)
Nicole Wicha (Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.

Matt van der Meer (Dartmouth) talks about the role of oscillations in routing information flow in the ventral striatum.
Duration: 37 minutes
Discussants:(in alphabetical order)
Francesco Savelli (Assistant Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.

Stephen Maren (Texas A&M) talks about the common neural circuitry mediating fear conditioning and drug relapse.
Duration: 39 minutes
Discussants:(in alphabetical order)
Isabel Muzzio (Assoc Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Matt Wanat (Asst Prof, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.

Michelle Diaz (Penn State) discusses how language features might be organized in the neural architecture and her structural and behavioral studies of how language production changes over the lifespan.
Duration: 35minutes
Discussants:(in alphabetical order)
Salma Quraishi (Res Asst Prof, UTSA)
Todd Troyer (Assoc Prof, UTSA)
Nicole Wicha (Professor, UTSA)
Charles Wilson (Ewing Halsell Chair, UTSA)
acknowledgement: JM Tepper for original music.