The Joe Cohen Show SelfDecode

Join Joe as he delves into his journey with MSM (Methyl Sulfonyl Methane) supplementation, a key to detoxing the body and enhancing recovery. 

In this episode, Joe discusses:


The Impact of Heavy Metals on Health: Understanding the dangers of heavy metals and the importance of detoxing them from our bodies.


MSM as a Detox & Methylation Aid: How MSM supplementation helps clear heavy metals and play a vital role in methylation.


Recovery and Resilience Through MSM: How MSM aids in the recovery of tendon and joint injuries, contributing to better exercise outcomes.


Combining Sulfur Sources for Optimal Detox: Strategies in integrating MSM with other sulfur sources.


Enhanced Health Markers: Insights into how MSM positively influences key health markers like homocysteine, DHEA sulfate, ALT, and HSCRP.



Discover the powerful role of MSM in detoxing heavy metals and enhancing physical recovery. 

Tune in to learn how this supplement could revolutionize your approach to health and detoxification.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

Buy Jo’s Resistant Starch on Amazon

Join Joe as he explores the powerful benefits of resistant starch as a natural alternative to Ozempic. 

In this episode, Joe dives into how resistant starch not only supports weight management and cognitive function but also promotes gut health—all without the side effects associated with pharmaceutical options like Ozempic.

Joe discusses:


Resistant Starch for Health: How this natural supplement enhances the production of butyrate, GLP-1, and how these play significant roles in weight loss, muscle growth, and overall health improvement.


Cognitive and Mood Enhancement: Insights into how increasing BDNF levels through butyrate production can boost cognitive functions and mood.


Comparison with Ozempic: Joe compares the effects and side effects of resistant starch with Ozempic, providing a detailed analysis based on his personal experiences and scientific research.


Practical Advice on Dosage: Detailing the specific dosage of resistant starch used in a recent study published in Nature in 2024, which demonstrated substantial benefits in weight management.



Tune in to learn why resistant starch might be the key to achieving your health goals naturally, making it a foundational supplement for enhancing immune function, preventing chronic diseases, and improving cognitive health.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, Joe has an in-depth conversation with Dr. Rita Marie, a licensed doctor of chiropractic and the founder of the Institute of Nutritional Endocrinology, about the importance of personalized healthcare in addressing insulin, thyroid, adrenal, and digestive imbalances through the integration of genetics and lifestyle changes. 

Dr. Rita Marie discusses her approach to helping patients by not only looking at conventional lab tests but also incorporating genetics and lifestyle factors such as diet, sleep, and stress management to create a comprehensive health strategy. 

She emphasizes the necessity of moving beyond one-size-fits-all solutions to tackle health challenges, the motivational power of understanding one's genetic predispositions, and the significance of practitioners being curious and knowledgeable about nutritional biochemistry and genetics. 

Additionally, the conversation delves into the necessity of optimizing health before issues become irreversible and highlights some of the common markers and supplements considered in Dr. Rita Marie's practice.

- If you’re a health practitioner, visit inemethod.com

- Visit https://drritamarie.com/

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/

In this episode, Joe dives deep into the effects of megadosing AKG (Alpha Ketoglutarate), a crucial supplement in metabolic pathways and its implications for longevity. Discover the risks and rewards as Joe recounts increasing his AKG intake to 15 times the standard dosage, leading to notable side effects such as enhanced anxiety and sleep issues. 

Joe meticulously explains the biochemical transformation of AKG into glutamate and reviews strategies to counteract these negative impacts, including the use of supplements like B6 and Niacin. 

He concludes by weighing the pros and cons of AKG.

Tune in to learn more about AKG supplementation, its potential benefits, and how to safely navigate its use for optimal health outcomes

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process. 

We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine. 

Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particularly in the reaction facilitated by the BHMT enzyme, making it crucial for reducing homocysteine levels and supporting cardiovascular and neurological health.

We also explore the complexity of methylation pathways and emphasize the need for a comprehensive evaluation of multiple genes to truly understand and optimize methylation.

Be sure to follow our podcast for more expert insights into how betaine, methylation, and genetics can be leveraged to optimize both body and brain health.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease. 

Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and increased energy levels.

Joe draws on personal experiences to compare the negatives against the significant positives of niacin, as he explores niacin's biochemical effects, particularly its interaction with proteins such as 2PY, 4PY, and VCAM1, all linked to cardiovascular health. 

Throughout the episode, Joe examines the importance of dosage, sharing insights into the varying effects of low versus high doses of niacin. 

Join Joe as he navigates the complexities of niacin use, advocating for a well-informed, nuanced approach to its benefits and risks.

If you're interested in learning more about how your DNA and genetics affect your health:

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/