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Welcome to the Foresight Institute’s podcast! Since 1986, Foresight has been advancing technologies for the long-term benefit of life and the biosphere. We focus on three areas: molecular machine nanotechnology for building better things, biotechnology for health extension, and computer science and crypto commerce for intelligent cooperation. This podcast is where we share a portion of our public work fitted for listening. We mix longer discussions with shorter bits, new episodes with all-time favorites. There is much more. To view presentations of our technical work and to stay up-to-date on new content, subscribe to Foresight Institute on YouTube and follow us on Twitter.

The Foresight Institute Podcast Foresight Institute

    • Technologie

Welcome to the Foresight Institute’s podcast! Since 1986, Foresight has been advancing technologies for the long-term benefit of life and the biosphere. We focus on three areas: molecular machine nanotechnology for building better things, biotechnology for health extension, and computer science and crypto commerce for intelligent cooperation. This podcast is where we share a portion of our public work fitted for listening. We mix longer discussions with shorter bits, new episodes with all-time favorites. There is much more. To view presentations of our technical work and to stay up-to-date on new content, subscribe to Foresight Institute on YouTube and follow us on Twitter.

    Longevity + Cryonics + Crypto | Emil Kendziorra, Tyler Golato, Paul Kolhaas, Ole Mensching

    Longevity + Cryonics + Crypto | Emil Kendziorra, Tyler Golato, Paul Kolhaas, Ole Mensching

    Why does signing up to cryonics today make sense? What are people not getting about longevity? And how can the crypto community and the longevity community work together? 
    All of these questions and more are being answered in this episode that was recorded live at the first ever Foresight gathering in Europe, Berlin.
    The panel consists of: 
    Dr. Ole Mensching, Apollo VC
    Tyler Golato, VitaDAO
    Paul Kolhaas, VitaDAO
    Emil Kendziorra, Tomorrow Biostasis
    Announcement:
    2022 Foresight Fellowship Applications in Biotech & Health Extension, Molecular Machines, Computer Science & Cryptocommerce are open! Learn more, apply to become a Fellow, or share the app with others who could benefit from it: https://foresight.org/2022-foresight-fellowship-application/
     
    Applications will be open until October 1st  2021.


    Music: 
    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 
    Danse Morialta by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1200026
    Artist: http://incompetech.com/

    • 36 Min.
    Anders Sandberg | Post-Scarcity Civilizations & Cognitive Enhancement

    Anders Sandberg | Post-Scarcity Civilizations & Cognitive Enhancement

    “If we get to a post-scarcity society, with much greater levels of well being and really long lives, settling space, etc., that means we have a lot to look forward to when it comes to the future!”
    What is available in the “nearer-term” for life if our immature civilization can make it past the current and upcoming tech/insight/coordination hurdles? In this episode we speak to Anders Sandberg on post-scarcity civilizations, to get a sense of what is possible just past current human horizons in the hope it may inspire us to solve humanity’s current challenges and to unlock this next level.
    Anders Sandberg is a Foresight Senior Fellow and a Research Associate at the Future of Humanity Institute from the University of Oxford. Sandberg’s research at FHI centers on management of low-probability high-impact risks, estimating the capabilities of future technologies, and very long-range futures. Topics of particular interest include global catastrophic risk, cognitive biases, cognitive enhancement, collective intelligence, neuroethics, and public policy.
    If you enjoy what we do please support us via Patreon: https://www.patreon.com/foresightinstitute. 
    If you are interested in joining these meetings consider donating through our donation page: https://foresight.org/donate/   
    Music: 
    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 
    Danse Morialta by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1200026
    Artist: http://incompetech.com/

    • 1 Std. 24 Min.
    David Baker | De Novo Protein Design

    David Baker | De Novo Protein Design

    “We use this sort of de novo protein design, to design brand new proteins that block viruses such as the Coronavirus from entering cells.”
    How can new progress in nanotech help us fight the coronavirus?
    In this episode David Baker from the University of Washington presents breakthrough advancements in de novo protein design. Results are easily transferable to the production scale on a rapid timeline of weeks. Applications of this new technology are vast in breadth and depth. Present interests are designing protein assemblies for molecular machines. Another application is targeting cells with a more accurate computational recognition method. A third application is clinical trials that are underway of a novel vaccine that is highly effective against coronavirus. 
    You can find a full summary of this talk here (including video): https://foresight.org/salon/protein-based-assemblies-and-molecular-machines-david-baker-university-of-washington/ 
    If you enjoy what we do please support us via Patreon: https://www.patreon.com/foresightinstitute. 
    If you are interested in joining these meetings consider donating through our donation page: https://foresight.org/donate/   


    Music: 
    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 

    • 40 Min.
    Alex Zhavoronkov | Longevity as a Service

    Alex Zhavoronkov | Longevity as a Service

    “Humans are the only species that understand that they are aging and dying. So we try to avoid thinking about aging and we are now starting to think about prevention.”
    In this episode, Alex Zhavoronkov, CEO and Founder of Insilico Medicine and Deep Longevity, offers his roadmap for what he calls Longevity as a Service. He explains the approach Deep Longevity and Young.ai are taking, the various clocks and machine learning methods they are using, the necessity for physician education and coordinated building of a longevity ecosystem spanning physicians, clinics, insurers, academia, pharma, and more. He also goes into detail about a promising new interesting field of longevity psychology and connected subjective and psychological clocks.
    More resources on this talk (including slides, video, notes) can be found here: https://foresight.org/salon/longevity-as-a-service-ai-aging-clocks-alex-zhavoronkov-deep-longevity-insilico-medicine/
    The original audio recording has been altered for the purpose of this podcast.
    Music:
    Is That You or Are You You by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://chriszabriskie.com/reappear/
    Artist: http://chriszabriskie.com/


    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 

    • 1 Std. 11 Min.
    Nir Barzilai | Targeting Aging with Metformin

    Nir Barzilai | Targeting Aging with Metformin

    “We are here representing the field of the science of aging. And we think that this is a historical day for us, because we're going to offer something that will be paradigm changing.”
    Nir Barzilai, professor at Albert Einstein School of Medicine and director of Institute for Aging Research, presents the current state of the groundbreaking TAME trial serving as a framework and data springboard for the whole longevity field, as well as the future plans for other TAME-like trials with other drugs with high potential for repurposing for aging. At the end he also answers questions about the trial itself and why it is designed the way it is, but also some frequently asked questions about Metformin, like its effect on muscle building with exercise, the ideal dosing, and others.
    The original audio recording has been altered for the purpose of this podcast.

    Music:
    Candlepower by Chris Zabriskie is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://chriszabriskie.com/divider/
    Artist: http://chriszabriskie.com/
    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 

    • 52 Min.
    Morgan Levine & Jamie Justice | On Biomarker Standardization

    Morgan Levine & Jamie Justice | On Biomarker Standardization

    “For me being able to quantify aging is one of the most important endeavours in the field. There is a lot of emphasis on intervening in aging, to either reverse or slow it, but I would argue that there’s no way to test if you did that, if you can’t directly measure the thing that you’re trying to intervene in.”
    In this episode, Morgan Levine, Assistant Professor at Yale, gives a sneak peek into the new epigenetic clock they are developing that is able to probe into multiple organ systems, as well as on a new approach on how to calculate clocks that is much more reliable, enabling to generate insights from methylation clocks with much smaller samples required.

    The second talk is given by Jamie Justice, Assistant Professor at Wake Forest, and covered the current ways and strides the longevity field is making towards validating biomarkers of aging through clinical trials, shown on examples of a few senolytic trials they made. She also explains how exactly the TAME trial, which she is a coordinator of, should serve as a vehicle for the field to move further and have a flagship trial to validate new aging biomarkers against in the future.
    Music:
    Fast Talkin by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100590
    Artist: http://incompetech.com/
    I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/
    Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199
    Artist: http://incompetech.com/
    Remarks: The length of this recording has been altered. 

    • 43 Min.

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