30 episodes

If you like what you hear and would like to show us your support, please hit the Bell to follow this podcast for more life-changing microbiome insights! Thank you!

Join us on a journey to discover the wonders of microbiome research in the Microbiome Mavericks Podcast. Learn about dysbiosis and its link to inflammatory diseases caused by antibiotics, diet, and lifestyle. Gain insight from prominent researchers on protecting and improving our microbiomes. Discover the newest technologies used to mine our gut microbiomes and explore far-reaching places like space and the ocean depths.

The Microbiome Mavericks Dr. Amine Zorgani

    • Science

If you like what you hear and would like to show us your support, please hit the Bell to follow this podcast for more life-changing microbiome insights! Thank you!

Join us on a journey to discover the wonders of microbiome research in the Microbiome Mavericks Podcast. Learn about dysbiosis and its link to inflammatory diseases caused by antibiotics, diet, and lifestyle. Gain insight from prominent researchers on protecting and improving our microbiomes. Discover the newest technologies used to mine our gut microbiomes and explore far-reaching places like space and the ocean depths.

    From Microgravity to Microbiomes: The Interstellar Journey With The Scientist Fathi Karouia

    From Microgravity to Microbiomes: The Interstellar Journey With The Scientist Fathi Karouia

    Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    In this episode, we have the pleasure of speaking with Fathi Karouia, Senior Research Scientist @NASA | Space Life Science Subject Matter Expert | Consultant | Entrepreneur and a Speaker whose work combines two of the most intriguing subjects on our planet: space and microbiomes.

    Fathi shares his insights into the complex interactions between microbes and the harsh environment of space, and how this research not only contributes to our understanding of space exploration but also has practical applications here on Earth.

    Fathi's team discovered that bacteria grow faster, are more resistant to stress and antibiotics, and tend to form biofilms in microgravity conditions. Remarkably, a strain of Bacillus pumilus was found to be 1000 times more resistant to UV radiation than other strains, even surviving exposure outside the International Space Station for 18 months. Wow! Just that!

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about Fathi Karouia here: https://www.linkedin.com/in/fathikarouia/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠




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    • 57 min
    The Regulators' Lens on Microbiome Product Development With Clara Desvignes

    The Regulators' Lens on Microbiome Product Development With Clara Desvignes

    Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    This podcast episode will cover regulatory affairs for microbiome products like probiotics, live biotherapeutics, and fecal microbiota transplants with My guest, Clara Desvignes from Voisin Consulting.

    Clara discusses the lack of a clear regulatory framework specifically for microbiome products currently, which poses challenges but also opportunities to help shape the emerging guidelines and pathways.

    The discussion reminds us that robust science, thorough documentation, and open dialogues with authorities are vital for translating promising microbiome innovations into approved therapies that improve patient outcomes. Consulting firms with regulatory expertise can help companies navigate this complex landscape effectively.

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about Clara Desvignes here: https://www.linkedin.com/in/clara-desvignes/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠


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    • 35 min
    From Diabetes to Dementia: A Gut Microbiome Exploration With Dr Hariom Yadav

    From Diabetes to Dementia: A Gut Microbiome Exploration With Dr Hariom Yadav

    Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    In this new episode, I have the pleasure of speaking to Dr. Hariom Yadav, Director of University of south Florida center of Microbiome Research. Dr. Hariom is a leading expert in the field of gut microbiome research, with a particular focus on its role in diabetes, aging, and cognitive function. His work has led to significant discoveries in understanding the intricate relationship between diet, gut health, and chronic diseases.

    Dr. Hariom's research has revealed that the gut microbiome plays a crucial role in regulating gut permeability, also known as "leaky gut." His study demonstrated that transferring the microbiome from obese mice to lean mice induced leaky gut and inflammation, leading to insulin resistance and increased risk of type 2 diabetes. This finding underscores the importance of maintaining a healthy gut microbiome through proper diet and lifestyle choices.

    Furthermore, Dr. Hariom's work explores the gut-brain axis. He emphasizes that the gut harbors as many neurons as the brain, and imbalances in the gut microbiome can contribute to cognitive decline and neurodegenerative disorders. His research aims to develop microbiome-based biomarkers to predict the risk of dementia and Alzheimer's disease, potentially leading to early intervention strategies.

    As an entrepreneur, Dr. Hariom has co-founded a company called PostBiotics Inc., which focuses on developing postbiotic-based solutions for reducing leaky gut and inflammation. His innovative approach targets the cellular components of beneficial bacteria, rather than relying solely on live probiotics. This technology has shown promising results in animal studies, demonstrating its potential to improve muscle health, metabolic function, and overall longevity.

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about Dr Hariom Yadav here: https://www.linkedin.com/in/yadavhariom/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠




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    • 58 min
    Why Prebiotic Whole Foods May Be the Missing Health Link – David Istier @Gutzy

    Why Prebiotic Whole Foods May Be the Missing Health Link – David Istier @Gutzy

    Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    Today, I have the pleasure of speaking to David Istier, founder of Gutsy, about the important role of prebiotics for gut and overall health. My first key takeaway is that prebiotics offer an accessible way to improve health. While found naturally in fruits, veggies, and other plant foods, most Americans fall short of getting enough. David started Gutsy to provide an easy prebiotic snack to help bridge nutritional gaps.

    Additionally, not all prebiotics are the same. Gutsy focuses on organic acacia fiber which research shows selectively feeds good bacteria. Acacia also supports digestive health, immunity, energy levels, and more. It's a simple change that can yield real benefits.

    Finally, good gut health starts early. Establishing a fiber-rich diet in childhood supports microbiome diversity and lifelong wellbeing. Gutsy caters to adults and kids alike. As David shared, "Eating for good health is eating for the pleasure towards the vitality and energy to live our best life."

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about Gutzy here: https://gutzyorganic.com/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠




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    Send in a voice message: https://podcasters.spotify.com/pod/show/amine-zorgani/message

    • 46 min
    What Is Microbiome Friendliness With Leo Salvi From Kind To Biome

    What Is Microbiome Friendliness With Leo Salvi From Kind To Biome

    Hello and welcome to the Microbiome Mavericks Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    Today, I have the pleasure of speaking to Leo Salvi, Head of Science at Kind to Biome. Leo joins me today to discuss the important role our skin microbiome plays in maintaining skin health. He sheds light on how the cosmetics industry is responding to the emerging science showing links between skin conditions like acne and disruption to the skin’s delicate microbial balance. We’ll be unpacking what it really means when brands make “microbiome-friendly” claims about their skincare products. How do we know if a product supports versus disturbs the trillions of microbes on our skin? And how is this different from the “clean beauty” movement?

    Over the course of our conversation, Leo shares critical insights for both consumers and brands interested in tapping into microbiome science to enhance skincare routines and products.

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about Kind To Biome here:
    https://www.kindtobiome.com/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠




    ---

    Send in a voice message: https://podcasters.spotify.com/pod/show/amine-zorgani/message

    • 33 min
    The Untold Story of Probiotics With Gianfranco Grompone @BioGaia AB

    The Untold Story of Probiotics With Gianfranco Grompone @BioGaia AB

    Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

    I recently had the pleasure of interviewing Gianfranco, Chief Scientific Officer at BioGaia, for my podcast "The Microbiome Mavericks." He shared great insights that can help us better understand probiotics.

    Gianfranco explained how he became fascinated with gut microbiome interactions with human health, which led him into the probiotics industry in 2005. His goal is to study how certain bacteria can positively influence health.

    A probiotic must be a specifically identified strain, clinically proven to provide a health benefit to the host. For example, L. reuteri DSM 17938 has significant clinical evidence supporting its ability to reduce colic in infants. Probiotics "speak different languages" with our immune systems, so strain specificity really matters.

    You will also learn that the most important factor in a probiotic form (capsule, tablet, drops) is maintaining the clinically proven effective concentration. The delivery matrix depends on what's convenient for the age and needs of the consumer.

    The research Gianfranco shared on next-generation probiotic F. prausnitzii was fascinating. This strain is missing in certain diseases but helps produce beneficial metabolites. His team found a way to train it to resist oxygen, allowing it to be delivered in supplement form to people missing these microbes. Exciting stuff!

    Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

    You can find more about BioGaia AB here: https://www.biogaia.com/

    You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

    If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠dr.amine@microbiomemavericks.com⁠⁠




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    Send in a voice message: https://podcasters.spotify.com/pod/show/amine-zorgani/message

    • 46 min

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