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MyFSHD Peter L Jones, PhD
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- Wirtschaft
MyFSHD is about education and personal empowerment for the worldwide facioscapulohumeral muscular dystrophy (FSHD) community. Here we have discussions and commentary hosted by FSHD researcher Peter Jones, PhD, on many things of interest to the FSHD community. Learn about the science behind the different FSHD therapeutic approaches, FSHD pathology, family genetics and FSHD diagnostics. We will discuss upcoming clinical trials and what to look forward to. You will get to understand how you can be better prepared, become involved, and help contribute to defeating FSHD once and for all.
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A(+) is still for Avidity: give me the good stuff!
"Whatchyou talkin' 'bout Willis?" In a field where every press release is met with unsubstantiated hoopla and proclamations of BREAKTHROUGH! to fire you up to shake you down, we finally have some real news. We provide our evaluation of Avidity's public interim report on their FORTITUDE AOC-1020 phase 1/2 trial.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message -
Pigs and p38
"You're messing with the wrong guy!!!!" We expand a bit more on the utility of the FSHD-like pig model and then discuss the science behind and implications of p38 inhibition for FSHD.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message -
The three little (FSHD) piggies.
"We don't get a lot of things to really care about." So, you think you are interested in science, eh? Well, let's see how the sausage is made. Today we share our experience generating the FSHD-like minipig models, which will be key tools for testing and advancing better FSHD therapeutics and developing methods for building back your muscles.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message -
CRISPR in the clinic
"Come out to the coast, we'll get together, have a few laughs..." The holiday season we discuss the recent FDA approved CRISPR therapy for sickle cell disease and some dynamics of methylation.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message -
Allow me to reintroduce Jaegerthekidd
"As I leave my competition respirator style, climb the ladder to success escalator style." Today we have the Jaegercast, but first we continue our discussion about apabetalone, a new candidate drug for FSHD.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message -
Assessing the case, so far, for apabetalone as a new drug candidate being investigated for FSHD.
"I don't know how I'm going to live with myself if I don't stay true to what I believe." We evaluate the recent published work describing apabetalone, a small molecule drug from Resverlogix Corp that has been around for awhile and in clinic for other indications and is now being assessed more seriously as a potential therapeutic for FSHD. Overall, while lacking in some areas, this initial study is generally positive and supports that it is a new candidate worthy of further evaluation.
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Send in a voice message: https://podcasters.spotify.com/pod/show/peter-l-jones/message
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