Eczema Breakthroughs Global Parents for Eczema Research (GPER)

Korey Capozza travels to Spain for the European Academy of Allergy and Clinical Immunology Congress where she speaks to researchers that are trying to explain the allergy epidemic and what we can do about it. Highlights: Dr. Magdalena Zemelka-Wiacek (Poland) explains microplastics cause inflammation. Tami Landau (Israel) uses “big data” to determine which children will develop eczema, and Dr Thomas Bieber (Germany) accesses the German Biobank to understand why some children go into remission.   
Research Mentioned
Mechanisms of gut epithelial barrier impairment caused by food emulsifiers polysorbate 20 and polysorbate 80 
Follow-up to adolescence after early peanut introduction for allergy prevention 
The potential impact of nano-and microplastics on human health: Understanding human health risks
Biomarkers for phenotype-endotype relationship in atopic dermatitis
Development of a predictive model for pediatric atopic dermatitis

Could the diet and lifestyle of a mother during pregnancy influence whether her baby will develop eczema? Our podcast guests are studying the role that diet and the gut microbiome play in pregnancy. Join Dr. Carina Venter and Dr. Susan Lynch as we discuss what pregnant mothers can do to reduce the chances of baby developing eczema or allergies. (And if you like our podcast, consider supporting it with a tax deductible donation).
Research mentioned
Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation
Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy
Different Measures of Diet Diversity During Infancy and the Association with Childhood Food Allergy in a UK Birth Cohort Study  
The Maternal Diet Index and Offspring Microbiota at 1 Month of Life: Insights from the Mediterranean Birth Cohort MAMI 

Frustrated by eczema care that ignores patient priorities? New guidelines from the medical societies for allergists and immunologists may help change that. These guidelines were informed by the views of eczema patients and caregivers and based in evidence (hallelujah!). We chat with the guideline co-authors Dr. Lynda Schneider, founder and director of the Atopic Dermatitis Center at Boston Children’s Hospital, and Dr. Derek Chu, director of  the challenge clinic for allergy diagnosis, research and treatment at McMaster University, about some of the new and surprising ideas they recommend. (And if you like our podcast, consider supporting it with a tax deductible donation). Read the transcript.
Research mentioned
Atopic dermatitis guidelines: 2023 
Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?

Five GPER staff members attended the American Academy of Dermatology conference in February, the biggest gathering of dermatologists worldwide.  We bring you the newest treatments and latest research straight from the source.  Join our conversation with GPER staffers Korey Capozza, Kara Orevillo, Christine Cutaran and Michelle Tu about what stood out this year.  (And if you like our podcast, consider supporting it with a tax deductible donation).

Could we cure allergies by taking probiotics or transplanting the gut microbiome from a healthy person? What does all this mean for eczema/allergy prevention? To find out, join our conversation with Dr. Rima Rachid, allergist and immunologist at Harvard Children’s Hospital, and Meenal Lele, eczema mom and author of Baby and the Biome. We discuss the promising trials with fecal microbiota transplants for food allergic children as well as the best probiotic to take for eczema and when it’s important to take it. (And if you like our podcast, consider supporting it with a tax deductible donation). 
Literature featured in this podcast
The microbial origins of food allergy
Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients 
Lactobacillus rhamnosus Used in the Perinatal Period for the Prevention of Atopic Dermatitis in Infants
The Baby and the Biome book

The winners of the 2023 Big Ideas for Eczema contest share their novel ideas and how they came up with them.  Our citizen scientist winners are Elizabeth Shores, Hannah Mitchell and Armando de la Libertad.  Would you try these ideas?   (If you like our podcast consider supporting it with a tax deductible donation.) 
If you have an idea of your own, find out more about the Big Ideas 2024 competition here.