The Clinical Research Podcast

Research & Innovation
The Clinical Research Podcast

Getting to the heart of clinical research through the views of world-leading researchers, scientists and academics involved in answering the big questions about our health. From experimental medicine through to understanding common illnesses like asthma and arthritis, we discuss the latest research, what it means for our health and what scientific discoveries are next. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk.

  1. 2 МАЯ

    Nottingham cancer research is in the top two

    You’d think that clinical researchers would welcome surprises - but they don’t. Even if the results are new and groundbreaking, they want their trials and studies to run in a predictable, controlled way,. And that ability to deliver a total lack of surprise is one of the reasons that cancer research at Nottingham University Hospitals NHS Trust has made it into the top flight in the UK working with major pharmaceutical companies.  As well as clinical and scientific excellence, it’s about building up relationships with our partners so that we know we can deliver on recruiting patients, managing the pharmacy needs, and study set up.  The focus is particularly on chemo-free approach to lymphoma treatment, immunotherapy such as CAR T therapy, bispecific antibodies and using data analysis to target treatments. I talked to Professor Mark Bishton, who’s a consultant haemotologist and the divisional co-lead for research and innovation into cancer and associated. As well as his own research, he’s responsible for delivering the trust’s studies in the specialty. More information at https://www.nuh.nhs.uk/research-in-cancer This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

    15 мин.
  2. 25 АПР.

    Working with Umecrime Cognition on a treatment for Primary Biliary Cholangitis

    Staff at the NIHR Nottingham Clinical Research Facility talk about the UCAB trial. The facility worked with Swedish pharmaceutical Umecrime Cognition to study using a new molecule as a treatment for Primary Biliary Cholangitis (PBC) for patients with severe symptoms of fatigue and cognitive impairment. Quick takeaways -      • one of only two UK locations for first stage drug trial     • kept to tight, complex timelines     • exceeded recruitment targets by building on existing relationships     • patients praised care and treatment The NIHR Nottingham Clinical Research Facility (CRF)  was one of just two centres worldwide – and the only UK facility – to conduct the first part of a clinical study. We were picked because of our expertise in liver disease. We hosted five patients on a purpose-built inpatient ward within the CRF, to confirm the correct dose of the molecule. During their seven-day stay, our team of research nurses and physicians assessed and cared for the patients around the clock. Nottingham CRF has 18 adult and five paediatric inpatient beds dedicated for research, alongside our dedicated outpatient and specialist clinics. In total, there is over 3,400m² of clinical space at our CRF. The PBC study was a randomised, double-blinded and placebo controlled two-part study to evaluate the pharmacokinetics, safety and tolerability, and preliminary efficacy of two dose levels of the new drug. There’s more about it at https://nottinghamcrf.nihr.ac.uk/facilities/case-studies Follow us on Twitter: @NottmBRC Follow us on Instagram: @NottmHealthScience Follow us on Facebook: https://www.facebook.com/ResearchNottingham Watch a video explainer about clinical trials: https://youtu.be/SWS4FCSMWAQ  Read more at https://www.nottinghamresearch.org/get-involved and https://www.nuh.nhs.uk/take-part-in-a-trial and https://www.nuh.nhs.uk/researchvolunteers Email us at  getinvolved@nuh.nhs.uk

    8 мин.

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Getting to the heart of clinical research through the views of world-leading researchers, scientists and academics involved in answering the big questions about our health. From experimental medicine through to understanding common illnesses like asthma and arthritis, we discuss the latest research, what it means for our health and what scientific discoveries are next. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk.

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