Dhru Purohit Show Dhru Purohit

This episode is brought to you by Momentous, Our Place, and Air Doctor. 

We know that the seeds of Alzheimer’s disease are planted at least twenty years before a diagnosis. It’s never too early to think about the lifestyle changes that can influence brain health and reduce the risk of developing neurodegenerative diseases. With all the health and wellness advice out there, it can be challenging to know what to prioritize and what truly matters when it comes to protecting our brain health. Today’s guest breaks it down for us and gives us actionable steps we can implement immediately, regardless of age.

Today on The Dhru Purohit Show, Dhru sits down with neurophysiologist Louisa Nicola. Louisa shares the top three lifestyle factors that can influence our risk for Alzheimer’s disease. She helps us sort through the most current research and uncovers the biggest myths. She also shares the top two supplements that are critical for protecting brain health and the optimal prescription for exercise and resistance training. Looking to protect your brain health? Louisa shows us how.

Louisa Nicola, an Australian-born neurophysiologist and sports scientist, has made significant strides in the field of brain performance and human potential. In 2016, she founded Neuro Athletics, a consulting firm dedicated to optimizing brain health and performance for athletes, executives, and high performers. Louisa's innovative methods improve reaction times, decision-making, and mental acuity. Her vision is to expand Neuro Athletics' reach, empowering more individuals to achieve their full potential through enhanced brain function and mental resilience.

In this episode, Dhru and Louisa dive into (audio version / Apple Subscriber version):

The alarming increase in Alzheimer's disease despite genetics (00:00:36 / 00:00:36)

Why sleep is a critical factor in preventing disease (2:55 / 2:55)

The impact of a sedentary lifestyle on increasing your risk for Alzheimer’s disease and tips for beginners (14:00 / 10:30)

Physiology as we age (28:00 / 24:30)

Fundamental pillars of nutrition and the power of Omega3 fatty acids (36:00 / 31:43)

Creatine for neuroprotection, energy, and reversing osteoporosis (49:00 / 44:14)

The biggest myth about Alzheimer’s disease (56:00 / 51:10)

What motivated Louisa to study Alzheimer’s disease (1:03:00 / 58:02) 

Actionable steps you can implement to reduce your risk (1:07:00 / 1:02:10)

Implementing sauna into your routine to induce good stress (1:10:00 / 1:05:30)

Brain optimization beyond the fundamentals (1:13:00 / 1:08:40)

Social connections that power health (1:21:00 / 1:16:30)

Bigger Muscles-better brain health (1:29:00 / 1:24:30) 


Also mentioned in this episode:

Omega Quant Test

Neuroathletics Instagram

Sleep Regularity as a Predictor of All Cause Mortality Study 


For more on Louisa, follow her on Instagram, Twitter, and YouTube, or visit her website.

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This episode is brought to you by Cozy Earth, Fatty15, and Lifeforce. 

With all the diets out there, determining which one is the right fit is often confusing. Today’s guest offers hope for individuals who may be feeling tired, weak, or dealing with gut challenges and explains why the carnivore diet offers simplicity and reduces inflammation at the root of many of today’s diseases.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Shawn Baker to discuss the carnivore diet. Dr. Baker shares what the diet entails, who can benefit the most from implementing it, and the latest research on what we know and what has yet to be discovered. Dr. Baker also shares his journey to discovering the diet, why many people have seen significant healing and weight loss on the diet and common challenges found within the standard American diet. Dr. Baker gives us insight into the difficulties with the current healthcare system and shows us how personalized medicine is the future of care. 

Dr. Shawn Baker is the Co-Founder of Revero, an orthopedic surgeon, a leading authority on treating disease with medical nutritional therapy, an Amazon best-selling author, world champion athlete, international speaker, podcast host, and consultant. He introduced the zero-carb elimination diet to the world and wrote the best-selling book on Amazon. His personal experience with optimizing health and interacting with thousands of patients has shown powerful results in treating and reversing many chronic diseases.

In this episode, Dhru and Dr. Baker dive into (audio version / Apple Subscriber version):

The carnivore diet on individuals with gut challenges or autoimmune conditions (00:00:04 / 00:00:04)

What does a carnivore diet entail (3:48 / 3:48)

How the carnivore diet heals the gut (11:50 / 8:34)

Who should try the carnivore diet (17:45 / 14:31)

Dr. Baker’s journey that led him to explore the carnivore diet (20:20 / 17:03)

How Dr. Baker implements the diet (34:52 / 30:00)

Weight loss on diet (38:00 / 33:25)

The controversy behind the diet (46:00 / 41:40)

How lowering LDL isn’t the whole story (1:03:00 / 58:00)

Testing to get a fuller picture of heart health (1:07:00 / 1:02:09)

Key biomarkers (1:12:00 / 1:07:10)

Using the ketogenic diet to treat mental health disorders (1:24:00 / 1:19:00)

Prescription medications, research, and bias (1:30:00 / 1:25:30)

Lessons from carnivore diet (1:40:00 / 1:35:00) 


Also mentioned in this episode:


Revero Dr. Baker’s Telehealth company 

Episode with Dr. Michael Twyman and Dhru’s Cleerly results 

Maui Nui protein


For more on Dr. Baker, follow him on Instagram, Twitter, and YouTube, or visit his website. 

Right now, get 30% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.

Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress; go to mylifeforce.com/dhru!
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This episode is brought to you by BiOptimizers, Momentous, and Lifeforce. 

Living a life of longevity includes prioritizing habits that promote health and having the confidence to know what serves your goals and what can sabotage your health. On the road to living to 100 and beyond, today’s guest shares her top tips on longevity, boundaries, and learning to save yourself.  

Today on The Dhru Purohit Show, Dhru sits down with entrepreneur, best-selling author, and host Lisa Bilyeu. Lisa shares the regrets people have when they don’t live life on their own terms and fail to set boundaries that serve their goals. She discusses tuning in to your inner voice and gaining confidence by taking action. Lisa also shares her personal health journey and the daily practices she has implemented to heal her body. Get ready to be inspired by Lisa’s honesty and Radical Confidence.

Lisa Bilyeu is an entrepreneur, producer, best-selling author, public speaker, and host. She co-founded the billion-dollar brand Quest Nutrition and is co-founder and president of Impact Theory Studios, a revolutionary, digital-first studio that produces wildly entertaining and original content focusing on themes of confidence and empowerment. Lisa built a global audience while creating an impressive slate of content, including her hit digital series “Women of Impact,” which features extraordinary guests who, through their stories and expertise, help viewers build their confidence. Lisa tells her story of self-empowerment and success in her best-selling book Radical Confidence.

In this episode, Dhru and Lisa dive into (audio version / Apple Subscriber version):

The biggest regret people have when they don’t live on their terms (00:00:04 / 00:00:04)

Lisa’s top habits that promote longevity and ownership of her health (7:53 / 4:33)

Ideas that can be left behind (17:33 / 14:13)

The top ways that women sabotage their health (34:00 / 29:01)

Using the word “should” to set up false expectations (38:48 / 33:48)

Setting boundaries and being clear on what serves you (42:00 / 37:00)

No one is coming to save you (48:30 / 42:30)

Lisa’s health challenges and what has given her the energy to carry on (54:30 / 49:30)

Our inner voice and the way we speak to ourselves (1:05:00 / 59:50) 

Confidence comes from action (1:17:15 / 1:12:15)

Lisa’s why and her passion to help women (1:22:30 / 1:17:30)

Final thoughts (1:33:30 / 1:28:30)


Also mentioned in this episode:
Lisa's book, Radical Confidence


For more on Lisa, follow her on Instagram, Twitter, Facebook, YouTube, and TikTok, or visit her website, impacttheory.com. 

Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order and free gifts for a limited time.

Optimize your energy and mental clarity with the purest form of creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order. 

Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress; go to mylifeforce.com/dhru! 


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This episode is brought to you by Maui Nui, BON CHARGE, and Aqua Tru. 

Mental health disorders are on the rise at alarming rates. Although access to therapy and medications has increased, the rates continue to grow, leaving millions to suffer. There has to be another approach to treatment, and today’s guest is here to show us what traditional medicine often misses.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Chris Palmer to discuss the rise in mental health disorders and how we need to change our approach to treatment. Dr. Palmer dives into the science behind his Brain Energy theory and shares the research surrounding mitochondrial and mental health. He also sounds the alarm about how alcohol and marijuana use can increase the risk of severe mental health disorders in vulnerable individuals. Dr. Palmer shares inspiring stories of his patients who have overcome mental illness and regained their independence by addressing functional imbalances at their roots.

Dr. Chris Palmer is a psychiatrist and researcher at the metabolism and mental health interface. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of psychiatry at Harvard Medical School. For over 25 years, Dr. Palmer has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has pioneered the use of the medical ketogenic diet in the treatment of psychiatric disorders through research, patient treatment, writing, and speaking around the world on this topic. More broadly, he is interested in the roles of metabolism and metabolic interventions on brain health.

In this episode, Dhru and Dr. Palmer dive into (audio version / Apple Subscriber version):

What's at stake if we don't rethink our approach to mental health? (00:00:51 / 00:00:51)

The impact of alcohol and marijuana on mental health (9:40 / 5:20)

How marijuana impacts brain and mitochondrial function (12:40 / 8:20) 

Using the Brain Energy theory to help individuals who are vulnerable to the effects of marijuana (22:00 / 17:30)

Lifestyle treatment options and the ketogenic diet (27:40 / 23:10)

Optimal exercise and how to start implementing it in your life (39:20 / 34:00)

Ozempic: the impact on mental health and studies on other addictions (48:00 / 42:50)

Ultra-processed foods and the impact on hormones and appetite signals (1:01:00 / 56:20)

The common sense truth behind what we eat affects the brain (1:11:20 / 1:06:10)

Euthanasia in Europe for younger individuals suffering from mental illness (1:21:40 / 1:15:10)

Hope in Dr. Palmer’s work, Brain Energy theory, and final thoughts (1:37:30 / 1:32:00)


Also mentioned in this episode:


Dr. Palmer’s Twitter

Jackson Fyfe, PhD X/Twitter post about weight training reducing all-cause mortality

Study on weight training reducing all-cause mortality


Magic Pill by Johann Hari 


Brain Energy 


For more on Dr. Palmer, follow him on Instagram and Twitter or via his websites, chrispalmermd.com and brainenergy.com. 

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This episode is brought to you by Birch Living, Cozy Earth, and Lumebox. 
The conversation about longevity inevitably includes the goal of aging with strength and vitality. At 70 years old, today’s guest brings a wealth of experience and insight into health and well-being. He discusses his shift from focusing on demanding endurance activities to sustainable activities that bring him joy. Prepare to be inspired.
Today on The Dhru Purohit Show, Dhru interviews Mark Sisson to hear his insights on longevity and wellness. After more than thirty years in the fitness industry, Mark explains why he has shifted his focus away from supplements to prioritize mobility, metabolic flexibility, and intuitive eating. He also tells the story behind his creation of minimalist shoes and discusses the detrimental effects of modern sneakers on our feet. Dhru and Mark explore the lessons from Blue Zones and how we can intentionally integrate them into our lives to create a joyful existence.
Mark Sisson is a prominent health and fitness expert, author, and entrepreneur known for pioneering the "Primal" movement. Transitioning from athlete to advocate, he founded Mark's Daily Apple, a blog promoting ancestral health principles, including a high-fat, low-carb diet, functional fitness, and overall wellness. Sisson has authored several influential books, including The Primal Blueprint. In 2015, he launched Primal Kitchen, a line of health-conscious food products that quickly gained popularity for its clean, real-food ingredients. Sisson's work has inspired millions to rethink conventional health wisdom and adopt a more holistic approach to well-being, emphasizing the importance of natural movement, stress management, and nutrient-dense foods. 

In this episode, Dhru and Mark dive into (audio version / Apple Subscriber version):

Why Mark has doubled down on supplementing with collagen (00:00:32 / 00:00:32)

Why Mark deprioritized supplements in his life (10:50 / 8:08) 

Optimal protein (20:00 / 17:15)

Dhru’s personal journey on prioritizing protein and building muscle (29:30 / 25:00)

Mark’s view on what to eat and develop metabolic flexibility (42:40 / 37:10)

Being flexible and not feeling deprived (45:50 / 41:20)

Eating intuitively (51:20 / 46:45)

Walking and optimal dose (54:30 / 49:00)

Modern shoes and how they harm your feet (1:01:30 / 57:00)

The power of stretching (1:10:45 / 1:06:15)

Lessons from Blue Zones that we can translate into our lives (1:14:30 / 1:10:00)

Being transparent about test results when offering advice (1:20:20 / 1:15:40)

Creating a life of joy (1:33:20 / 1:28:50)


Also mentioned in this episode:

Mark’s Daily Apple

Peluva Shoes 

Study on the impact of bed rest 


For more on Mark, follow him on Instagram, Twitter, or his website. 

To get 20% off your Birch Living mattress plus two free eco-rest pillows, head over to birchliving.com/dhru today.

Right now, get 30% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

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This episode is brought to you by LMNT, Lifeforce, and AquaTru.

Cardiovascular disease is increasingly prevalent among South Asians, particularly Indian immigrants. The rise of this health issue, especially among younger Indian Americans, is attributed not only to lifestyle factors but also to cultural beliefs surrounding success and a lack of emphasis on prioritizing health. Today’s guest joins us in dissecting these nuances and encouraging individuals to focus on longevity.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Manickam Palaniappan (Dr. Pal) to discuss the dangers of belly fat and visceral fat, particularly among the South Asian population. Dr. Pal explains why South Asians should be cautious even if they have a "normal" lipid profile but aren't considered obese by traditional standards. He also shares his personal journey, which led to a deeper understanding of true health and the challenges immigrants face in achieving success. Dr. Pal provides top tips on optimal fiber and protein intake and identifies the risk factors for heart disease.

Dr. Manickam Palaniappan is a renowned gastroenterologist recognized for his expertise in digestive health and innovative treatment approaches. Currently serving as a leading gastroenterologist at a major medical center, Dr. Palaniappan is highly respected for his skill in managing complex gastrointestinal disorders, including inflammatory bowel disease, liver diseases, and colorectal cancer. His commitment to patient care is matched by his involvement in cutting-edge research, contributing to numerous peer-reviewed publications that have advanced the field of gastroenterology.

In this episode, Dhru and Dr. Pal dive into (audio version / Apple Subscriber version):

Why belly fat is dangerous (00:00:02 / 00:00:02)

Dr. Pal’s journey in discovering why visceral fat was dangerous (3:22 / 3:22)

What is visceral fat (12:15 / 8:54)

Genetics versus environment (17: 20 / 14:00) 

The importance of gut health in reclaiming your health (21:20 / 17:00)

The role of excess insulin, flours, and seed oils (28:51 / 24:00)

Risk Factors that impact heart disease (44:50 / 40:00)

Fiber and optimal amounts (49:00 / 44:16)

Prioritizing protein (51:50 / 47:00) 

Body composition test (54:00 / 49:50)

Five points of Gut Man challenge (1:00:00 / 54:30)

Tracking your calorie intake as an assessment tool (1:04:00 / 58:00)

Top mistakes people make in their journey (1:16 50 / 1:12:00)

Final Thoughts (1:22:00 / 1:1:17:00) 


Also mentioned in this episode:
Study on the increase in skeletal muscle index amounts to a reduction in insulin resistance and risk of type 2 diabetes risk

For more on Dr. Pal, follow him on YouTube, Instagram, TikTok, Twitter, or his website. 

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.

Right now, you can save $250 on your first diagnostic and get personalized suggestions. Optimize your longevity and track your progress; go to mylifeforce.com/dhru! 

AquaTru is a countertop reverse osmosis purifier with a four-stage filtration system that removes 15x more contaminants than the bestselling water filters out there. Go to dhrupurohit.com/filter/ and get $100 off when you try AquaTru for yourself.
Learn more about your ad choices. Visit megaphone.fm/adchoices