Extend Podcast with Darshan Shah, MD

Darshan Shah, MD
Extend Podcast with Darshan Shah, MD

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.

  1. 5 DAYS AGO

    27. Dr. Mindy Pelz: The Metabolic Reset Every Woman Needs

    Title: Dr. Mindy Pelz: The Metabolic Reset Every Woman Needs Your hormones deserve better care—and you do too. So many women feel stuck when it comes to their health—frustrated by unexplained weight gain, unpredictable mood swings, and low energy that no diet or workout seems to fix. The truth is, our healthcare system was built around research that overlooked the female body’s complexity. But the great news? There’s a way to support your body that works with your biology, not against it. In today’s episode of Extend, I’m diving into how you can break free from metabolic imbalances and reclaim your energy with the right strategies for fasting, nutrition, and movement. You’ll learn why women experience hormonal chaos during perimenopause and menopause—and how understanding your body’s natural rhythm can make all the difference. I’ll also uncover the truth about hidden disruptors in your food and environment, like obesogens and toxins, and how they affect your ability to lose weight and stay healthy. Plus, I’ll share game-changing insights on building strength, improving bone health, and balancing your hormones through strategic lifestyle changes. Joining me is Dr. Mindy Pelz, a pioneer in women’s health and the bestselling author of Eat Like a Girl. Dr. Mindy’s groundbreaking work has empowered thousands of women to embrace fasting, rethink their nutrition, and overcome hormonal imbalances. As the host of The Resetter Podcast, she’s built a global community dedicated to helping women live vibrant, resilient lives. This conversation will open your eyes to what’s possible when you tune into your body’s innate intelligence—you won’t want to miss it! We Also Discuss: (00:00) Women's Health Disparities in Medicine (14:06) Medical Paradigm Shift Towards Individualized Care (21:28) Exploring Fasting and Metabolic Health (33:00) The Truth About Obesogens and Toxins (45:00) The Power of Strength Training and Movement (01:12:00) Reclaiming Balance: Key Lifestyle Shifts for Hormonal Health   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Mindy Pelz   Website: https://drmindypelz.com/ Instagram: https://www.instagram.com/dr.mindypelz

    1h 34m
  2. 24 JAN

    26. Speed Up Your Metabolism NOW (The Power is in Your Muscles)

    In today’s episode of Extend, I’m diving into one of the most powerful and underutilized tools for your health and longevity: strength training. Whether you’re a gym regular or just getting started, this episode will break down the science and practical strategies you need to transform your fitness routine. Together, we’ll explore the four essential pillars of strength training: building and preserving muscle as you age, how your muscles directly impact your metabolism, the surprising role of muscles as an endocrine organ, and how to create an effective, sustainable routine that fits your lifestyle. From understanding the difference between slow and fast-twitch muscle fibers to how myokines impact everything from brain health to inflammation, this episode is packed with game-changing insights. I’m also sharing actionable tips for optimizing your workouts, from training to failure for muscle growth to recovery techniques like proper sleep, protein intake, and using saunas post-workout. Whether you’re 20 or 70, it’s never too late to reap the life-extending benefits of strength training. Ready to take your fitness to the next level? Tune in ! I also discuss: (00:12) Why Strength Training is the Ultimate Longevity Tool (03:14) The Truth About Muscle Loss and Aging (06:35) How Strength Training Transforms Metabolic Health (17:38) Strength Training: The Key to Consistency and Longevity   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/

    17 min
  3. 21 JAN

    25. Mona Sharma: The Shocking Role Your Gut Plays in Cravings and Fatigue

    Feeling stuck with your health? Maybe you're doing all the right things—or at least you think you are—but you're still not seeing the results you want. It’s frustrating, right? But here’s the thing: modern life is working against you. Chronic stress, hidden toxins in your environment, and mixed messages about what actually works—it’s no wonder so many of us feel lost when it comes to wellness. In today’s episode of Extend with Dr. Shah, I’m sitting down with Mona Sharma—nutritionist, wellness expert, and someone who truly gets what it takes to turn things around. We’re diving into the real reasons you might not be feeling your best, from the role of your gut health to how stress affects your body more than you realize. We also share simple, actionable ways to detox your life—without feeling overwhelmed—and how to build daily habits that stick, so you can finally feel like the best version of yourself. Mona Sharma is a leading voice in the wellness space, blending her background in integrative nutrition with her expertise in mindfulness and Ayurveda. Mona’s worked with top athletes, A-list celebrities, and people just like you to rebuild their health from the inside out. If you’re ready to break free from the cycle of exhaustion, stress, and frustration, you’re going to love this conversation. Let's jump in!    We Also Discuss: (00:00) Podcast Launch Strategy and Personal Journey (08:43) Exploring Health, Vibrational Shifts (17:19) Navigating Wellness (28:02) Optimizing Digestion and Reducing Toxins (39:52) Detoxifying Your Environment for Health (52:35) Embracing Emotional Health and Wellness (55:53) Creating Daily Rituals for Optimal Health (01:29:24) Foundations of Everyday Health Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/   Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Mona Sharma: Website: www.monasharma.com Instagram: @monasharma

    1h 34m
  4. 14 JAN

    23. Louisa Nicola: The Simple Habits That Will Rejuvenate Your Brain

    Your brain is your most powerful asset—so why do so many of us let it decline without a fight? Cognitive decline, brain fog, and even Alzheimer’s don’t just “happen.” They’re the result of decades of small decisions, stress, and overlooked habits. The good news? You have the ability to take control. In this episode of Extend, I sit down with Louisa Nicola, neurophysiologist and human performance coach, to uncover the science behind optimal brain health and the simple habits that can keep your mind sharp and resilient.  We talk about the role of exercise (and why your muscles are key to brain health), how sleep works like a "cleaning system" for your brain, and why inflammation is the root of so many cognitive issues. Louisa Nicola is a neurophysiologist and founder of NeuroAthletics, specializing in brain optimization and cognitive performance. With a background as an elite triathlete, she focuses on using exercise and science-backed protocols to prevent neurodegenerative diseases. Louisa works with top executives, athletes, and high achievers worldwide. We Also Discuss: (00:00) Neurophysiology and the Foundations of Brain Health (22:11) The Role of Nutrition in Brain Optimization (34:05) How Aerobic and Resistance Training Transform Brain Function (50:01) Deep Sleep: The Brain's Most Powerful Recovery Tool (56:59) Understanding Alzheimer’s Disease and How to Prevent It Resources mentioned: The Levine Protocol Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Louisa Nicola: Website: https://www.neuroathletics.com.au/  Instagram: https://www.instagram.com/louisanicola_

    1h 31m
  5. 7 JAN

    21. Dr. Jay Shah: The Deadly Effects of Hypertension You’re Not Aware Of

    Do you know the #1 preventable cause of death worldwide? It’s high blood pressure—a condition that half of the population doesn’t even know they have. Mismanaged and misunderstood, this "silent killer" leads to heart attacks, strokes, kidney failure, and dementia. Yet, most people rely on outdated tools like cuffs that deliver inconsistent readings or aren’t used correctly at all. In this episode of Extend, I sit down with Dr. Jay Shah, a cardiologist and blood pressure expert to tackle the barriers holding us back from controlling hypertension effectively. Together, we explore how innovative tools are not just changing how we measure blood pressure, but how we approach prevention, treatment, and even early detection. We also talk about topics like metabolic syndrome, the connection between stress and hypertension, and how small lifestyle changes can yield big results.  Dr. Jay Shah is a practicing cardiologist with over 15 years of experience, including tenure at the Mayo Clinic and Mass General. Now the Chief Medical Officer at Aktiia, he is leading the charge in developing wearable health technologies that aim to transform global blood pressure management. We Also Discuss: (00:00) Health Presentation at Harvard Business School (18:14) Understanding Metabolic Syndrome and Its Connection to Blood Pressure (32:52) Lifestyle Factors and Their Impact on Hypertension (40:40) Stress, Sleep, and Their Role in Blood Pressure Management (48:51) Identification and Management of Resistant Hypertension (01:00:15) Strategic Use of Blood Pressure Medications (01:06:16) The Evolution of Continuous Blood Pressure Monitoring Technology (01:12:28) Future Innovations in Blood Pressure Monitoring and Predictive Health   Thank You to Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/  IFIT: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Jay Shah:   Website: https://aktiia.com Instagram: https://www.instagram.com/aktiiaglobal/

    1h 30m
  6. 31/12/2024

    20. Dr. Rangan Chatterjee: Burnout Is Rewiring Your Brain—Here’s How to Take Back Control

    Are you stuck in a relentless cycle of stress that’s draining your energy and joy? Burnout isn’t just about feeling tired—it’s a chronic state that rewires your body and mind, often without you realizing it. In this episode of Extend, I sit down with Dr. Rangan Chatterjee, a trailblazer in functional medicine and best-selling author, to explore how modern life has hijacked our stress response systems. Together, we unpack why today’s constant pressures—from overflowing inboxes to endless social media scrolling—are leaving so many of us overwhelmed and disconnected from our true selves. We dive into Dr. Chatterjee powerful strategies for addressing burnout, including the surprising benefits of micro-habits like a 5-minute workout or a tea ritual. We also discuss the profound impact of aligning your daily actions with your core values and how these practices can transform your well-being. Dr. Rangan Chatterjee is a globally recognized pioneer in functional medicine, the author of six best-selling books, including Make Change Last, and the host of the widely celebrated Feel Better, Live More podcast, which has over 250 million downloads. With over two decades of clinical experience, he has empowered millions to take control of their health through practical, sustainable lifestyle changes.   We Also Discuss: (00:02) Functional Medicine Foundations (11:55) Understanding and Combating Burnout (23:11) Creating Sustainable Health Routines (50:37) The Power of Intentional Living (01:47:14) Personalized Health and Data (01:06:46) Transforming Health Through Self-Discovery (02:25:37) Rethinking Healthcare and Advocacy (02:33:23) Revolutionizing Health With Functional Medicine   Thank You to Our Sponsors: Timeline: If you are looking for a boost in a cellular level, Timeline is the secret to unlocking your mitochondria's whole potential. Go to: https://www.timeline.com/ TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/   Learn more about Dr. Rangan Chatterjee: Website: https://drchatterjee.com/ Instagram: https://www.instagram.com/drchatterjee

    2h 35m

About

Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results. That's why this podcast is all about cutting through the noise on how to turn back the aging clock. I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health. Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.

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