Sep 01 2023 This Week in Cardiology This Week in Cardiology

ESC Wrap-up 1: Obesity, heart failure with preserved EF and reduced EF, AF, frailty, evidence translation, and catheter ablation are the topics John Mandrola, MD, discusses in this week’s podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. FRAIL AF
   -FRAIL-AF Study
   https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066485
   -The Most Important Study From ESC: FRAIL-AF
   https://www.medscape.com/viewarticle/996063
II. STEP-HFpEF
Wegovy Scores HFpEF Benefits in People With Obesity
https://www.medscape.com/viewarticle/995844
GLP-1 Agonist Semaglutide in HFpEF Cleared Low Bar
https://www.medscape.com/viewarticle/995872
Semaglutide’s Big Step in HFpEF With Obesity: Investigator Inteview
https://www.medscape.com/viewarticle/995673
   -Semaglutide in Obese Patients With  HFpEF
   https://www.nejm.org/doi/full/10.1056/NEJMoa2306963
III. NOAH AFNET 6
Anticoagulation No Benefit in Presumed AF Detected by Cardiac Devices
https://www.medscape.com/viewarticle/995861
How Much AF Warrants Anticoagulation? NOAH-AFNET 6 Provides Clues
https://www.medscape.com/viewarticle/995871
   -NOAH AFNET-6 – NEJM
   https://www.nejm.org/doi/full/10.1056/NEJMoa2303062
IV. ADVENT
Pulsed Field Ablation Challenges Conventional Devices in AF
https://www.medscape.com/viewarticle/995884
Pulsed Field Ablation Noninferior but Underwhelming in ADVENT
https://www.medscape.com/viewarticle/995898
   -PPFA vs Thermal Ablation for PAF
   https://www.nejm.org/doi/10.1056/NEJMoa2307291
V. BUDAPEST CRT
Impact of RV Pacing in Heart Failure, CRT Benefit Shown in BUDAPEST-CRT
https://www.medscape.com/viewarticle/996035
Supporting Evidence for a Common Practice: BUDAPEST CRT
https://www.medscape.com/viewarticle/995880
   -BUDAPEST CRT Study: European Heart Journal
   https://doi.org/10.1093/eurheartj/ehad591
VI. CASTLE HTx
Advanced HF No Obstacle to AF Ablation Success: CASTLE-HTx
https://www.medscape.com/viewarticle/995897
AF Ablation in End-Stage HF: Is CASTLE-HTx Too Good to Be True?
https://www.medscape.com/viewarticle/995974
   -CASTLE AF (2018)
   https://www.nejm.org/doi/full/10.1056/nejmoa1707855
   -CASTLE HTx
   https://www.nejm.org/doi/full/10.1056/NEJMoa2306037
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