How to Hack Your Stress and Engineer Your Tears to BOOST Longevity | Jeff Krasno

The Human Upgrade with Dave Asprey

What if the key to living longer isn’t avoiding stress—but mastering it 

Jeff Krasno, founder of Commune and renowned stress expert, joins Dave to reveal why most of us have stress all wrong. In this fascinating conversation, Jeff redefines how we think about stress—showing how it can be your greatest ally instead of your worst enemy. From his groundbreaking new book Good Stress to the ancient practices that have stood the test of time, Jeff shares how to unlock the hidden potential of stress to build resilience, foster connections, and boost longevity. 

You’ll discover why crying is an emotional biohack, how to spot the fine line between good and bad stress, and why the modern world keeps us stuck in a chronic stress loop—and how to break free. Jeff also dives into the science of emotional regulation, the role of connection in health, and the radical power of embracing discomfort to create balance and ease in your life. 

What You’ll Learn: 

• How to turn stress into a tool for resilience and longevity 

• Why Jeff calls chronic ease the root of modern disease 

• The science of tears: how crying regulates stress and boosts health 

• How you can build a “psychological immune system” for emotional regulation 

• The key to balancing good stress and avoiding burnout 

• Why discomfort is the path to growth—and how to embrace it 

Resources:  

2025 Biohacking Conference: https://biohackingconference.com/2025 

Jeff Krasno’s Website – https://www.jeffkrasno.com/ 

Preorder Good Stress – https://www.onecommune.com/goodstressbook#preorder 

Follow Jeff on Instagram – https://www.instagram.com/jeffkrasno 

Danger Coffee: https://dangercoffee.com 

Dave Asprey’s Website: https://daveasprey.com 

Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books 

Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

Own an Upgrade Labs: https://ownanupgradelabs.com 

Upgrade Labs: https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 

SPONSORS:  

  • Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. 
  • Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 

Timestamps: 

• 00:00 – Intro 

• 01:02 – Meet Jeff Krasno 

• 02:16 – Topanga Fires Survival 

• 04:14 – Good Stress vs. Bad Stress 

• 06:14 – Cortisol’s Role in Stress 

• 13:13 – Social Media Triggers 

• 20:32 – Stressful Conversations 

• 31:34 – Cold Therapy Benefits 

• 42:26 – Stress and Recovery Balance 

• 45:58 – High Altitude Training 

• 47:29 – Cold Therapy Fails 

• 49:42 – Science of Crying 

• 54:51 – Reflections on Legacy 

• 59:37 – Balancing Stress and Ease 

• 01:10:30 – Nature and Spirituality 

• 01:22:52 – Facing Death with Grace 

• 01:32:53 – Closing Thoughts 

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