IMNano IMNano

Super amazing chemistry



References:

Ruizhe Chen et al.,Alcohol-alcohol cross-coupling enabled by SH2 radical sorting.Science383,1350-1357(2024).DOI:10.1126/science.adl5890

https://chemistry.princeton.edu/news/macmillan-lab-scores-alcohol-alcohol-cross-coupling-method-after-long-effort/#:~:text=The%20method%3A%20achieving%20alcohol%2Dalcohol,by%20powerful%20SH2%20radical%20sorting.&text=The%20alcohol%2Dalcohol%20paper%E2%80%94the,salt%20to%20form%20activated%20adducts.

The Nobel Prize winning scientists, Frances Arnold, has done it again! Her team have use directed evolution to engineer enzymes that can break down the strong carbon-silicon bonds found in many products we use everyday!



Reference:
Nicholas S. Sarai et al. ,Directed evolution of enzymatic silicon-carbon bond cleavage in siloxanes.Science383,438-443(2024). DOI:10.1126/science.adi5554



Intro/Outro music:

Music by ⁠minwbu⁠ from ⁠Pixabay

Time for a nanolife interview with the one and only Dr Thomas Mortelmans who delves deep into his medical biosensor and how he came out his various inventions!

Check out his main biosensor work that we talk about here:


ACS Appl. Nano Mater. 2022, 5, 1, 517–526

doi.org/10.1021/acsanm.1c03309

And you can follow and connect with Tom here:

https://www.linkedin.com/in/thomas-mortelmans-ph-d-066a9a83/

https://orcid.org/0000-0002-0677-5857


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In this lit update we talk about a carbon nanotube sensor discovery that shows the current in a carbon nanotube device can pass parallel or perpendicular to the tubes and the results will be different!

Reference:

https://pubs.acs.org/doi/10.1021/acs.nanolett.3c02555  Nano Lett. 2023, 23, 21, 9817–9824

Let's review what we have accomplished, some of the missed research we didn't get to cover, and our favorite research in 2023!


Intro/Outro music:

Music by ⁠⁠⁠minwbu⁠⁠⁠ from ⁠⁠⁠Pixabay

Lit-Update Meet the Expert! where we get to dig deep into papers with the scientist themselves!


Have you ever wondered how changes to your normal schedule affects your health? Tune in to learn more about circadian disruption and health from Stéphanie Abo based on her paper "Can the Clocks Tick Together Despite the Noise? Stochastic Simulations and Analysis" published in SIAM Journal on Applied Dynamical Systems.



Stéphanie is a PhD Candidate in mathematical and computational biology at the University of Waterloo. Her academic research primarily explores the interaction between the circadian clock and metabolism in healthy and disease states (e.g., diabetes, bacterial infections). I use both data-driven and mechanistic modelling technique (PDEs, ODEs, stochastic DEs, kinetic theory and mean-field limits, agent-based modelling, and statistical methods).



References:
Abo, S. M. C.; Carrillo, J. A.; Layton, A. T. Can the Clocks Tick Together Despite the Noise? Stochastic Simulations and Analysis. SIAM J. Appl. Dyn. Syst. 2023, 22, 850-877 DOI:10.1137/22M147788X.




Intro/Outro music:

Music by ⁠⁠minwbu⁠⁠ from ⁠⁠Pixabay