74 episodes

SKRAPS is your podcast where we, on your behalf explore the stories of sparks of scientific brilliance in science and innovation. SKRAPS is the word sparks spelt backwards and also a play on the idea that ideas are written on back of a napkin or scraps of paper. We explore stories of people in science, while elaborating on the scientific details so that experts and non-experts can relate to science better in today's whimsical world that acts to spread mis-information.

SKRAPS of Science & Innovation SKRAPS Studio

    • Science
    • 5.0 • 2 Ratings

SKRAPS is your podcast where we, on your behalf explore the stories of sparks of scientific brilliance in science and innovation. SKRAPS is the word sparks spelt backwards and also a play on the idea that ideas are written on back of a napkin or scraps of paper. We explore stories of people in science, while elaborating on the scientific details so that experts and non-experts can relate to science better in today's whimsical world that acts to spread mis-information.

    S4 E7: Investing (exclusively!!) in Bioelectronic Medicines

    S4 E7: Investing (exclusively!!) in Bioelectronic Medicines

    We are joined by https://www.linkedin.com/in/imraneba/ (Imran Eba) of GlaxoSmithKline's Bioelectronic Medicine fund - https://www.actionpotentialvc.com/ (Action Potential Venture Capital )to talk about investing in Bioelectronic Medicines. APV is the only fund that invests exclusively in bioelectronic medicines - and they've been here since the beginning.

    This leads to the ongoing question: what is and what is not a bioelectronic medicine (hear all three answers.)
    After we get through the personal grooming habits of the hosts and our guest as well as the obligatory cricket references (it's hard to put JoJo on her heels in professional sports parlance - but Arun and Imran manage to keep her quiet for a record time) we launch into a casual conversation about what's happening in neurotech investing.
    We talk about the trials and tribulations of how the world perceives Bioelectronic Medicines, what it should be, and what the reality is. Generously, Imran also shares with us some insights that every investigator, inventor, and investor should consider when preparing to raise funds in the field of neurotechnology, wait, no - BCIs, no -neuromodulation, gah - I mean... bioelectronic medicine.
    And if you are looking for the framework for Bioelectronic Medicine that we discuss, you can get it https://skrapspodcast.com/podcasts/bioelectronic-medicines-whats-in-a-name/ (here. )


    Special thanks to our sound engineer, Mr. Swaminathan ThiruGnanaSambandam for his artsy work on audio mixing/mastering and sound design for this episode.


    Special thanks to our sponsors, https://www.cortec-neuro.com/ (CorTec Neuro) and https://www.cirtecmed.com/ (Cirtec Medical).


    Podchaser: 6xQc3dDQaIFab7JcLAab

    • 1 hr 18 min
    S4 E6: Research Pioneers ft. Ian Burkhart & Benjamin Stecher

    S4 E6: Research Pioneers ft. Ian Burkhart & Benjamin Stecher

    Most of us can pretty certainly say that we are alone within our heads. We may joke about inner voices, but what really happens when there genuinely is an external influence deep within a brain? The answer?
    In the case of two research pioneers, https://www.linkedin.com/in/ianburkhart/ (Ian Burkhart) and https://www.linkedin.com/in/benjamin-stecher-86706420/ (Benjamin Stecher), the answer is nothing short of a miracle. These two souls both underwent life altering surgeries - not just in terms of literally allowing a device to tap into their brains, but surgeries that would do for them what no pill, no prayer, and no person could do for them.
    Ian Burkhart was paralysed after a spinal cord injury endured while on holiday. What should have been a celebratory day at the beach, enjoyed, recorded, and then stored in his memory bank for future reflection ended in severe physical disability. Ian now serves as a Vice President of the North American Spinal Cord Consortium and is an advocate, speaker, and research pioneer.
    Benjamin Stecher was handed a diagnosis of Parkinson’s Disease at the impossibly early age of 29. He should have been enjoying what many of us believe are the prime years of adulthood when, instead, he was trying desperately to hold on to a “normal” life. He scoured manuscripts, spoke to experts, tested pharmaceutical cocktails to curtail the progression of his disease. Benjamin is an author, advocate, and chair of the Rune Labs Patient Advisory Board.
    Both of these lionhearted men decided to do what few have done - they have invited a device to take up residence in their respective brains. Listen in to hear the first hand accounts of the what, why, and how they have gone to such lengths. We’ll share with you their stories and their triumphs, and certainly their challenges along the way. At the end of this tale, you will know that both are superhuman, but not for the reasons you may think. You’ll hear about their journeys that have turned them into authors and advocates, and above all, men of science.
    Learn more about Ian Burkhart through the https://www.ianburkhartfoundation.org/ (Ian Burkhart Foundation) and read Benjamin’s book, “https://www.amazon.co.uk/Brain-Fables-Neurodegenerative-Diseases-Blueprint-ebook/dp/B088T85GMF (Brain Fables)”.
    Special thanks to our sponsors, https://www.cortec-neuro.com (CorTec Neuro) and https://www.cirtecmed.com (Cirtec Medical).


    Research and Interviews: JoJo Platt
    Script: Arun Sridhar
    Editing: Arun Sridhar
    Sound design: Arun Sridhar and Swaminathan ThiruGnanaSambandam
    Audio engineering/mastering: Swaminathan ThiruGnanaSambandam

    • 1 hr
    S4 E5: The Killing

    S4 E5: The Killing

    PUT YOUR HEADPHONES ON!
    What does a 4 cm long and 25g in weight crustacean have to teach us about Bioelectronic Medicine and human health? And what does its feeding habits have to tell us about how we deal with tumours?
    Well, there is more than what meets the eye! If we reveal more than this, we are breaking the plot to you and making your life easy.


    So, it is time to do the hard yards and go on this underwater exploration first, before we figure out a new frontier for Ultrasound modulation of nerve tumours (in this case - glioblastoma). We cover https://www.linkedin.com/in/vijay-agarwal-a33595227/ (Dr. Vijay Agarwal )and his company - https://www.alpheusmedical.com/ (Alpheus Medical) for what they are dreaming of, having been inspired by this seemingly innocuous crustacean that has links to World War II, submarines, symbiotic relationships and sonodynamic therapy?


    Can Alpheus Medical help treat cancer? There is only way to find out. But first, listen to this journey!


    Our deepest thanks to https://www.cortec-neuro.com/ (CorTec Neuro) and http://cirtecmed.com/ (CirTec Medical) for their kind help in bringing these episodes to you.




    Useful links:


    Our website: https://www.skrapspodcast.com/ (www.skrapspodcast.com)
    Donation Page: https://www.skrapspodcast.com/donate (www.skrapspodcast.com/donate)
    Our https://www.linkedin.com/company/skrapspodcast/ (LinkedIn)
    Our https://mobile.twitter.com/podcastskraps (Twitter)

    • 58 min
    S4 E4: The Ultrasounds of Silence

    S4 E4: The Ultrasounds of Silence

    The saying, as grotesque as it might be, goes "there's more than one way to skin a cat." In our case, there's more than one way to stimulate a nerve and we've gathered some experts leading the charge (pun very much intended.) Gather around the fire, bring some marshmallows and listen in as we chat with https://soniclab.umn.edu/ (Hubert Lim) of the University of Minnesota, https://www.ge.com/research/people/chris-puleo (Christopher Puleo) of GE Research, and https://shapirolab.caltech.edu/ (Mikhail Shapiro )of CalTech about the power and the fury of ultrasound.
    There are two things that are guaranteed with this group - you will laugh and you will learn something. So, please forgive our indulgences as we dig into the when, the why, and the how this unlikely team came to be and all that they've accomplished so far.
    To kick off the laugh track, https://www.youtube.com/watch?v=sVPCe8Y5EnM (Hubert) and https://www.youtube.com/watch?v=UZ_AU1wpGxA (Mikhail) were kind enough to share some wicked awesome dance moves from each of their respective labs. The Solid Gold Dancers have been put on notice.


    Our deepest thanks to https://www.cortec-neuro.com/ (CorTec Neuro) and http://cirtecmed.com/ (CirTec Medical) for their kind help in bringing these episodes to you.




    Useful links:


    Our website: https://www.skrapspodcast.com (www.skrapspodcast.com)
    Donation Page: https://www.skrapspodcast.com/donate (www.skrapspodcast.com/donate)
    Our https://www.linkedin.com/company/skrapspodcast/ (LinkedIn)
    Our https://mobile.twitter.com/podcastskraps (Twitter)

    • 1 hr 13 min
    S4 E3: Basic Bench - Bedside Considerations For Bioelectronic Medicines

    S4 E3: Basic Bench - Bedside Considerations For Bioelectronic Medicines

    Have you ever wondered what decisions go behind deciding if a pharmaceutical is to be administered either orally or intravenously or via inhalation. Who decides that? Well, the short answer is that it is decided based on a tested pharmaceutical developmental framework that has stood the test of time. First, it is determined by a clinical need, then by what the drug does to the body (pharmacodynamics) and what the body does to the drug (pharmacokinetics) married with other commercial question.
    Now, if we flip it to Bioelectronic Medicines, we have realized that the field does not have an established framework that is available for everyone to discuss. So we sought to establish that via this episode.


    We are joined by https://www.linkedin.com/in/pikov (Dr. Victor Pikov), who unpicks these crucial questions, as it pertains to Bioelectronic Medicines. We discuss all the crucial questions that needs to be discussed and considered.


    Special thanks to https://www.linkedin.com/in/lauraneuro (Laura Szklarski) for providing us with a great testimonial and some key actions for you to consider.


    Our deepest thanks to https://www.cortec-neuro.com/ (CorTec Neuro) and http://cirtecmed.com/ (CirTec Medical) for their kind help in bringing these episodes to you.


    SKRAPS will always remain free, but production of SKRAPS is not. We appreciate kind, recurring donations to help produce such content. You can find more information https://skrapspodcast.com/donate/ (HERE).

    • 56 min
    S4 E2 Depression Rx: The Tale of SAINT Magnus

    S4 E2 Depression Rx: The Tale of SAINT Magnus

    Join Arun and JoJo as they go behind the wall of the science that underpins new treatments for Major Depressive Disorder (MDD).
    While MDD is the leading cause of both personal and societal disability, there are still inadequate treatment options. But the advent of two very areas are bringing hope! The first area is psychedelic assisted psychotherapy that we covered in our psychedelic series - Episode 7 and Episode 8. And second, more exciting and frankly a profound option is the use of the language that the brain uses to communicate and turn that into a treatment.
    In this episode, we are joined by two wonderful individuals - https://profiles.stanford.edu/nolan-williams;jsessionid=3F5339774B4725517E0E3FFE69B16F43.cap-su-capappprd99 (Dr. Nolan Williams), Asst Professor at Stanford University and https://www.linkedin.com/in/wingeier (Dr. Brett Wingeier).


    Nolan is both a psychiatrist and a neurologist and with an impressive training. He takes and compresses (quite literally) all the learnings from https://pubmed.ncbi.nlm.nih.gov/15748841/ (deep brain stimulation) and Transcranial Magnetic stimulation into developing a bespoke theta burst stimulation, and identifying it for a distinct patient population for its first adaptation - in hospital, psychiatric emergency.


    Brett Wingeier, the CEO of https://www.magnusmed.com/about/ (Magnus Medical) is spearheading the development and commercialisation of the https://pubmed.ncbi.nlm.nih.gov/32252538/ (SAINT (Stanford Accelerated Intelligent Neuromodulation Trial) )technology via his company, Magnus Medical. In fact, based on the results of their https://pubmed.ncbi.nlm.nih.gov/34711062/ (most recent trial), Magnus Medical was offered a breakthrough device designation by FDA.


    Join us as we uncover the science of this wonderful field and how Bioelectronic medicine is moving from movement disorders like Parkinson’s disease to positively impacting mental health.


    This is something that you will hopefully not get anywhere else in one piece.

    • 1 hr 3 min

Customer Reviews

5.0 out of 5
2 Ratings

2 Ratings

Sandhyanag ,

One of the best narrative podcasts ever made

Amazing manner in which the PsychedeRx series is narrated. Cool sound design and spectacular audio quality. The hosts do a great job!

Top Podcasts In Science

Sam Harris
BBC Radio 4
Stak
BBC Radio 4
Jordan Harbinger
Hidden Brain

You Might Also Like