SKRAPS Studio

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Channel • 2 Shows

Documentary

Documentary

Updated 21/12/2021
Life Sciences

Life Sciences

Updated 12/03/2025

19/10/2021

Episode 5: Basic Pharmacology of Serotonin & Psychedelics

We’ve spent some time already on the definition of psychedelic - and we’ll spend more time before this series is over. But, Skraps is a podcast whose roots are run deep in the sciences, we couldn’t ignore the topic of the basic pharmacology of psychedelics. This episode is a primer for citizen scientists and holds some intriguing information for the bonafide scientists among us. As always, we don’t just deliver science, we are going to start with core science and intertwine the stories of the people who made the discoveries - ultimately ending with an understanding of how psychedelics work. We’ll feature the work of Dr. Joanna Neill, a pharmacologist and Chair of the Psychedelics Working Group for Drug Science UK. Dr. Bryan Roth also joins us; Bryan is a professor of pharmacology at the University of North Carolina studying psychedelics with a pretty serious DARPA grant. For a special treat, you’ll get to hear JoJo absolutely butcher some basic biology and pharmacology terms. Please DM Arun and let him know that you’d like to get the bonus out-takes of PsychedeRx. This podcast series is made possible by kind donations. If you wish to donate to our cause of spreading factual stories of science, scientists and innovations, please click here: https://skrapspodcast.com/donate/ This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

19/10/2021

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1hr 31min
15/06/2021

#PsychedeRx Episode 5: Basic Pharmacology of Psychedelics

We’ve spent some time already on the definition of psychedelic - and we’ll spend more time before this series is over. But, Skraps is a podcast whose roots are run deep in the sciences, we couldn’t ignore the topic of the basic pharmacology of psychedelics. This episode is a primer for citizen scientists and holds some intriguing information for the bonafide scientists among us. As always, we don’t just deliver science, we are going to start with core science and intertwine the stories of the people who made the discoveries - ultimately ending with an understanding of how psychedelics work. We’ll feature the work of Dr. Joanna Neill, a pharmacologist and Chair of the Psychedelics Working Group for Drug Science UK. Dr. Bryan Roth also joins us; Bryan is a professor of pharmacology at the University of North Carolina studying psychedelics with a pretty serious DARPA grant. For a special treat, you’ll get to hear JoJo absolutely butcher some basic biology and pharmacology terms. Please DM Arun and let him know that you’d like to get the bonus out-takes of PsychedeRx.

15/06/2021

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1hr 29min
22/12/2020

E19: What if you were a Psychopath? - w/ Dr. James Fallon

Have you ever wondered or seen someone and thought they could be a psychopath or have psychopathic tendencies? What if you found out if you really had the all the attributes of being a psychopath? Does it make you question everything you have experienced and have been trhough wondering what if you had flipped and why you hadn't flipped yet? This is exactly what happened to our guest., Dr. James Fallon. His journey, chronicled in the book (Link Here) outlines and we had a fantastic conversation with him. Listen in and find out about this stellar scientist and a great story teller.

22/12/2020

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1hr 11min
16/07/2021

#PsychedeRx Episode 7: PTSD and Psychedelics: Making "Unconventional" Conventional!

A cast will help a broken bone to heal, a tourniquet will help to stop the bleeding in a limb, an aspirin will alleviate a headache, time (and ice cream) will help to heal a broken heart. But how do you heal a broken mind? Post Traumatic Stress Disorder (PTSD) is but one of the psychiatric indications with inadequate, frequently ineffective treatment protocols, that has been in the psychedelic spotlight. There’s no shortage of heartbreaking stories about men and women who have dedicated their lives to the service of their countries and endured unfathomable trauma. Add to this population the other sources of PTSD like car accidents, witnessing or experiencing violence - or even the threat of violence, sustained stress in traumatic situations (hello, COVID frontline workers - I’m looking at you), and you have an explosion in an untreated or treatment refractory population. Enter psychedelics. In this episode, we are privileged to hear from Jesse Gould, a former Army Ranger, and Keith Abraham, a former member of the UK’s Parachute Regiment. These gentlemen both served their countries in combat tours in the Middle East and have suffered the invisible injuries of war. Each found his way to ayahuasca as a means of resolving his PTSD when pharmacological, talk therapy, and wholistic approaches failed him. Ayahuasca healed them when nothing else could; now, through their connected organizations - Heroic Hearts Project and Heroic Hearts Project UK - they are helping other veterans gain access to this highly promising combination therapy of psychedelics and psychiatry in what is now known as psychedelic-assisted psychotherapy. In addition, we explore the story of how MDMA assisted psychotherapy, pioneered by MAPS' pivotal trials were done in an interview with Dr. Jennifer Mitchell This episode will take you into the personal stories, the science, the history, the future, and the promise of psychedelic-assisted psychotherapy for PTSD. Grab a tissue, you’re going to need it. (And then go donate to Heroic Hearts Project so that we can help more people heal.)

16/07/2021

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1hr 45min
21/12/2021 · Bonus

Bonus Episode No.3: What's a trip really like?

If you’ve listened to the PsychedRx series, or ever contemplated experiencing psychedelics, you’ve probably asked yourself what a trip is really like. Well, I’d very much like to tell you what it’s like, but it’s much like trying to describe an exact shade of purple velvet. It’s deep, rich, bright, dark, it changes as the light shifts. When you touch it, everything changes. It’s different in the morning than it is at night. It’s simultaneously warm and cool, comforting and challenging, but it’s something you can’t fully appreciate or describe without seeing it in person. For additional exploration and examination, we’ve engaged a first-rate scientist and psychonaut of sorts to help us understand, as best we can… With that, we’d like to thank Juan for sharing his experiences and perspectives with us. We’d also like to thank all of our participants for their time, dedication, talent, and insights. Finally, we’d like to thank each of you for taking this journey with us. Hazzah! This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

21/12/2021 · Bonus

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42 min
24/02/2025

Sudor Anglicus: The English Sweating Sickness

What connects Tudor England, Ann Boleyn, Henry the VIII, autonomic nervous system and a flash mob like wave of a deadly disease? There is only way to find out. Inspired by this paper and Dr. Ali Christy's X thread. SKRAPS is your podcast, where we on your behalf explores unsaid, underappreciated and sometimes, untold stories of sparks of brilliance in science, technology and innovation. Created & Produced by: Arun Sridhar You can help us fund the production costs by donating as a one time or a recurring payment HERE

24/02/2025

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23 min
29/09/2021

Episode 2: Mescaline: The OG of Psychedelics

Peyote crosses the border and causes a riot. Drug companies want their taste, and psychedelics reach the social elite. What could possibly go wrong? In episode two of PsychedeRx, Peyote comes north to the good old US of A. And it’s not just for religious ceremonies anymore, either. Spanish conquistadors and European explorers, seeking to dominate the indigenous tribes, used Peyote to show force by banning its use and denying the tribes their spiritual practices. And we all know what happens when prohibitions are imposed - the use doesn’t stop, it just gets moved underground. James Mooney, an ethnographer dispatched by the Smithsonian Institute, is one of our best resources for this era. He committed to his diary first-hand accounts of the use of and backlash against peyote in tribal rituals. As Peyote moved north, albeit underground, it became the catalyst for a series of events that were bloodier than an episode of Dexter. Wovoka and the Ghost Dance were the turning point. The execution of Sitting Bull led to the massacre at Wounded Knee - and it was all over peyote and freedom of religion - ain’t that an ironic twist? Episode two also sheds light on the earliest interventions of the drug companies like Merck and Parke-Davis and their part in our little psychedelic drama. Arthur Heffter separates the resins from the alkaloids and isolates the first real information on dosing. We get a close-up look at how the psychiatrists and psychologists got involved - where they got it right, and where they got it all wrong. Psychedelics also make their way into the world of the social elites through folks like Aldous Huxley and Ken Kesey. We’ll close out this week with our first peek at LSD. So remember to “Turn on, tune in, and drop out.” This documentary series is made possible by our kind donors. Kindly help us by donating to our cause of disseminating factual stories of science, scientists and innovations at https://skrapspodcast.com/donate/ This podcast uses the following third-party services for analysis: Podcorn - https://podcorn.com/privacy

29/09/2021

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1hr 1min
18/03/2022

S4 E5: The Killing

PUT YOUR HEADPHONES ON! What does a 4 cm long and 25g in weight crustacean have to teach us about Bioelectronic Medicine and human health? And what does its feeding habits have to tell us about how we deal with tumours? Well, there is more than what meets the eye! If we reveal more than this, we are breaking the plot to you and making your life easy. So, it is time to do the hard yards and go on this underwater exploration first, before we figure out a new frontier for Ultrasound modulation of nerve tumours (in this case - glioblastoma). We cover Dr. Vijay Agarwal and his company - Alpheus Medical for what they are dreaming of, having been inspired by this seemingly innocuous crustacean that has links to World War II, submarines, symbiotic relationships and sonodynamic therapy? Can Alpheus Medical help treat cancer? There is only way to find out. But first, listen to this journey! Our deepest thanks to CorTec Neuro and CirTec Medical for their kind help in bringing these episodes to you. Useful links: Our website: www.skrapspodcast.comDonation Page: www.skrapspodcast.com/donateOur LinkedIn Our Twitter

18/03/2022

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59 min
11/05/2021

#PsychedeRx Episode 1 - Psychedelics: The Fun, The Fantastical & the Facts!

Where were you on June 18, 1971? Did you know that was when Richard Nixon, the United Nations, and other world leaders changed the course of popular culture, scientific experimentation, and mind exploration for the next five decades? Did you know that substances that have the potential to change the way we treat myriad diseases and conditions - ones that have little or no reliable treatments today - were fated on that day to be imprisoned like Hannibal Lecter? Join us for the first of a series of Skraps Original episodes as we explore the use, misuse, and history of psychedelics. In this episode, we will cover the most important question of what these substances are, and begin to question why they were lumped in with other addictive substances by exploring the history of how curiosity-induced exploration on one side clashed with religious single-mindedness. This manifested itself in how these plant-based substances were viewed then and for centuries later, in the eyes of the western world. PsychedeRx will cover the ancient history of plant-based psychedelics including their religious, ceremonial, tribal uses and the dangers imposed by the European views of those uses. We’ll experience murder, mayhem, executions, displacement, and more. We’ll talk to psychedelic historian Mike Jay to get the full story of the full journey - one that started long before Nixon and other world powers set their limited, short-sighted fear loose upon the world. Subscribe to SKRAPS on your favorite podcast platform to make sure you don’t miss a minute of this riveting journey.

11/05/2021

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1hr 16min
25/05/2021

#PsychedeRx Episode 3: The Doors Are Blown Open

Drug discovery doesn’t happen in a vacuum. So much of the world’s geopolitical activities affect what happens both inside and outside of the lab. Lysergic Acid Diethylamide was such a curious drug that there were seemingly no limits to how and when it would be tested. Episode three of PsychedeRx kicks off with an LSD-laden military training exercise. Don’t laugh. It really did happen and we have the tapes to prove it. All in the name of science, right? We bring back Mike Jay from Episode Two to bring some of the highlights from the lab of Albert Hoffman and how his cult-favorite bicycle “trip.” A day now celebrated around the world. We’ll see how Sandoz, the Swiss pharmaceutical company, passed out LSD to psychiatrists around the world in an attempt to find out just what the heck this chemical could really be used for - including as a possible cure for alcoholism. As always, we want you to listen in and ask the hard questions. Were these incidents that shaped the reputation and the future of these substances use or misuse? Were they inherently bad, or was it their handling that earned the demonized notoriety? Hoffman's Potion Documentary Link: CLICK HERE

25/05/2021

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55 min

SKRAPS Studio explores the stories sparks of scientific brilliance in science and innovation through its interview based podcast (SKRAPS Podcast) and its scripted narrative audio documentary series.

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SKRAPS Studio

Top Shows

Episode 5: Basic Pharmacology of Serotonin & Psychedelics

#PsychedeRx Episode 5: Basic Pharmacology of Psychedelics

E19: What if you were a Psychopath? - w/ Dr. James Fallon

#PsychedeRx Episode 7: PTSD and Psychedelics: Making "Unconventional" Conventional!

Bonus Episode No.3: What's a trip really like?

Sudor Anglicus: The English Sweating Sickness

Episode 2: Mescaline: The OG of Psychedelics

S4 E5: The Killing

#PsychedeRx Episode 1 - Psychedelics: The Fun, The Fantastical & the Facts!

#PsychedeRx Episode 3: The Doors Are Blown Open

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