Professor Sir Andrew Pollard, in conversation with Professor Margaret Stanley OBE, Emeritus Professor of Epithelial Biology at the University of Cambridge. Together they discuss the immune system, the development of an HPV vaccine and the impact of communication on local and global vaccination programmes. Follow us on X @OxfordVacGroup (https://x.com/OxfordVacGroup), and for more information visit the Oxford Vaccine Group website (https://www.ovg.ox.ac.uk). This episode of The Oxford Colloquy was produced and presented by Professor Sir Andrew Pollard and the Department of Paediatrics (https://www.paediatrics.ox.ac.uk), with audio and video production by Greg Jenkins and Karen Carey. The series was edited by Dr. Emma Werner.